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Publications
3646 publication(s) trouvée(s)
Article scientifique
Short- and long-term humoral immune response against Yersinia pestis in plague patients, Madagascar
BACKGROUND: Plague, a fatal disease caused by the bacillus, Yersinia pestis, still affects resources-limited countries. Information on antibody response to …
Article scientifique
Ameliorative and anti-arthritic potential of arjunolic acid against complete Freund’s adjuvant-induced arthritis in rats
Purpose: To determine the anti-arthritic effect of arjunolic acid against complete Freund’s adjuvant (CFA)-induced arthritis in rats.Methods: Arthritis was induced …
Article scientifique
Esomeprazole improves the acidic microenvironment of epithelial ovarian cancer by inhibiting the expression of VATPase
Purpose: To determine the effect of esomeprazole on apoptosis of ovarian cancer cells and their sensitivity to paclitaxel, and the …
Article scientifique
MiR-28-3p enhances healing of fracture via negative regulation of the target gene Sox6 and activation of PI3K/Akt signaling pathway
Purpose: To investigate the effect of miR-28-3p on fracture healing, and the involvement of Sox6 gene and PI3K/Akt signaling pathway …
Article scientifique
Estimating the basic reproduction number for the 2015 bubonic plague outbreak in Nyimba district of Eastern Zambia
BACKGROUND: Plague is a re-emerging flea-borne infectious disease of global importance and in recent years, Zambia has periodically experienced increased …
Article scientifique
Role of Napsin A and Survivin Immunohistochemical Expression in Bronchogenic Adenocarcinoma
BACKGROUND: Lung cancer, being the leading cause of cancer deaths with most patients diagnosed at a late stage, represents a …
Article scientifique
Significance of Some Non-Invasive Biomarkers in the Early Diagnosis and Staging of Egyptian Breast Cancer Patients
INTRODUCTION: Breast cancer is one of the most relevant malignancies among women. Early diagnosis and accurate staging of breast cancer …
Article scientifique
AKT1 Polymorphism (rs10138227) and Risk of Colorectal Cancer in Moroccan Population: A Case Control Study
BACKGROUND: LMTK3 and AKT1 each have a role in carcinogenesis and tumor progression. The analysis of single nucleotide polymorphisms of …
Article scientifique
Survival and growth of Vibrio cholerae and Escherichia coli in treated groundwater consumed in northern Cameroon
Abstract Treated groundwater is a major source of drinking water but subject to potential contamination of fecal–oral pathogens. To understand …
Article scientifique
Senescence of song revealed by a long-term study of the Seychelles warbler (Acrocephalus sechellensis)
Senescence is widespread in nature, often resulting in diminishing survival or reproduction with age, but its role in age-dependent variation …
Article scientifique
Expression of microRNA-181a and microRNA-196b in Egyptian Pediatric acute Lymphoblastic Leukemia
BACKGROUND: Differential expression of miRNA provides important insights into pathogenesis of cancer including leukemia. Deregulation of microRNA may contribute to …
Article scientifique
DNA Methyltransferases as Potential Biomarkers for HCV Related Hepatocellular Carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) is a major health concern in many countries including Egypt. The alteration in DNA methylation that …
Article scientifique
Saussurea lappa Clarke extract exhibits potent antioxidant effect and attenuates neuroinflammatory responses in lipopolysaccharide-stimulated microglial cells
Purpose: To investigate the antioxidant and anti-neuroinflammatory potential of Saussurea lappa Clarke (SLC-EA) extract in LPS-stimulated BV-2 microglial cells.Methods: Cell …
Article scientifique
Prevalence of plasmid-mediated AmpC beta-lactamases in Enterobacteria isolated from urban and rural folks in Uganda
Background : AmpC beta-lactamase-producing bacteria are associated with increased resistance to third-generation cephalosporins. Here, we describe plasmid-mediated AmpC beta-lactamase-producing enterobacteria …
Article scientifique
Discovering novel driver mutations from pan-cancer analysis of mutational and gene expression profiles
As the genomic profile across cancers varies from person to person, patient prognosis and treatment may differ based on the …
Article scientifique
Functional characterisation of the transcriptome from leaf tissue of the fluoroacetate-producing plant, Dichapetalum cymosum, in response to mechanical wounding
Dichapetalum cymosum produces the toxic fluorinated metabolite, fluoroacetate, presumably as a defence mechanism. Given the rarity of fluorinated metabolites in …
Article scientifique
In silico design and validation of a highly degenerate primer pair: a systematic approach
BACKGROUND: The techniques of amplifying genetic materials have enabled the extensive study of several biological activities outside the biological milieu …
Article scientifique
Tamoxifen induces hypercoagulation and alterations in ERα and ERβ dependent on breast cancer sub-phenotype ex vivo
Tamoxifen shows efficacy in reducing breast cancer-related mortality but clinically, is associated with increased risk for thromboembolic events. We aimed …
Article scientifique
Characterisation of plasmodial transketolases and identification of potential inhibitors: an in silico study
BACKGROUND: Plasmodial transketolase (PTKT) enzyme is one of the novel pharmacological targets being explored as potential anti-malarial drug target due …
Article scientifique
Western influenced lifestyle and Kv2.1 association as predicted biomarkers for Tunisian colorectal cancer
BACKGROUND: Colorectal cancer (CRC) is the third most diagnosed malignancy worldwide. The global burden is expected to increase along with …