4595
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Biologie synthétique
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Publications
4595 publication(s) trouvée(s)
Article scientifique
Unique Clones of Vibrio cholerae O1 El Tor with Haitian Type ctxB Allele Implicated in the Recent Cholera Epidemics from Nigeria, Africa
BACKGROUND AND OBJECTIVES: The antimicrobial susceptibility patterns and genetic characteristics of Vibrio cholerae O1, which is responsible for several cholera …
Article scientifique
CpG site methylation in CRYAA promoter affect transcription factor Sp1 binding in human lens epithelial cells
BACKGROUND: Age-related cataract (ARC) is the leading cause of visual impairment worldwide, and α-crystallin (CRYAA) is the predominant structural protein …
Article scientifique
Characteristics of ciprofloxacin-resistant Enterobacteriaceae isolates recovered from wastewater of an Algerian hospital
INTRODUCTION: Hospital effluents are a source of environmental pollution by drugs, antibiotic-resistant bacteria, and resistance genes. Quinolones, particularly ciprofloxacin, are …
Article scientifique
Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases
We performed a Phenome-Wide Association Study (PheWAS) to identify interrelationships between the immune system genetic architecture and a wide array …
Article scientifique
Novel pH-Sensitive Cyclic Peptides
A series of cyclic peptides containing a number of tryptophan (W) and glutamic acid (E) residues were synthesized and evaluated …
Article scientifique
eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants
BACKGROUND: We explored premature stop-gain variants to test the hypothesis that variants, which are likely to have a consequence on …
Article scientifique
Prevalence of adhesin and toxin genes in E. coli strains isolated from diarrheic and non-diarrheic pigs from smallholder herds in northern and eastern Uganda
BACKGROUND: Enterotoxigenic E. coli (ETEC) significantly contribute to diarrhea in piglets and weaners. The smallholder pig producers in Uganda identified …
Article scientifique
Alterations of Phosphodiesterases in Adrenocortical Tumors
Alterations in the cyclic (c)AMP-dependent signaling pathway have been implicated in the majority of benign adrenocortical tumors (ACTs) causing Cushing …
Article scientifique
HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3
Chromatin remodelling is essential for cardiac development. Interestingly, the role of histone chaperones has not been investigated in this regard. …
Article scientifique
Deciphering Variability of PKD1 and PKD2 in an Italian Cohort of 643 Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary kidney disease. We analysed PKD1 and PKD2, in a …
Article scientifique
Association Mapping of Main Tomato Fruit Sugars and Organic Acids
Association mapping has been widely used to map the significant associated loci responsible for natural variation in complex traits and …
Article scientifique
The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth
Dysfunctions in ribosome biogenesis cause developmental defects and increased cancer susceptibility; however, the connection between ribosome assembly and tumorigenesis remains …
Article scientifique
Triterpenoids from Acacia ataxacantha DC: antimicrobial and antioxidant activities
BACKGROUND: Acacia ataxacantha is a medicinal specie used extensively in traditional medicine of Benin republic to treat infectious diseases. Our …
Article scientifique
Carbapenemases and extended-spectrum β-lactamases producing Enterobacteriaceae isolated from Tunisian and Libyan hospitals
INTRODUCTION: The aim of the study was to investigate the prevalence of extended-spectrum β-lactamase (ESBL) and carbapenemase production among clinical …
Article scientifique
A Look into the Cell: Honey Storage in Honey Bees, Apis mellifera
Honey bees, Apis species, obtain carbohydrates from nectar and honeydew. These resources are ripened into honey in wax cells that …
Article scientifique
Patterns of Nutrition and Dietary Supplements Use in Young Egyptian Athletes: A Community-Based Cross-Sectional Survey
The aim of this study was to investigate the pattern of basic and sport nutrition as well as perspectives of …
Article scientifique
Passive acoustic monitoring reveals group ranging and territory use: a case study of wild chimpanzees (Pan troglodytes)
BACKGROUND: Assessing the range and territories of wild mammals traditionally requires years of data collection and often involves directly following …
Article scientifique
Phylogeographic Patterns in Africa and High Resolution Delineation of Genetic Clades in the Lion (Panthera leo)
Comparative phylogeography of African savannah mammals shows a congruent pattern in which populations in West/Central Africa are distinct from populations …
Article scientifique
Polyphasic characterization of Bacillus species from anthrax outbreaks in animals from South Africa and Lesotho
INTRODUCTION: Bacillus anthracis is the causative agent of anthrax, a disease endemic in regions of Northern Cape Province and Kruger …
Article scientifique
Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression
Elevation of the proinflammatory cytokine IL-6 has been implicated in depression; however, the mechanisms remain elusive. MicroRNAs (miRNAs) are small …