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Publications
4601 publication(s) trouvée(s)
Article scientifique
The Lake Chad Basin, an Isolated and Persistent Reservoir of Vibrio cholerae O1: A Genomic Insight into the Outbreak in Cameroon, 2010
The prevalence of reported cholera was relatively low around the Lake Chad basin until 1991. Since then, cholera outbreaks have …
Article scientifique
The transition from evolutionary stability to branching: A catastrophic evolutionary shift
Evolutionary branching-resident-mutant coexistence under disruptive selection-is one of the main contributions of Adaptive Dynamics (AD), the mathematical framework introduced by …
Article scientifique
The Geobacillus Pan-Genome: Implications for the Evolution of the Genus
The genus Geobacillus is comprised of a diverse group of spore-forming Gram-positive thermophilic bacterial species and is well known for …
Article scientifique
Molecular Epidemiology and Antibiotic Susceptibility of Vibrio cholerae Associated with a Large Cholera Outbreak in Ghana in 2014
BACKGROUND: Ghana is affected by regular cholera epidemics and an annual average of 3,066 cases since 2000. In 2014, Ghana …
Article scientifique
Flashy flagella: flagellin modification is relatively common and highly versatile among the Enterobacteriaceae
BACKGROUND: Post-translational glycosylation of the flagellin protein is relatively common among Gram-negative bacteria, and has been linked to several phenotypes, …
Article scientifique
Cholera Incidence and Mortality in Sub-Saharan African Sites during Multi-country Surveillance
BACKGROUND: Cholera burden in Africa remains unknown, often because of weak national surveillance systems. We analyzed data from the African …
Article scientifique
Fungal Genomics Challenges the Dogma of Name-Based Biosecurity
Microorganisms have inadvertently been spread via the global movement and trade of their substrates, such as animals, plants, and soil.This …
Article scientifique
Genetic characterization of TEM-type ESBL-associated antibacterial resistance in Enterobacteriaceae in a tertiary hospital in Ghana
BACKGROUND: Antibiotic resistance due to the presence of extended-spectrum beta-lactamases (ESBLs) among Enterobacteriaceae is a worldwide problem. Data from Ghana …
Article scientifique
Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model
BACKGROUND: Gene-based virotherapy mediated by oncolytic viruses is currently experiencing a renaissance in cancer therapy. However, relatively little attention has …
Article scientifique
The Novel Gene VpPR4-1 from Vitis pseudoreticulata Increases Powdery Mildew Resistance in Transgenic Vitis vinifera L.
Pathogenesis-related proteins (PRs) can lead to increased resistance of the whole plant to pathogen attack. Here, we isolate and characterize …
Article scientifique
Glycosyltransferase Gene Expression Profiles Classify Cancer Types and Propose Prognostic Subtypes
Aberrant glycosylation in tumours stem from altered glycosyltransferase (GT) gene expression but can the expression profiles of these signature genes …
Article scientifique
A European Mitochondrial Haplotype Identified in Ancient Phoenician Remains from Carthage, North Africa
While Phoenician culture and trade networks had a significant impact on Western civilizations, we know little about the Phoenicians themselves. …
Article scientifique
Genetic Diversity and Population Structure in South African, French and Argentinian Angora Goats from Genome-Wide SNP Data
The Angora goat populations in Argentina (AR), France (FR) and South Africa (SA) have been kept geographically and genetically distinct. …
Article scientifique
Circulating Serum miRNAs as Diagnostic Markers for Colorectal Cancer
AIM: The study was designed to assess the possibility of using circulating miRNAs (serum miRNAs) as diagnostic biomarkers in colorectal …
Article scientifique
Quorum Sensing Inhibiting Activity of Streptomyces coelicoflavus Isolated from Soil
Quorum sensing (QS) systems communicate bacterial population and stimulate microbial pathogenesis through signaling molecules. Inhibition of QS signals potentially suppresses …
Article scientifique
Meta-analysis of proportion estimates of Extended-Spectrum-Beta-Lactamase-producing Enterobacteriaceae in East Africa hospitals
BACKGROUND: A high proportion of Extended-Spectrum-Beta-Lactamase (ESBL) producing Enterobacteriaceae is causing common infections in all regions of the world. The …
Article scientifique
microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection
Breast cancer (BC) is the most common cancer type and the second cause of cancer-related death among women. Therefore, better …
Article scientifique
ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan
Mutations in genes required for the glycosylation of α-dystroglycan lead to muscle and brain diseases known as dystroglycanopathies. However, the …
Article scientifique
Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database
With more than 30,000 species, ray-finned fish represent approximately half of vertebrates. The evolution of ray-finned fish was impacted by …
Article scientifique
Detection of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli in Market-Ready Chickens in Zambia
The frequent administering of antibiotics in the treatment of poultry diseases may contribute to emergence of antimicrobialresistant strains. The objective …