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Publications
4592 publication(s) trouvée(s)
Article scientifique
The Fab Fragment of a Human Anti-Siglec-9 Monoclonal Antibody Suppresses LPS-Induced Inflammatory Responses in Human Macrophages
Sepsis is a major cause of death for hospitalized patients and is characterized by massive overreaction of immune responses to …
Article scientifique
Contribution towards a Metabolite Profile of the Detoxification of Benzoic Acid through Glycine Conjugation: An Intervention Study
Benzoic acid is widely used as a preservative in food products and is detoxified in humans through glycine conjugation. Different …
Article scientifique
Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic
HIV molecular epidemiology studies analyse viral pol gene sequences due to their availability, but whole genome sequencing allows to use …
Article scientifique
Detecting the existence of gene flow between Spanish and North African goats through a coalescent approach
Abstract Human-driven migrations are one of the main processes shaping the genetic diversity and population structure of domestic species. However, …
Article scientifique
Production of Phloroglucinol, a Platform Chemical, in Arabidopsis using a Bacterial Gene
Phloroglucinol (1,3,5-trihydroxybenzene; PG) and its derivatives are phenolic compounds that are used for various industrial applications. Current methods to synthesize …
Article scientifique
Poor Compliance to Hormone Therapy and Decreased Bone Mineral Density in Women with Premature Ovarian Insufficiency
Premature ovarian insufficiency leads to through infertility and estrogen deficiency. Optimal management encompasses estrogen replacement therapy. Long-term outcome of women …
Article scientifique
In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin
BACKGROUND: The emergence of artemisinin-resistant Plasmodium falciparum strains poses a serious challenge to the control of malaria. This necessitates the …
Article scientifique
Characterisation of Commensal Escherichia coli Isolated from Apparently Healthy Cattle and Their Attendants in Tanzania
While pathogenic types of Escherichia coli are well characterized, relatively little is known about the commensal E. coli flora. In …
Article scientifique
Potential for Nitrogen Fixation in the Fungus-Growing Termite Symbiosis
Termites host a gut microbiota of diverse and essential symbionts that enable specialization on dead plant material; an abundant, but …
Article scientifique
Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis
Treatment for human African trypanosomiasis is dependent on the species of trypanosome causing the disease and the stage of the …
Article scientifique
Cholera Rapid Test with Enrichment Step Has Diagnostic Performance Equivalent to Culture
Cholera rapid diagnostic tests (RDT) could play a central role in outbreak detection and surveillance in low-resource settings, but their …
Article scientifique
RNA interference: a promising biopesticide strategy against the African Sweetpotato Weevil Cylas brunneus
The African sweetpotato weevil Cylas brunneus is one of the most devastating pests affecting the production of sweetpotatoes, an important …
Article scientifique
The ace-1 Locus Is Amplified in All Resistant Anopheles gambiae Mosquitoes: Fitness Consequences of Homogeneous and Heterogeneous Duplications
Gene copy-number variations are widespread in natural populations, but investigating their phenotypic consequences requires contemporary duplications under selection. Such duplications …
Article scientifique
MicroRNA and Transcription Factor Gene Regulatory Network Analysis Reveals Key Regulatory Elements Associated with Prostate Cancer Progression
Technological and methodological advances in multi-omics data generation and integration approaches help elucidate genetic features of complex biological traits and …
Article scientifique
High Expression of LINC01420 indicates an unfavorable prognosis and modulates cell migration and invasion in nasopharyngeal carcinoma
Recent studies demonstrated that long non-coding RNAs (lncRNAs) deregulated in many cancer tissues including nasopharyngeal carcinoma (NPC) and had critical …
Article scientifique
Revealing hidden species diversity in closely related species using nuclear SNPs, SSRs and DNA sequences – a case study in the tree genus Milicia
BACKGROUND: Species delimitation in closely related plant taxa can be challenging because (i) reproductive barriers are not always congruent with …
Article scientifique
Melatonin Increases the Chilling Tolerance of Chloroplast in Cucumber Seedlings by Regulating Photosynthetic Electron Flux and the Ascorbate-Glutathione Cycle
The aim of the study was to monitor the effects of exogenous melatonin on cucumber (Cucumis sativus L.) chloroplasts and …
Article scientifique
High Prevalence of Faecal Carriage of ESBL-Producing Enterobacteriaceae among Children in Dar es Salaam, Tanzania
BACKGROUND: Faecal carriage of ESBL-producing bacteria is a potential risk for transmission and infection. Little is known about faecal carriage …
Article scientifique
Molecular typing and virulence analysis of multidrug resistant Klebsiella pneumoniae clinical isolates recovered from Egyptian hospitals
Klebsiella pneumonia infection rates have increased dramatically. Molecular typing and virulence analysis are powerful tools that can shed light on …
Article scientifique
STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer
STAT3 signaling plays the pivotal role in tumorigenesis through EZH2 epigenetic modification, which enhanced STAT3 activity by increased tyrosine phosphorylation …