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Publications
4592 publication(s) trouvée(s)
Article scientifique
Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation
Prolyl hydroxylase domain protein 2 (PHD2) belongs to an evolutionarily conserved superfamily of 2-oxoglutarate and Fe(II)-dependent dioxygenases that mediates homeostatic …
Article scientifique
H3Africa AWI-Gen Collaborative Centre: a resource to study the interplay between genomic and environmental risk factors for cardiometabolic diseases in four sub-Saharan African countries
Africa is experiencing a rapid increase in adult obesity and associated cardiometabolic diseases (CMDs). The H3Africa AWI-Gen Collaborative Centre was …
Article scientifique
Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.
Recent advances have shown that the abnormal inflammatory response observed in CD involves an interplay among intestinal microbiota, host genetics …
Article scientifique
ecancermedicalscience
The immunohistochemical (IHC) subtyping of breast cancer can be a useful substitute for gene expression analysis. The aim of this …
Article scientifique
Microcanonical Annealing and Threshold Accepting for Parameter Determination and Feature Selection of Support Vector Machines
Support vector machine (SVM) is a popular classification technique with many diverse applications. Parameter determination and feature selection significantly influences …
Article scientifique
Growth differentiation factor 9 gene variants in Sudanese desert sheep ecotypes
Certain variants in the growth differentiation factor 9 (GDF9) gene have major effects on the ovulation rate in sheep. The …
Article scientifique
A Pseudomonas Protegens with High Antifungal Activity Protects Apple Fruits Against Botrytis Cinerea Gray Mold
Using beneficial bacteria to control plant pathogens has become an ecofriendly alternative to the excessive use of chemicals. In this …
Article scientifique
Semilobar holoprosencephaly in a 12-month-old baby boy born to a primigravida patient with type 1 diabetes mellitus: a case report
BACKGROUND: Holoprosencephaly is a rare spectrum of cephalic disorders resulting from a failure or incomplete division of the embryonic forebrain …
Article scientifique
Localization and Transcriptional Responses of Chrysoporthe austroafricana in Eucalyptus grandis Identify Putative Pathogenicity Factors
Chrysoporthe austroafricana is a fungal pathogen that causes the development of stem cankers on susceptible Eucalyptus grandis trees. Clones of …
Article scientifique
Alkaline protease from a new halotolerant alkaliphilic Bacillus agaradhaerens strain ak-r isolated from egyptian soda lakes
Alkaline proteases are hydrolytic enzymes that cleave peptide bonds in proteins and peptides in alkaline conditions, which occupy a pivotal …
Article scientifique
Tracing back ancient oral microbiomes and oral pathogens using dental pulps from ancient teeth
Ancient dental pulps are highly precious samples because they conserve DNA from humans and blood-borne pathogens for ages. However, little …
Article scientifique
The Effects of Transdermally Delivered Oleanolic Acid on Malaria Parasites and Blood Glucose Homeostasis in P. berghei-Infected Male Sprague-Dawley Rats
The present study investigated the effects of transdermally delivered oleanolic acid (OA) monotherapy and in combination with chloroquine (CHQ) on …
Article scientifique
A fast exact sequential algorithm for the partial digest problem
BACKGROUND: Restriction site analysis involves determining the locations of restriction sites after the process of digestion by reconstructing their positions …
Article scientifique
Functional and structural characterization of a novel putative cysteine protease cell wall-modifying multi-domain enzyme selected from a microbial metagenome
Abstract A current metagenomics focus is to interpret and transform collected genomic data into biological information. By combining structural, functional …
Article scientifique
Acthaside: a new chromone derivative from Acacia ataxacantha and its biological activities
Acacia ataxacantha (Fabaceae), used in traditional medicine grows in the South-West of Bénin. Ethyl acetate extract of the barks of …
Article scientifique
Genome and Proteome Analysis of Rhodococcus erythropolis MI2: Elucidation of the 4,4´-Dithiodibutyric Acid Catabolism
Rhodococcus erythropolis MI2 has the extraordinary ability to utilize the xenobiotic 4,4´-dithiodibutyric acid (DTDB). Cleavage of DTDB by the disulfide-reductase …
Article scientifique
Pinoresinol diglucoside exhibits protective effect on dexamethasone-induced osteoporosis in rats
Purpose: To investigate the effect of pinoresinol diglucoside (PDG) on dexamethasone-induced osteoporosis in rats.Methods: Sixty Wistar rats were randomly and …
Article scientifique
A Novel Non-Cumbersome Approach Towards Biosynthesis of Pectic-Oligosaccharides by Non-Aflatoxigenic Aspergillus sp. Section Flavi Strain EGY1 DSM 101520 through Citrus Pectin Fermentation
Pectic-Oligosaccharides (POS) have a growing potential in food and feed industries. To satisfy the demand of worldwide markets from POS …
Article scientifique
Tbx5 Buffers Inherent Left/Right Asymmetry Ensuring Symmetric Forelimb Formation
The forelimbs and hindlimbs of vertebrates are bilaterally symmetric. The mechanisms that ensure symmetric limb formation are unknown but they …
Article scientifique
The role of the unusual threonine string in the conversion of prion protein
Abstract The conversion of normal prion protein (PrP) into pathogenic PrP conformers is central to prion disease, but the mechanism …