2427
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Publications
2427 publication(s) trouvée(s)
Article scientifique
Modulation of the Endothelin System in Colorectal Cancer Liver Metastasis: Influence of Epigenetic Mechanisms?
Targeting of endothelin system genes is a promising strategy in cancer therapy. The modulation of these genes was explored in …
Article scientifique
Patterns of genetic diversity in North Africa: Moroccan-Algerian genetic split in Juniperus thurifera subsp. africana
Juniperus thurifera is a key element of the forest communities in arid and semi-arid areas of the western Mediterranean. Previous …
Article scientifique
Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells
Salmonella typhimurium VNP-20009 (VNP) is a non-pathogenic attenuated strain, which, as a facultative anaerobe, preferentially accumulates in hypoxic regions of …
Article scientifique
Pioneering Informed Consent for Return of Research Results to Breast Cancer Patients Facing Barriers to Implementation of Genomic Medicine: The Kenyan BRCA1/2 Testing Experience Using Whole Exome Sequencing
Introduction: Obtaining informed consent from study participants and disseminating the findings responsibly is a key principle required for ethically conducted …
Article scientifique
Afro-alpine flagships revisited: Parallel adaptation, intermountain admixture and shallow genetic structuring in the giant senecios (Dendrosenecio)
Distantly related lineages of the enigmatic giant rosette plants of tropical alpine environments provide classical examples of convergent adaptation. For …
Article scientifique
The atlas of StW 573 and the late emergence of human-like head mobility and brain metabolism
Functional morphology of the atlas reflects multiple aspects of an organism's biology. More specifically, its shape indicates patterns of head …
Article scientifique
Genotypic characterization of multiple drug resistant Escherichia coli isolates from a pediatric cancer hospital in Egypt
Infection with multiple drug resistant (MDR) Escherichia coli poses a life threat to immunocompromised pediatric cancer patients. Our aim is …
Article scientifique
Glutathione S-transferase M1 and T1 genes deletion polymorphisms and risk of developing essential hypertension: a case-control study in Burkina Faso population (West Africa)
Abstract Background Glutathione S-transferases play a key role in the detoxification of persistent oxidative stress products which are one of …
Article scientifique
Cytogenetics of entelegyne spiders (Arachnida, Araneae) from southern Africa
Spiders represent one of the most studied arachnid orders. They are particularly intriguing from a cytogenetic point of view, due …
Article scientifique
Oxygen consumption rate of Caenorhabditis elegans as a high-throughput endpoint of toxicity testing using the Seahorse XFe96 Extracellular Flux Analyzer
Abstract Caenorhabditis elegans presents functioning, biologically relevant phenotypes and is frequently used as a bioindicator of toxicity. However, most C. …
Article scientifique
Myeloid-Derived Suppressor Cells as Target of Phosphodiesterase-5 Inhibitors in Host-Directed Therapeutics for Tuberculosis
Resistance towards current and new classes of anti-tuberculosis (TB) antibiotics are emerging rapidly, thus innovative therapies focussed on host processes, …
Article scientifique
A survey of extended-spectrum beta-lactamase-producing Enterobacteriaceae in urban wetlands in southwestern Nigeria as a step towards generating prevalence maps of antimicrobial resistance
In many countries, emission of insufficiently treated wastewater into water bodies appears to be an important factor in spreading clinically …
Article scientifique
Decreased Efficacy of Doxorubicin Corresponds With Modifications in Lipid Metabolism Markers and Fatty Acid Profiles in Breast Tumors From Obese vs. Lean Mice
Breast cancer cells modulate lipid and fatty acid metabolism to sustain proliferation. The role of adipocytes in cancer treatment efficacy …
Article scientifique
Time-Course RNAseq Reveals Exserohilum turcicum Effectors and Pathogenicity Determinants
Exserohilum turcicum (sexual stage Setosphaeria turcica) is the hemibiotrophic causal agent of northern leaf blight of maize and sorghum. This …
Article scientifique
Description of the targeted water supply and hygiene response strategy implemented during the cholera outbreak of 2017–2018 in Kinshasa, DRC
BACKGROUND: Rapid control of cholera outbreaks is a significant challenge in overpopulated urban areas. During late-2017, Kinshasa, the capital of …
Article scientifique
Multi-drug resistant bacteria predict mortality in bloodstream infection in a tertiary setting in Tanzania
BACKGROUND: Bloodstream infections (BSI) are serious and life-threatening, associated with high mortality and morbidity. In resource-limited settings, there is a …
Article scientifique
Three-gene PCR and high-resolution melting analysis for differentiating vertebrate species mitochondrial DNA for biodiversity research and complementing forensic surveillance
Reliable molecular identification of vertebrate species from morphologically unidentifiable tissue is critical for the prosecution of illegally-traded wildlife products, conservation-based …
Article scientifique
Antibiogram and beta-lactamase genes among cefotaxime resistant E. coli from wastewater treatment plant
Abstract Background The World Health Organization (WHO) recently classified Enterobacteriaceae resistance to third-generation cephalosporin into the group of pathogens with …
Article scientifique
Biosafety Regulatory Reviews and Leeway to Operate: Case Studies From Sub-Sahara Africa
While modern biotechnology and, specifically, genetic modification are subject of debate in many parts of the world, an increasing number …
Article scientifique
Emergence of Cronobacter sakazakii in Cases of Neonatal Sepsis in Upper Egypt: First Report in North Africa
Background and aim: Cronobacter sakazakii (C. sakazakii) has attracted considerable attention as an emerging neonatal pathogen and has been associated …