4595
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Biologie synthétique
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Publications
4595 publication(s) trouvée(s)
Article scientifique
The Effects of Transdermally Delivered Oleanolic Acid on Malaria Parasites and Blood Glucose Homeostasis in P. berghei-Infected Male Sprague-Dawley Rats
The present study investigated the effects of transdermally delivered oleanolic acid (OA) monotherapy and in combination with chloroquine (CHQ) on …
Article scientifique
A fast exact sequential algorithm for the partial digest problem
BACKGROUND: Restriction site analysis involves determining the locations of restriction sites after the process of digestion by reconstructing their positions …
Article scientifique
Functional and structural characterization of a novel putative cysteine protease cell wall-modifying multi-domain enzyme selected from a microbial metagenome
Abstract A current metagenomics focus is to interpret and transform collected genomic data into biological information. By combining structural, functional …
Article scientifique
Acthaside: a new chromone derivative from Acacia ataxacantha and its biological activities
Acacia ataxacantha (Fabaceae), used in traditional medicine grows in the South-West of Bénin. Ethyl acetate extract of the barks of …
Article scientifique
Genome and Proteome Analysis of Rhodococcus erythropolis MI2: Elucidation of the 4,4´-Dithiodibutyric Acid Catabolism
Rhodococcus erythropolis MI2 has the extraordinary ability to utilize the xenobiotic 4,4´-dithiodibutyric acid (DTDB). Cleavage of DTDB by the disulfide-reductase …
Article scientifique
Pinoresinol diglucoside exhibits protective effect on dexamethasone-induced osteoporosis in rats
Purpose: To investigate the effect of pinoresinol diglucoside (PDG) on dexamethasone-induced osteoporosis in rats.Methods: Sixty Wistar rats were randomly and …
Article scientifique
A Novel Non-Cumbersome Approach Towards Biosynthesis of Pectic-Oligosaccharides by Non-Aflatoxigenic Aspergillus sp. Section Flavi Strain EGY1 DSM 101520 through Citrus Pectin Fermentation
Pectic-Oligosaccharides (POS) have a growing potential in food and feed industries. To satisfy the demand of worldwide markets from POS …
Article scientifique
Tbx5 Buffers Inherent Left/Right Asymmetry Ensuring Symmetric Forelimb Formation
The forelimbs and hindlimbs of vertebrates are bilaterally symmetric. The mechanisms that ensure symmetric limb formation are unknown but they …
Article scientifique
The role of the unusual threonine string in the conversion of prion protein
Abstract The conversion of normal prion protein (PrP) into pathogenic PrP conformers is central to prion disease, but the mechanism …
Article scientifique
The Fab Fragment of a Human Anti-Siglec-9 Monoclonal Antibody Suppresses LPS-Induced Inflammatory Responses in Human Macrophages
Sepsis is a major cause of death for hospitalized patients and is characterized by massive overreaction of immune responses to …
Article scientifique
Contribution towards a Metabolite Profile of the Detoxification of Benzoic Acid through Glycine Conjugation: An Intervention Study
Benzoic acid is widely used as a preservative in food products and is detoxified in humans through glycine conjugation. Different …
Article scientifique
Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic
HIV molecular epidemiology studies analyse viral pol gene sequences due to their availability, but whole genome sequencing allows to use …
Article scientifique
Detecting the existence of gene flow between Spanish and North African goats through a coalescent approach
Abstract Human-driven migrations are one of the main processes shaping the genetic diversity and population structure of domestic species. However, …
Article scientifique
Production of Phloroglucinol, a Platform Chemical, in Arabidopsis using a Bacterial Gene
Phloroglucinol (1,3,5-trihydroxybenzene; PG) and its derivatives are phenolic compounds that are used for various industrial applications. Current methods to synthesize …
Article scientifique
Poor Compliance to Hormone Therapy and Decreased Bone Mineral Density in Women with Premature Ovarian Insufficiency
Premature ovarian insufficiency leads to through infertility and estrogen deficiency. Optimal management encompasses estrogen replacement therapy. Long-term outcome of women …
Article scientifique
In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin
BACKGROUND: The emergence of artemisinin-resistant Plasmodium falciparum strains poses a serious challenge to the control of malaria. This necessitates the …
Article scientifique
Characterisation of Commensal Escherichia coli Isolated from Apparently Healthy Cattle and Their Attendants in Tanzania
While pathogenic types of Escherichia coli are well characterized, relatively little is known about the commensal E. coli flora. In …
Article scientifique
Potential for Nitrogen Fixation in the Fungus-Growing Termite Symbiosis
Termites host a gut microbiota of diverse and essential symbionts that enable specialization on dead plant material; an abundant, but …
Article scientifique
Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis
Treatment for human African trypanosomiasis is dependent on the species of trypanosome causing the disease and the stage of the …
Article scientifique
Cholera Rapid Test with Enrichment Step Has Diagnostic Performance Equivalent to Culture
Cholera rapid diagnostic tests (RDT) could play a central role in outbreak detection and surveillance in low-resource settings, but their …