4595
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25307
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Biologie synthétique
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Publications
4595 publication(s) trouvée(s)
Article scientifique
Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair
Histone demethylases have recently gained interest as potential targets in cancer treatment and several histone demethylases have been implicated in …
Article scientifique
DNA barcoding of Clarias gariepinus, Coptodon zillii and Sarotherodon melanotheron from Southwestern Nigeria
DNA barcoding has been adopted as a gold standard rapid, precise and unifying identification system for animal species and provides …
Article scientifique
Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosis
There is an urgent need to identify new treatments for tuberculosis (TB), a major infectious disease caused by Mycobacterium tuberculosis …
Article scientifique
Neonatal infections with multidrug-resistant ESBL-producing E. cloacae and K. pneumoniae in Neonatal Units of two different Hospitals in Antananarivo, Madagascar
BACKGROUND: We investigated the molecular mechanism of ß-lactam resistance in extended-spectrum ß-lactamase (ESBL)-producing Enterobacterial strains isolated in neonatal units of …
Article scientifique
Identification of two new keratinolytic proteases from a Bacillus pumilus strain using protein analysis and gene sequencing
The Bacillus strain (CCUG 66887) has a high capacity to excrete keratinase with the ability to degrade both alpha- and …
Article scientifique
Differential RNA-seq, Multi-Network Analysis and Metabolic Regulation Analysis of Kluyveromyces marxianus Reveals a Compartmentalised Response to Xylose
We investigated the transcriptomic response of a new strain of the yeast Kluyveromyces marxianus, in glucose and xylose media using …
Article scientifique
IMA Genome-F 6
The genomes of Armillaria fuscipes, Ceratocystiopsis minuta, Ceratocystis adiposa, Endoconidiophora laricicola, E. polonica, and Penicillium freii DAOMC 242723 are presented …
Article scientifique
A phylogenetic revision of Penicillium sect. Exilicaulis, including nine new species from fynbos in South Africa
A survey of the fynbos biome in South Africa resulted in the isolation of 61 Penicillium species from Protea repens …
Article scientifique
Intron Derived Size Polymorphism in the Mitochondrial Genomes of Closely Related Chrysoporthe Species
In this study, the complete mitochondrial (mt) genomes of Chrysoporthe austroafricana (190,834 bp), C. cubensis (89,084 bp) and C. deuterocubensis …
Article scientifique
Designing, construction and characterization of genetically encoded FRET-based nanosensor for real time monitoring of lysine flux in living cells
BACKGROUND: Engineering microorganisms in order to improve the metabolite flux needs a detailed knowledge of the concentrations and flux rates …
Article scientifique
A case of fatal Type I congenital disorders of glycosylation (CDG I) associated with low dehydrodolichol diphosphate synthase (DHDDS) activity
BACKGROUND: Type I congenital disorders of glycosylation (CDG-I) are mostly complex multisystemic diseases associated with hypoglycosylated serum glycoproteins. A subgroup …
Article scientifique
Efficient production of acetoin in Saccharomyces cerevisiae by disruption of 2,3-butanediol dehydrogenase and expression of NADH oxidase
Acetoin is widely used in food and cosmetic industry as taste and fragrance enhancer. For acetoin production in this study, …
Article scientifique
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus
BACKGROUND: Multiple recent genome-wide association studies (GWAS) have identified a single nucleotide polymorphism (SNP), rs10771399, at 12p11 that is associated …
Article scientifique
Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis
ATP-binding cassette transporter A1 (ABCA1) plays a critical role in maintaining cellular cholesterol homeostasis. The purpose of this study is …
Article scientifique
Association mapping for cold tolerance in two large maize inbred panels
BACKGROUND: Breeding for cold tolerance in maize promises to allow increasing growth area and production in temperate zones. The objective …
Article scientifique
Cross-Border Cholera Outbreaks in Sub-Saharan Africa, the Mystery behind the Silent Illness: What Needs to Be Done?
INTRODUCTION: Cross-border cholera outbreaks are a major public health problem in Sub-Saharan Africa contributing to the high annual reported cholera …
Article scientifique
The Indris Have Got Rhythm! Timing and Pitch Variation of a Primate Song Examined between Sexes and Age Classes
A crucial, common feature of speech and music is that they show non-random structures over time. It is an open …
Article scientifique
Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood
Puberty marks numerous physiological processes which are initiated by central activation of the hypothalamic-pituitary-gonadal axis, followed by development of secondary …
Article scientifique
Recommendations for competing sexual-asexually typified generic names in Sordariomycetes (except Diaporthales, Hypocreales, and Magnaporthales)
With the advance to one scientific name for each fungal species, the generic names in the class Sordariomycetes typified by …
Article scientifique
Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome
To investigate large structural clonal mosaicism of chromosome X, we analysed the SNP microarray intensity data of 38,303 women from …