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4595 publication(s) trouvée(s)
Article scientifique
Parent-of-origin effects on genome-wide DNA methylation in the Cape honey bee (Apis mellifera capensis) may be confounded by allele-specific methylation
BACKGROUND: Intersexual genomic conflict sometimes leads to unequal expression of paternal and maternal alleles in offspring, resulting in parent-of-origin effects. …
Article scientifique
Cost-Effectiveness of Antivenoms for Snakebite Envenoming in 16 Countries in West Africa
BACKGROUND: Snakebite poisoning is a significant medical problem in agricultural societies in Sub Saharan Africa. Antivenom (AV) is the standard …
Article scientifique
miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinoma
Bromodomain containing 7 (BRD7) was identified as a nuclear transcriptional regulatory factor. BRD7 functions as a tumor suppressor in multiple …
Article scientifique
Naringin Reduces Hyperglycemia-Induced Cardiac Fibrosis by Relieving Oxidative Stress
INTRODUCTION: Hyperglycemia promotes myocardial fibrotic lesions through upregulation of PKC and p38 in response to redox changes. The effects of …
Article scientifique
Metformin sensitizes sorafenib to inhibit postoperative recurrence and metastasis of hepatocellular carcinoma in orthotopic mouse models
BACKGROUND: Sorafenib is recognized as a standard treatment for advanced hepatocellular carcinoma (HCC). However, many patients have to adopt dose …
Article scientifique
Response of Triple Negative Breast Cancer to Neoadjuvant Chemotherapy: Correlation between Ki-67 Expression and Pathological Response
Triple-negative breast cancers constitute about 15% of all cases, but despite their higher response to neoadjuvant chemotherapy, the tumors are …
Article scientifique
Energy cost and return for hunting in African wild dogs and cheetahs
African wild dogs (Lycaon pictus) are reported to hunt with energetically costly long chase distances. We used high-resolution GPS and …
Article scientifique
Renoprotective Effect of Lactoferrin against Chromium-Induced Acute Kidney Injury in Rats: Involvement of IL-18 and IGF-1 Inhibition
Hexavalent chromium (CrVI) is a heavy metal widely used in more than 50 industries. Nephrotoxicity is a major adverse effect …
Article scientifique
Characterization of an extensive rainbow trout miRNA transcriptome by next generation sequencing
BACKGROUND: MicroRNAs (miRNAs) have emerged as important post-transcriptional regulators of gene expression in a wide variety of physiological processes. They …
Article scientifique
Do little interactions get lost in dark random forests?
BACKGROUND: Random forests have often been claimed to uncover interaction effects. However, if and how interaction effects can be differentiated …
Article scientifique
Umbilical cord mesenchymal stem cells derived extracellular vesicles can safely ameliorate the progression of chronic kidney diseases
BACKGROUND: Bio-products from stem/progenitor cells, such as extracellular vesicles, are likely a new promising approach for reprogramming resident cells in …
Article scientifique
Succinic acid production on xylose-enriched biorefinery streams by Actinobacillus succinogenes in batch fermentation
BACKGROUND: Co-production of chemicals from lignocellulosic biomass alongside fuels holds promise for improving the economic outlook of integrated biorefineries. In …
Article scientifique
A single generation of domestication heritably alters the expression of hundreds of genes
The genetic underpinnings associated with the earliest stages of plant and animal domestication have remained elusive. Because a genome-wide response …
Article scientifique
Hydrogen Sulfide—Mechanisms of Toxicity and Development of an Antidote
Hydrogen sulfide is a highly toxic gas-second only to carbon monoxide as a cause of inhalational deaths. Its mechanism of …
Article scientifique
Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium
Standardization of immunophenotyping requires careful attention to reagents, sample handling, instrument setup, and data analysis, and is essential for successful …