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Publications
4601 publication(s) trouvée(s)
Article scientifique
Peer Review Report For: Transcription factor motif quality assessment requires systematic comparative analysis [version 2; peer review: 2 approved]
Transcription factor (TF) binding site prediction remains a challenge in gene regulatory research due to degeneracy and potential variability in …
Article scientifique
A game for crowdsourcing the segmentation of BigBrain data
The BigBrain, a high-resolution 3-D model of a human brain at nearly cellular resolution, is the best brain imaging data …
Article scientifique
Novel chloroquinoline derivatives incorporating biologically active benzenesulfonamide moiety: synthesis, cytotoxic activity and molecular docking
BACKGROUND: Quinoline derivatives have diverse biological activities including anticancer activity. On the other hand, many sulfonamide derivatives exhibited good cytotoxic …
Article scientifique
Evaluation of Anti-tumor and Chemoresistance-lowering Effects of Pectolinarigenin from Cirsium japonicum Fisch ex DC in Breast Cancer
Purpose: To investigate the antitumor and chemoresistance-lowering effects of pectolinarigenin on breast cancer cells.Methods: Pectolinarigenin was purified by a combination …
Article scientifique
Effect of Interaction of Methanol Leaf Extract of Spondias mombin (Linn) and Amoxicillin on Some Diarrheagenic Escherichia coli
Purpose: To study the effect of interaction between methanol leaf extract of Spondias mombin and amoxicillin on diarrheagenic Escherichia coli …
Article scientifique
Fluorescence imaging of in vivo miR-124a-induced neurogenesis of neuronal progenitor cells using neuron-specific reporters
BACKGROUND: Facilitation of the differentiation of the stem cells toward neuronal lineage is crucial for enhancing the differentiation efficacy of …
Article scientifique
Metabolome response to temperature-induced virulence gene expression in two genotypes of pathogenic Vibrio parahaemolyticus
BACKGROUND: Vibrio parahaemolyticus is a main causative agent of serious human seafood-borne gastroenteritis disease. Many researchers have investigated its pathogenesis …
Article scientifique
Clinical and pathological features of BRCA1/2 tumors in a sample of high-risk Moroccan breast cancer patients
BACKGROUND: BRCA1 and BRCA2 genes explain a large part of hereditary breast cancer. Several studies have shown that BRCA1 and …
Article scientifique
Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets
Research focusing on type 1 diabetes (T1D) autoantigens aims to explore our understanding of these beta cell proteins in order …
Article scientifique
An exploratory study of volumetric analysis for assessing tumor response with 18F-FAZA PET/CT in patients with advanced non-small-cell lung cancer (NSCLC)
BACKGROUND: Hypoxia is associated with resistance to chemotherapy and radiotherapy and is randomly distributed within malignancies. Characterization of changes in …
Article scientifique
Evaluation of the OvineSNP50 chip for use in four South African sheep breeds
Relatively rapid and cost-effective genotyping using the OvineSNP50 chip holds great promise for the South African sheep industry and research …
Article scientifique
Aspergillus Oryzae S2 α-Amylase Domain C Involvement in Activity and Specificity: In Vivo Proteolysis, Molecular and Docking Studies
We previously reported that Aspergillus oryzae strain S2 had produced two α-amylase isoforms named AmyA and AmyB. The apparent molecular …
Article scientifique
Determination of Phytochemical Compounds, and Tyrosinase Inhibitory and Antimicrobial Activities of Bioactive Compounds from Streblus ilicifolius (S Vidal) Corner
Purpose: To determine the phytochemical content, and tyrosinase inhibitory and antimicrobial activities of the wood from Streblus ilicifolius (S. Vidal) …
Article scientifique
Design, synthesis and anticancer activity of some novel thioureido-benzenesulfonamides incorporated biologically active moieties
BACKGROUND: Many thiourea derivatives have exhibited biological activities including anticancer activity through several mechanisms. On the other hand, benzenesulfonamide derivatives …
Article scientifique
Proteogenomic Analysis of Mycobacterium smegmatis Using High Resolution Mass Spectrometry
Biochemical evidence is vital for accurate genome annotation. The integration of experimental data collected at the proteome level using high …
Article scientifique
Polymorphisms of Estrogen Metabolism-Related Genes and Prostate Cancer Risk in Two Populations of African Ancestry
BACKGROUND: Estrogens are thought to play a critical role in prostate carcinogenesis. It has been suggested that polymorphisms of genes …
Article scientifique
The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined
Over the past two decades, huge amounts of research were launched to understand the functions of sphingosine. Many pathways were …
Article scientifique
Small Non-coding RNAs Associated with Viral Infectious Diseases of Veterinary Importance: Potential Clinical Applications
MicroRNAs (miRNAs) represent a class of small non-coding RNA (sncRNA) molecules that can regulate mRNAs by inducing their degradation or …
Article scientifique
Structured feature selection using coordinate descent optimization
BACKGROUND: Existing feature selection methods typically do not consider prior knowledge in the form of structural relationships among features. In …
Article scientifique
Association of MicroRNA-196a2 Variant with Response to Short-Acting β2-Agonist in COPD: An Egyptian Pilot Study
Chronic obstructive pulmonary disease (COPD) is a multifactorial chronic respiratory disease, characterized by an obstructive pattern. Understanding the genetic predisposition …