4419
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24442
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Biologie synthétique
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Publications
4419 publication(s) trouvée(s)
Article scientifique
COL5A1 gene variants previously associated with reduced soft tissue injury risk are associated with elite athlete status in rugby
BACKGROUND: Two common single nucleotide polymorphisms within the COL5A1 gene (SNPs; rs12722 C/T and rs3196378 C/A) have previously been associated …
Article scientifique
Somatic embryogenesis from seeds in a broad range of Vitis vinifera L. varieties: rescue of true-to-type virus-free plants
BACKGROUND: Somatic embryogenesis is the preferred method for cell to plant regeneration in Vitis vinifera L. However, low frequencies of …
Article scientifique
Alkaline peptone water enrichment with a dipstick test to quickly detect and monitor cholera outbreaks
BACKGROUND: Detection, confirmation and monitoring of cholera outbreaks in many developing countries including Uganda is a big challenge due to …
Article scientifique
Immunohistochemistry defined subtypes of breast cancer in 678 Sudanese and Eritrean women; hospitals based case series
BACKGROUND: Breast cancer is the most common malignancy accounting for 25% of all cancers in females. In Africa, breast cancer …
Article scientifique
Characterization of hormonal receptors and human epidermal growth factor receptor-2 in tissues of women with breast cancer at Muhimbili National Hospital, Dar es salaam, Tanzania
Breast cancer is a leading cause of morbidity and deaths among women worldwide. In Tanzania there is no published data …
Article scientifique
Multi-region and single-cell sequencing reveal variable genomic heterogeneity in rectal cancer
BACKGROUND: Colorectal cancer is a heterogeneous group of malignancies with complex molecular subtypes. While colon cancer has been widely investigated, …
Article scientifique
CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion
BACKGROUND: We have previously validated three novel CD44-downstream positively regulated transcriptional targets, including Cortactin, Survivin and TGF-β2, and further characterized …
Article scientifique
Performance verification of the new fully automated Aquios flow cytometer PanLeucogate (PLG) platform for CD4-T-lymphocyte enumeration in South Africa
BACKGROUND: The National Health Laboratory Service (NHLS) offers wide-scale CD4 testing through a network of laboratories in South Africa. A …
Article scientifique
Antiquorum sensing, antibiofilm formation and cytotoxicity activity of commonly used medicinal plants by inhabitants of Borabu sub-county, Nyamira County, Kenya
Productions of various bacterial traits like production of virulence factors (e.g. toxins, enzymes), biofilm formation, luminescence among others, have been …
Article scientifique
Clinicopathologic and prognostic features of breast cancer in young women: a series from North of Morocco
BACKGROUND: Literature data reported a higher frequency of breast cancer in young women (BCYW) in developing countries. BCYW is associated …
Article scientifique
Optimization of physical conditions for the production of thermostable T1 lipase in Pichia guilliermondii strain SO using response surface methodology
Pichia guilliermondii was found capable of expressing the recombinant thermostable lipase without methanol under the control of methanol dependent alcohol …
Article scientifique
The Asian house shrew Suncus murinus as a reservoir and source of human outbreaks of plague in Madagascar
Identifying key reservoirs for zoonoses is crucial for understanding variation in incidence. Plague re-emerged in Mahajanga, Madagascar in the 1990s …
Article scientifique
Conservation of Nonsense-Mediated mRNA Decay Complex Components Throughout Eukaryotic Evolution
Nonsense-mediated mRNA decay (NMD) is an essential eukaryotic process regulating transcript quality and abundance, and is involved in diverse processes …
Article scientifique
drLumi: An open-source package to manage data, calibrate, and conduct quality control of multiplex bead-based immunoassays data analysis
Multiplex bead-based immunoassays are used to measure concentrations of several analytes simultaneously. These assays include control standard curves (SC) to …
Article scientifique
Farmers’ perception of termites in agriculture production and their indigenous utilization in Northwest Benin
BACKGROUND: Although termites are considered as agricultural pests, they play an important role in maintaining the ecosystem. Therefore, it matters …
Article scientifique
Identification of host DEAD-box RNA helicases that regulate cellular tropism of oncolytic Myxoma virus in human cancer cells
Myxoma virus (MYXV), a Leporipoxvirus, is being developed as an oncolytic virotherapeutic for the treatment of a variety of human …
Article scientifique
Whole Y-chromosome sequences reveal an extremely recent origin of the most common North African paternal lineage E-M183 (M81)
E-M183 (E-M81) is the most frequent paternal lineage in North Africa and thus it must be considered to explore past …
Article scientifique
Association of rs6983267 at 8q24, HULC rs7763881 polymorphisms and serum lncRNAs CCAT2 and HULC with colorectal cancer in Egyptian patients
The impact of HULC rs7763881 on colorectal cancer (CRC) susceptibility is not yet known. Also, the biological function of the …
Article scientifique
Species composition and environmental adaptation of indigenous Chinese cattle
Indigenous Chinese cattle combine taurine and indicine origins and occupy a broad range of different environments. By 50 K SNP …
Article scientifique
Effect of Trait Heritability, Training Population Size and Marker Density on Genomic Prediction Accuracy Estimation in 22 bi-parental Tropical Maize Populations
Genomic selection is being used increasingly in plant breeding to accelerate genetic gain per unit time, one of the most …