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Publications
4595 publication(s) trouvée(s)
Article scientifique
ERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy?
The MAP kinase signaling cascade Ras/Raf/MEK/ERK has been involved in a large variety of cellular and physiological processes that are …
Article scientifique
Evaluation of Immunomodulatory Effect of Immunace on Adjuvanticity of 1,2-Dioleoyl-3- trimethylammoniumpropane-based Liposomes
Purpose: To investigate the antibody effect of immunace on the adjuvanticity of 1,2-dioleoyl-3- trimethylammoniumpropane (DOTAP)- based liposomes.Method: The vesicles of …
Article scientifique
Effects of Triptergium Glycosides on Expressions of MCP- 1 and CTGF in Rats with Early Diabetic Nephropathy
Purpose: To investigate the effects of triptergium glycosides (TG) on expressions of monocyte chemoattractant protein-1 (MCP-1) and connective tissue growth …
Article scientifique
Ulmus davidiana var japonica Attenuates Neuroinflammatory Responses in Activated BV2 Murine Microglial Cells via Nuclear Factor-KappaB Signaling Pathway
Purpose: To investigate the antioxidant and anti-inflammatory effects of Ulmus davidiana extract (UDE) in lipopolysaccharide (LPS)-stimulated BV-2 cells.Methods: Antioxidant activity …
Article scientifique
The persistence and ecological impacts of a cyanobacterium genetically engineered to express mosquitocidal Bacillus thuringiensis toxins
BACKGROUND: The cyanobacterium Anabaena PCC 7120#11 has been genetically engineered to act as a delivery vehicle for Bacillus thuringiensis subspecies …
Article scientifique
Insulin-like growth factor type 1 deficiency in a Moroccan patient with de novo inverted duplication 9p24p12 and developmental delay: a case report
BACKGROUND: 9p duplication is a structural chromosome abnormality, described in more than 150 patients to date. In most cases the …
Article scientifique
Cytotoxic, anti-inflammatory and antioxidant activities of four different extracts of Galega officinalis L (Goat’s rue)
Purpose: To evaluate the cytotoxic, anti-inflammatory and antioxidant activities of four different solvent extracts obtained from the aerial parts of …
Article scientifique
Phylogenomic approaches to determine the zoonotic potential of Shiga toxin-producing Escherichia coli (STEC) isolated from Zambian dairy cattle
This study assessed the prevalence and zoonotic potential of Shiga toxin-producing Escherichia coli (STEC) sampled from 104 dairy units in …
Article scientifique
Investigations of immunogenic, allergenic and adjuvant properties of Cry1Ab protein after intragastric exposure in a food allergy model in mice
BACKGROUND: In genetically modified (GM) crops there is a risk that the inserted genes may introduce new allergens and/or adjuvants …
Article scientifique
A Designed Experiments Approach to Optimizing MALDI-TOF MS Spectrum Processing Parameters Enhances Detection of Antibiotic Resistance in Campylobacter jejuni
MALDI-TOF MS has been utilized as a reliable and rapid tool for microbial fingerprinting at the genus and species levels. …
Article scientifique
Genetic parameters of reproductive traits in Tunisian Holsteins
Abstract. Multi-trait Bayesian procedure was used to estimate genetic parameters for reproductive traits in Tunisian Holstein cows. A total of …
Article scientifique
Prevalence of Listeria species in some foods and their rapid identification
Purpose: To investigate the occurrence of Listeria spp., (particularly L. monocytogenes), in different foods and to compare diagnostic tools for …
Article scientifique
Analysis of loco-regional and distant recurrences in breast cancer after conservative surgery
BACKGROUND: A number of patients treated conservatively for breast cancer will develop loco-regional and distant recurrences. Our aim was to …
Article scientifique
Isoeugenol is a selective potentiator of camptothecin cytotoxicity in vertebrate cells lacking TDP1
Camptothecin (CPT), a topoisomerase I (TOP1) inhibitor, exhibits anti-tumor activity against a wide range of tumors. Redundancy of TOP1-mediated repair …
Article scientifique
The Lake Chad Basin, an Isolated and Persistent Reservoir of Vibrio cholerae O1: A Genomic Insight into the Outbreak in Cameroon, 2010
The prevalence of reported cholera was relatively low around the Lake Chad basin until 1991. Since then, cholera outbreaks have …
Article scientifique
The transition from evolutionary stability to branching: A catastrophic evolutionary shift
Evolutionary branching-resident-mutant coexistence under disruptive selection-is one of the main contributions of Adaptive Dynamics (AD), the mathematical framework introduced by …
Article scientifique
The Geobacillus Pan-Genome: Implications for the Evolution of the Genus
The genus Geobacillus is comprised of a diverse group of spore-forming Gram-positive thermophilic bacterial species and is well known for …
Article scientifique
Molecular Epidemiology and Antibiotic Susceptibility of Vibrio cholerae Associated with a Large Cholera Outbreak in Ghana in 2014
BACKGROUND: Ghana is affected by regular cholera epidemics and an annual average of 3,066 cases since 2000. In 2014, Ghana …
Article scientifique
Flashy flagella: flagellin modification is relatively common and highly versatile among the Enterobacteriaceae
BACKGROUND: Post-translational glycosylation of the flagellin protein is relatively common among Gram-negative bacteria, and has been linked to several phenotypes, …
Article scientifique
Cholera Incidence and Mortality in Sub-Saharan African Sites during Multi-country Surveillance
BACKGROUND: Cholera burden in Africa remains unknown, often because of weak national surveillance systems. We analyzed data from the African …