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Publications
4592 publication(s) trouvée(s)
Article scientifique
Altered Cell to Cell Communication, Autophagy and Mitochondrial Dysfunction in a Model of Hepatocellular Carcinoma: Potential Protective Effects of Curcumin and Stem Cell Therapy
BACKGROUND: Hepato-carcinogenesis is multifaceted in its molecular aspects. Among the interplaying agents are altered gap junctions, the proteasome/autophagy system, and …
Article scientifique
H3Africa multi-centre study of the prevalence and environmental and genetic determinants of type 2 diabetes in sub-Saharan Africa: study protocol
The burden and aetiology of type 2 diabetes (T2D) and its microvascular complications may be influenced by varying behavioural and …
Article scientifique
Evaluation in Cameroon of a Novel, Simplified Methodology to Assist Molecular Microbiological Analysis of V. cholerae in Resource-Limited Settings
BACKGROUND: Vibrio cholerae is endemic in South Asia and Africa where outbreaks of cholera occur widely and are particularly associated …
Article scientifique
Discovery and profiling of small RNAs responsive to stress conditions in the plant pathogen Pectobacterium atrosepticum
BACKGROUND: Small RNAs (sRNAs) have emerged as important regulatory molecules and have been studied in several bacteria. However, to date, …
Article scientifique
Liver Label Retaining Cancer Cells Are Relatively Resistant to the Reported Anti-Cancer Stem Cell Drug Metformin
BACKGROUND & AIMS: Recently, we reported that liver Label Retaining Cancer Cells (LRCC) can initiate tumors with only 10 cells …
Article scientifique
Genetic diversity of lactase persistence in East African populations
BACKGROUND: The expression of lactase which digests lactose from milk in humans is generally lost after weaning, but selected mutations …
Article scientifique
Diffany: an ontology-driven framework to infer, visualise and analyse differential molecular networks
BACKGROUND: Differential networks have recently been introduced as a powerful way to study the dynamic rewiring capabilities of an interactome …
Article scientifique
Multivalent Targeting Based Delivery of Therapeutic Peptide using AP1-ELP Carrier for Effective Cancer Therapy
Elastin-like polypeptide (ELP)-based drug delivery has been utilized for various applications including cancer therapies for many years. Genetic incorporation of …
Article scientifique
Plasma Circulating Cell-free Nuclear and Mitochondrial DNA as Potential Biomarkers in the Peripheral Blood of Breast Cancer Patients
BACKGROUND: In Egypt, breast cancer is estimated to be the most common cancer among females. It is also a leading …
Article scientifique
TRAPLINE: a standardized and automated pipeline for RNA sequencing data analysis, evaluation and annotation
BACKGROUND: Technical advances in Next Generation Sequencing (NGS) provide a means to acquire deeper insights into cellular functions. The lack …
Article scientifique
Gut Microbiota in Children Hospitalized with Oedematous and Non-Oedematous Severe Acute Malnutrition in Uganda
BACKGROUND: Severe acute malnutrition (SAM) among children remains a major health problem in many developing countries. SAM manifests in both …
Article scientifique
Intrigues of biofilm: A perspective in veterinary medicine
Biofilm has a tremendous impact in the field of veterinary medicine, especially the livestock industry, leading to a serious economic …
Article scientifique
The Eucalyptus grandis NBS-LRR Gene Family: Physical Clustering and Expression Hotspots
Eucalyptus grandis is a commercially important hardwood species and is known to be susceptible to a number of pests and …
Article scientifique
A New Anaesthetic Protocol for Adult Zebrafish (Danio rerio): Propofol Combined with Lidocaine
BACKGROUND: The increasing use of zebrafish model has not been accompanied by the evolution of proper anaesthesia for this species …
Article scientifique
Supplementation with a fish protein hydrolysate (Micromesistius poutassou): effects on body weight, body composition, and CCK/GLP-1 secretion
BACKGROUND: Fish protein hydrolysates (FPHs) have been reported as a suitable source of proteins for human nutrition because of their …
Article scientifique
HYOU1, Regulated by LPLUNC1, Is Up-Regulated in Nasopharyngeal Carcinoma and Associated with Poor Prognosis
OBJECTIVE: This study aims to investigate the roles and mechanisms of long palate, lung and nasal epithelium clone 1 (LPLUNC1) …
Article scientifique
Prevalence and characterization of extended-spectrum beta-lactamases producing Enterobacteriaceae in healthy children and associated risk factors
BACKGROUND: Community acquired infections due to extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) had been increased. The fecal flora of children in the …
Article scientifique
Identification of Algerian Field-Caught Phlebotomine Sand Fly Vectors by MALDI-TOF MS
BACKGROUND: Phlebotomine sand flies are known to transmit Leishmania parasites, bacteria and viruses that affect humans and animals in many …
Article scientifique
CoExpNetViz: Comparative Co-Expression Networks Construction and Visualization Tool
MOTIVATION: Comparative transcriptomics is a common approach in functional gene discovery efforts. It allows for finding conserved co-expression patterns between …
Article scientifique
MicroRNA-26a suppresses epithelial-mesenchymal transition in human hepatocellular carcinoma by repressing enhancer of zeste homolog 2
BACKGROUND: Our previous study reported that microRNA-26a (miR-26a) inhibited tumor progression by inhibiting tumor angiogenesis and intratumoral macrophage infiltration in …