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4586 publication(s) trouvée(s)
Article scientifique
The Function of FK506-Binding Protein 13 in Protein Quality Control Protects Plasma Cells from Endoplasmic Reticulum Stress-Associated Apoptosis
Plasma cells (PCs) are exposed to intense endoplasmic reticulum (ER) stress imposed by enormous rates of immunoglobulin (Ig) synthesis and …
Article scientifique
Congenital malformations and medical conditions associated with orofacial clefts in children in Burkina Faso
BACKGROUND: Orofacial clefts are usually isolated cases but can be associated with other congenital malformations that are either recognised or …
Article scientifique
Experimental demonstration of the possible role of Acanthamoeba polyphaga in the infection and disease progression in Buruli Ulcer (BU) using ICR mice
The transmission of Buruli ulcer (BU), caused by Mycobacterium ulcerans (MU), remains puzzling although a number of hypothesis including through …
Article scientifique
Purification, characterization and amino acid content of cholesterol oxidase produced by Streptomyces aegyptia NEAE 102
BACKGROUND: There is an increasing demand on cholesterol oxidase for its various industrial and clinical applications. The current research was …
Article scientifique
Lentiviral vectors can be used for full-length dystrophin gene therapy
Abstract Duchenne Muscular Dystrophy (DMD) is caused by a lack of dystrophin expression in patient muscle fibres. Current DMD gene …
Article scientifique
Evidence for salicylic acid signalling and histological changes in the defence response of Eucalyptus grandis to Chrysoporthe austroafricana
Eucalyptus species are cultivated for forestry and are of economic importance. The fungal stem canker pathogen Chrysoporthe austroafricana causes disease …
Article scientifique
Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome
BACKGROUND: Chronic Fatigue Syndrome (CFS) is a prevalent debilitating condition that affects approximately 250,000 people in the UK. There is …
Article scientifique
Disturbed sensorimotor and electrophysiological patterns in lead intoxicated rats during development are restored by curcumin I
Lead poisoning is one of the most significant health problem of environmental origin. It is known to cause different damages …
Article scientifique
Human and Epstein-Barr Virus miRNA Profiling as Predictive Biomarkers for Endemic Burkitt Lymphoma
malaria co-infections. Central to BL oncogenesis is the over-expression of the MYC proto-oncogene which is caused by a translocation of …
Article scientifique
Respiratory viruses in patients with influenza-like illness in Senegal: Focus on human respiratory adenoviruses
BACKGROUND: Human adenoviruses (HAdVs) are highly contagious pathogens that are associated with a wide spectrum of human illnesses involving the …
Article scientifique
Human paraoxonase 1 overexpression in mice stimulates HDL cholesterol efflux and reverse cholesterol transport
This study was aimed to investigate the effect of human PON1 overexpression in mice on cholesterol efflux and reverse cholesterol …
Article scientifique
HLBT-100: a highly potent anti-cancer flavanone from Tillandsia recurvata (L.) L.
The incidence and mortalities from cancers remain on the rise worldwide. Despite significant efforts to discover and develop novel anticancer …
Article scientifique
Metabolomics reveals biotic and abiotic elicitor effects on the soft coral Sarcophyton ehrenbergi terpenoid content
Abstract The effects of six biotic and abiotic elicitors, i.e. MeJA (methyl jasmonate), SA (salicylic acid), ZnCl 2 , glutathione …
Article scientifique
Hypolipidemic effect and activation of Lecithin Cholesterol Acyl Transferase (LCAT) by aqueous extract of Spirulina platensis during toxicological investigation
Spirulina platensis produced in Nomayos (Cameroon) is used as a dietary supplement. S. platensis is known as a neutraceutical with …
Article scientifique
Discrete call types referring to predation risk enhance the efficiency of the meerkat sentinel system
Sentinel behaviour, a form of coordinated vigilance, occurs in a limited range of species, mostly in cooperative breeders. In some …
Article scientifique
Antibacterial and antibiotic resistance modulatory activities of leaves and bark extracts of Recinodindron heudelotii (Euphorbiaceae) against multidrug-resistant Gram-negative bacteria
BACKGROUND: Recinodindron heudelotii (Euphorbiaceae) is a plant used in Africa, particularly in Cameroon to treat various ailments including bacterial infections. …
Article scientifique
First report on bla NDM-1-producing Acinetobacter baumannii in three clinical isolates from Ethiopia
Multidrug-resistant Gram-negative bacterial infections are recognized as one of the major threats to global health. In this study, we describe …
Article scientifique
Morphological and morphometric specializations of the lung of the Andean goose, Chloephaga melanoptera: A lifelong high-altitude resident
High altitude flight in rarefied, extremely cold and hypoxic air is a very challenging activity. Only a few species of …
Article scientifique
Extracellular Hsp90 and TGFβ regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model
BACKGROUND: Tumour metastasis remains the major cause of death in cancer patients and, to date, the mechanism and signalling pathways …
Article scientifique
An assessment of the quality of the I-DSD and the I-CAH registries - international registries for rare conditions affecting sex development
BACKGROUND: With the proliferation of rare disease registries, there is a need for registries to undergo an assessment of their …