4595
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25307
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Biologie synthétique
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Publications
4595 publication(s) trouvée(s)
Article scientifique
Metabolome response to temperature-induced virulence gene expression in two genotypes of pathogenic Vibrio parahaemolyticus
BACKGROUND: Vibrio parahaemolyticus is a main causative agent of serious human seafood-borne gastroenteritis disease. Many researchers have investigated its pathogenesis …
Article scientifique
Clinical and pathological features of BRCA1/2 tumors in a sample of high-risk Moroccan breast cancer patients
BACKGROUND: BRCA1 and BRCA2 genes explain a large part of hereditary breast cancer. Several studies have shown that BRCA1 and …
Article scientifique
Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets
Research focusing on type 1 diabetes (T1D) autoantigens aims to explore our understanding of these beta cell proteins in order …
Article scientifique
An exploratory study of volumetric analysis for assessing tumor response with 18F-FAZA PET/CT in patients with advanced non-small-cell lung cancer (NSCLC)
BACKGROUND: Hypoxia is associated with resistance to chemotherapy and radiotherapy and is randomly distributed within malignancies. Characterization of changes in …
Article scientifique
Evaluation of the OvineSNP50 chip for use in four South African sheep breeds
Relatively rapid and cost-effective genotyping using the OvineSNP50 chip holds great promise for the South African sheep industry and research …
Article scientifique
Aspergillus Oryzae S2 α-Amylase Domain C Involvement in Activity and Specificity: In Vivo Proteolysis, Molecular and Docking Studies
We previously reported that Aspergillus oryzae strain S2 had produced two α-amylase isoforms named AmyA and AmyB. The apparent molecular …
Article scientifique
Determination of Phytochemical Compounds, and Tyrosinase Inhibitory and Antimicrobial Activities of Bioactive Compounds from Streblus ilicifolius (S Vidal) Corner
Purpose: To determine the phytochemical content, and tyrosinase inhibitory and antimicrobial activities of the wood from Streblus ilicifolius (S. Vidal) …
Article scientifique
Design, synthesis and anticancer activity of some novel thioureido-benzenesulfonamides incorporated biologically active moieties
BACKGROUND: Many thiourea derivatives have exhibited biological activities including anticancer activity through several mechanisms. On the other hand, benzenesulfonamide derivatives …
Article scientifique
Proteogenomic Analysis of Mycobacterium smegmatis Using High Resolution Mass Spectrometry
Biochemical evidence is vital for accurate genome annotation. The integration of experimental data collected at the proteome level using high …
Article scientifique
Polymorphisms of Estrogen Metabolism-Related Genes and Prostate Cancer Risk in Two Populations of African Ancestry
BACKGROUND: Estrogens are thought to play a critical role in prostate carcinogenesis. It has been suggested that polymorphisms of genes …
Article scientifique
The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined
Over the past two decades, huge amounts of research were launched to understand the functions of sphingosine. Many pathways were …
Article scientifique
Small Non-coding RNAs Associated with Viral Infectious Diseases of Veterinary Importance: Potential Clinical Applications
MicroRNAs (miRNAs) represent a class of small non-coding RNA (sncRNA) molecules that can regulate mRNAs by inducing their degradation or …
Article scientifique
Structured feature selection using coordinate descent optimization
BACKGROUND: Existing feature selection methods typically do not consider prior knowledge in the form of structural relationships among features. In …
Article scientifique
Association of MicroRNA-196a2 Variant with Response to Short-Acting β2-Agonist in COPD: An Egyptian Pilot Study
Chronic obstructive pulmonary disease (COPD) is a multifactorial chronic respiratory disease, characterized by an obstructive pattern. Understanding the genetic predisposition …
Article scientifique
Overconfidence, Incentives and Digit Ratio
This paper contributes to a better understanding of the biological underpinnings of overconfidence by analyzing performance predictions in the Cognitive …
Article scientifique
Antimalarial properties of crude extracts of seeds of Brucea antidysenterica and leaves of Ocimum lamiifolium
BACKGROUND: The search for new antimalarial drugs has become increasingly urgent due to plasmodial resistance to existing drugs. As part …
Article scientifique
Fluoroquinolone-Resistant Enteric Bacteria in Sub-Saharan Africa: Clones, Implications and Research Needs
Fluoroquinolones came into widespread use in African countries in the early 2000s, after patents for the first generation of these …
Article scientifique
Increased Free Circulating DNA Integrity Index as a Serum Biomarker in Patients with Colorectal Carcinoma
BACKGROUND: Cell-free DNA circulating in blood is a candidate biomarker for malignant tumors. Unlike uniformly truncated DNA released from apoptotic …
Article scientifique
Infections caused by extended-spectrum beta-lactamases producing Enterobacteriaceae: clinical and economic impact in patients hospitalized in 2 teaching hospitals in Dakar, Senegal
BACKGROUND: Infections caused by extended-spectrum beta-lactamases producing Enterobacteriaceae (ESBL-E) are of major concern in clinical practice because of limited therapeutic …
Article scientifique
Dynamics of the Developing Chick Chorioallantoic Membrane Assessed by Stereology, Allometry, Immunohistochemistry and Molecular Analysis
The chick chorioallantoic membrane (CAM) is a widely used model for the study of angiogenesis, tumour growth, as well as …