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Publications
4595 publication(s) trouvée(s)
Article scientifique
Red Sea Atlantis II brine pool nitrilase with unique thermostability profile and heavy metal tolerance
BACKGROUND: Nitrilases, which hydrolyze nitriles in a one-step reaction into carboxylic acids and ammonia, gained increasing attention because of the …
Article scientifique
Analysis of functional germline variants in APOBEC3 and driver genes on breast cancer risk in Moroccan study population
BACKGROUND: Breast cancer (BC) is the most prevalent cancer in women and a major public health problem in Morocco. Several …
Article scientifique
A Chimeric Affinity Tag for Efficient Expression and Chromatographic Purification of Heterologous Proteins from Plants
The use of plants as expression hosts for recombinant proteins is an increasingly attractive option for the production of complex …
Article scientifique
Two Distinct Yersinia pestis Populations Causing Plague among Humans in the West Nile Region of Uganda
BACKGROUND: Plague is a life-threatening disease caused by the bacterium, Yersinia pestis. Since the 1990s, Africa has accounted for the …
Article scientifique
Production of Human papillomavirus pseudovirions in plants and their use in pseudovirion-based neutralisation assays in mammalian cells
Human papillomaviruses (HPV) cause cervical cancer and have recently also been implicated in mouth, laryngeal and anogenital cancers. There are …
Article scientifique
Adenosine A2A Receptor Blockade Prevents Rotenone-Induced Motor Impairment in a Rat Model of Parkinsonism
Pharmacological studies implicate the blockade of adenosine receptorsas an effective strategy for reducing Parkinson's disease (PD) symptoms. The objective of …
Article scientifique
Sympatric speciation in structureless environments
BACKGROUND: Darwin and the architects of the Modern Synthesis found sympatric speciation difficult to explain and suggested it is unlikely …
Article scientifique
Development of safe, effective and immunogenic vaccine candidate for diarrheagenic Escherichia coli main pathotypes in a mouse model
BACKGROUND: Enteric and diarrheal diseases are important causes of childhood death in the developing world. These diseases are responsible for …
Article scientifique
Complete mitochondrial genome of the Verticillium-wilt causing plant pathogen Verticillium nonalfalfae
Verticillium nonalfalfae is a fungal plant pathogen that causes wilt disease by colonizing the vascular tissues of host plants. The …
Article scientifique
Rg3-enriched ginseng extract ameliorates scopolamine-induced learning deficits in mice
BACKGROUND: Ginseng (Panax ginseng C.A. Meyer) has been used as a traditional herb in the treatment of many medical disorders. …
Article scientifique
The Malarial Exported PFA0660w Is an Hsp40 Co-Chaperone of PfHsp70-x
Plasmodium falciparum, the human pathogen responsible for the most dangerous malaria infection, survives and develops in mature erythrocytes through the …
Article scientifique
Synergistic anti-malarial action of cryptolepine and artemisinins
BACKGROUND: Cryptolepine (CPE) is the major indoloquinoline isolated from the popular West African anti-malarial plant, Cryptolepis sanguinolenta. CPE possesses various …
Article scientifique
Developmental Structural Tooth Defects in Dogs – Experience From Veterinary Dental Referral Practice and Review of the Literature
Developmental tooth abnormalities in dogs are uncommon in general veterinary practice but understanding thereof is important for optimal management in …
Article scientifique
Three-Dimensional Characterization of Mechanical Interactions between Endothelial Cells and Extracellular Matrix during Angiogenic Sprouting
We studied the three-dimensional cell-extracellular matrix interactions of endothelial cells that form multicellular structures called sprouts. We analyzed the data …
Article scientifique
Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines
BACKGROUND: The link between inflammation and cancer has been confirmed by the use of anti-inflammatory therapies in cancer prevention and …
Article scientifique
Epidemiology and Burden of Bloodstream Infections Caused by Extended-Spectrum Beta-Lactamase Producing Enterobacteriaceae in a Pediatric Hospital in Senegal
CONTEXT: Severe bacterial infections are not considered as a leading cause of death in young children in sub-Saharan Africa. The …
Article scientifique
Listeria monocytogenes: An emerging food-borne pathogen and its public health implications
INTRODUCTION: Listeria monocytogenes is considered one of the most important food-borne pathogens transmitted to humans via contaminated food. The aim …
Article scientifique
Antimicrobial susceptibility and molecular epidemiology of extended-spectrum beta-lactamase-producing Enterobacteriaceae from intensive care units at Hamad Medical Corporation, Qatar
BACKGROUND: The emergence of extended-spectrum beta-lactamase (ESBL)-producing isolates has important clinical and therapeutic implications. High prevalence of ESBL-producing Enterobacteriaceae has …
Article scientifique
Impact of different cell penetrating peptides on the efficacy of antisense therapeutics for targeting intracellular pathogens
There is a pressing need for novel and innovative therapeutic strategies to address infections caused by intracellular pathogens. Peptide nucleic …
Article scientifique
Lipid Droplet Formation, Their Localization and Dynamics during Leishmania major Macrophage Infection
Leishmania, the causative agent of vector-borne diseases, known as leishmaniases, is an obligate intracellular parasite within mammalian hosts. The outcome …