4575
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Biologie synthétique
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Publications
4575 publication(s) trouvée(s)
Article scientifique
Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors
The infectious prion protein (PrP Sc or prion) is derived from its cellular form (PrP C ) through a conformational …
Article scientifique
Curative role of lactulose, L-carnitine, alpha-lipoic acid and combination of L-carnitine and alpha-lipoic acid in a rat model of acute hepatic encephalopathy: Biochemical observations
Purpose: To determine whether a combination L-carnitine and α-lipoic acid (ALA) can alleviate the toxic effects of thioacetamide (TAA) via …
Article scientifique
An unusual complication of the traditional treatment of a closed fracture – generalized tetanus: a case report
BACKGROUND: Tetanus is a severe infectious disease that can lead to death. The clinical manifestations are due to an exotoxin …
Article scientifique
Geigerin-induced cytotoxicity in a murine myoblast cell line (C2C12)
Geigeria poisoning in sheep, locally known as 'vermeersiekte', is an economically important plant poisoning in southern Africa. The toxic principles …
Article scientifique
Virulence and extended-spectrum β-lactamase encoding genes in Escherichia coli recovered from chicken meat intended for hospitalized human consumption
AIM: genes). MATERIALS AND METHODS: ). RESULTS: genes was 3 (37.5%) and 2 (25%) isolates. CONCLUSION: in frozen chicken meat …
Article scientifique
Craniofacial manifestations in osteogenesis imperfecta type III in South Africa
OBJECTIVES: Osteogenesis imperfecta type III (OMIM 259420) is a severe autosomal recessive disorder. Affected individuals have multiple fractures, develop limb …
Article scientifique
Differential inhibition of adenylylated and deadenylylated forms of M. tuberculosis glutamine synthetase as a drug discovery platform
Glutamine synthetase is a ubiquitous central enzyme in nitrogen metabolism that is controlled by up to four regulatory mechanisms, including …
Article scientifique
New species of Auritella (Inocybaceae) from Cameroon, with a worldwide key to the known species
Two new species in the genus Auritella (Inocybaceae) are described as new from tropical rainforest in Cameroon. Descriptions, photographs, line …
Article scientifique
A highly efficient ligation-independent cloning system for CRISPR/Cas9 based genome editing in plants
Most current methods for constructing guide RNAs (gRNA) for the CRISPR/Cas9 genome editing system, depend on traditional cloning using specific …
Article scientifique
Protocol for the EMPHASIS study; epigenetic mechanisms linking maternal pre-conceptional nutrition and children’s health in India and Sub-Saharan Africa
BACKGROUND: Animal studies have shown that nutritional exposures during pregnancy can modify epigenetic marks regulating fetal development and susceptibility to …
Article scientifique
Dimensionality reduction and class prediction algorithm with application to microarray Big Data
The recent technology development in the concern of microarray experiments has provided many new potentialities in terms of simultaneous measurement. …
Article scientifique
Multi-site cholera surveillance within the African Cholera Surveillance Network shows endemicity in Mozambique, 2011–2015
BACKGROUND: Mozambique suffers recurrent annual cholera outbreaks especially during the rainy season between October to March. The African Cholera Surveillance …
Article scientifique
Asymmetric BMP4 signalling improves the realism of kidney organoids
We present a strategy for increasing the anatomical realism of organoids by applying asymmetric cues to mimic spatial information that …
Article scientifique
Identification of a key role of widespread epigenetic drift in Barrett’s esophagus and esophageal adenocarcinoma
BACKGROUND: Recent studies have identified age-related changes in DNA methylation patterns in normal and cancer tissues in a process that …
Article scientifique
Correlates of multi-drug non-susceptibility in enteric bacteria isolated from Kenyan children with acute diarrhea
BACKGROUND: Reduced antimicrobial susceptibility threatens treatment efficacy in sub-Saharan Africa, where data on the burden and correlates of antibiotic resistance …
Article scientifique
Epidemiological link of a major cholera outbreak in Greater Accra region of Ghana, 2014
BACKGROUND: Cholera remains an important public health challenge globally. Several pandemics have occurred in different parts of the world and …
Article scientifique
Extended spectrum and metalo beta-lactamase producing airborne Pseudomonas aeruginosa and Acinetobacter baumanii in restricted settings of a referral hospital: a neglected condition
Frequently encountered multidrug-resistant bacterial isolates of P. aeruginosa and A. baumannii are common and prevalent in a hospital environment. The …
Article scientifique
Whole genome population genetics analysis of Sudanese goats identifies regions harboring genes associated with major traits
Sudan is endowed with a variety of indigenous goat breeds which are used for meat and milk production and which …
Article scientifique
Phenotypic and genotypic characterization of antimicrobial susceptibility of avian pathogenic Escherichia coli isolated from broiler chickens
AIM: isolated from diseased and freshly dead broilers. MATERIALS AND METHODS: ). RESULTS: had the lowest prevalence (23%). CONCLUSION: The …
Article scientifique
Bacillus Cereus isolation and load from raw cow milk sold in Markets of Haramaya District, eastern Ethiopia
Bacillus cereus is a spore-forming bacterium that is widely distributed in the environment and can be detected in a variety …