4595
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Biologie synthétique
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Publications
4595 publication(s) trouvée(s)
Article scientifique
Fungal Genomics Challenges the Dogma of Name-Based Biosecurity
Microorganisms have inadvertently been spread via the global movement and trade of their substrates, such as animals, plants, and soil.This …
Article scientifique
Genetic characterization of TEM-type ESBL-associated antibacterial resistance in Enterobacteriaceae in a tertiary hospital in Ghana
BACKGROUND: Antibiotic resistance due to the presence of extended-spectrum beta-lactamases (ESBLs) among Enterobacteriaceae is a worldwide problem. Data from Ghana …
Article scientifique
Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model
BACKGROUND: Gene-based virotherapy mediated by oncolytic viruses is currently experiencing a renaissance in cancer therapy. However, relatively little attention has …
Article scientifique
The Novel Gene VpPR4-1 from Vitis pseudoreticulata Increases Powdery Mildew Resistance in Transgenic Vitis vinifera L.
Pathogenesis-related proteins (PRs) can lead to increased resistance of the whole plant to pathogen attack. Here, we isolate and characterize …
Article scientifique
Glycosyltransferase Gene Expression Profiles Classify Cancer Types and Propose Prognostic Subtypes
Aberrant glycosylation in tumours stem from altered glycosyltransferase (GT) gene expression but can the expression profiles of these signature genes …
Article scientifique
A European Mitochondrial Haplotype Identified in Ancient Phoenician Remains from Carthage, North Africa
While Phoenician culture and trade networks had a significant impact on Western civilizations, we know little about the Phoenicians themselves. …
Article scientifique
Genetic Diversity and Population Structure in South African, French and Argentinian Angora Goats from Genome-Wide SNP Data
The Angora goat populations in Argentina (AR), France (FR) and South Africa (SA) have been kept geographically and genetically distinct. …
Article scientifique
Circulating Serum miRNAs as Diagnostic Markers for Colorectal Cancer
AIM: The study was designed to assess the possibility of using circulating miRNAs (serum miRNAs) as diagnostic biomarkers in colorectal …
Article scientifique
Quorum Sensing Inhibiting Activity of Streptomyces coelicoflavus Isolated from Soil
Quorum sensing (QS) systems communicate bacterial population and stimulate microbial pathogenesis through signaling molecules. Inhibition of QS signals potentially suppresses …
Article scientifique
Meta-analysis of proportion estimates of Extended-Spectrum-Beta-Lactamase-producing Enterobacteriaceae in East Africa hospitals
BACKGROUND: A high proportion of Extended-Spectrum-Beta-Lactamase (ESBL) producing Enterobacteriaceae is causing common infections in all regions of the world. The …
Article scientifique
microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection
Breast cancer (BC) is the most common cancer type and the second cause of cancer-related death among women. Therefore, better …
Article scientifique
ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan
Mutations in genes required for the glycosylation of α-dystroglycan lead to muscle and brain diseases known as dystroglycanopathies. However, the …
Article scientifique
Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database
With more than 30,000 species, ray-finned fish represent approximately half of vertebrates. The evolution of ray-finned fish was impacted by …
Article scientifique
Detection of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli in Market-Ready Chickens in Zambia
The frequent administering of antibiotics in the treatment of poultry diseases may contribute to emergence of antimicrobialresistant strains. The objective …
Article scientifique
Peer Review Report For: Transcription factor motif quality assessment requires systematic comparative analysis [version 2; peer review: 2 approved]
Transcription factor (TF) binding site prediction remains a challenge in gene regulatory research due to degeneracy and potential variability in …
Article scientifique
A game for crowdsourcing the segmentation of BigBrain data
The BigBrain, a high-resolution 3-D model of a human brain at nearly cellular resolution, is the best brain imaging data …
Article scientifique
Novel chloroquinoline derivatives incorporating biologically active benzenesulfonamide moiety: synthesis, cytotoxic activity and molecular docking
BACKGROUND: Quinoline derivatives have diverse biological activities including anticancer activity. On the other hand, many sulfonamide derivatives exhibited good cytotoxic …
Article scientifique
Evaluation of Anti-tumor and Chemoresistance-lowering Effects of Pectolinarigenin from Cirsium japonicum Fisch ex DC in Breast Cancer
Purpose: To investigate the antitumor and chemoresistance-lowering effects of pectolinarigenin on breast cancer cells.Methods: Pectolinarigenin was purified by a combination …
Article scientifique
Effect of Interaction of Methanol Leaf Extract of Spondias mombin (Linn) and Amoxicillin on Some Diarrheagenic Escherichia coli
Purpose: To study the effect of interaction between methanol leaf extract of Spondias mombin and amoxicillin on diarrheagenic Escherichia coli …
Article scientifique
Fluorescence imaging of in vivo miR-124a-induced neurogenesis of neuronal progenitor cells using neuron-specific reporters
BACKGROUND: Facilitation of the differentiation of the stem cells toward neuronal lineage is crucial for enhancing the differentiation efficacy of …