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Biologie synthétique
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Publications
4336 publication(s) trouvée(s)
Article scientifique
Draft genome sequence of Paenibacillus sp. EZ-K15 isolated from wastewater systems
OBJECTIVES: Paenibacillus species, belonging to the family Paenibacillaceae, are able to survive for long periods under adverse environmental conditions. Several …
Article scientifique
Beneficial mutation-selection dynamics in finite asexual populations: a free boundary approach
Using a free boundary approach based on an analogy with ice melting models, we propose a deterministic PDE framework to …
Article scientifique
Joubert’s syndrome and related disorders and home-based peritoneal dialysis in East Africa: a case report
BACKGROUND: Joubert's syndrome is a rare condition affecting an estimated 1:80,000-1:100,000 individuals. There is underdevelopment of the cerebellar vermis resulting …
Article scientifique
Domesticating Cancer: An Evolutionary Strategy in the War on Cancer
Since cancer shares the same molecular machinery as the host, most therapeutic interventions which aim to target cancer would inadvertently …
Article scientifique
Structural changes of the macula and optic nerve head in the remaining eyes after enucleation for retinoblastoma: an optical coherence tomography study
BACKGROUND: To describe objectively the possible structural changes of the macula and optic nerve head in the free eyes of …
Article scientifique
First Report of Lasiodiplodia theobromae Causing Needle Blight and Stem Canker Diseases on Araucaria heterophylla in Ethiopia
Abstract Canker and needle blight of Araucaria heterophylla (Norfolk Island pine) trees were observed during the surveys conducted in Addis …
Article scientifique
Highlights of the second ISCB Student Council Symposium in Africa, 2017
Student Council Symposiums (SCSs) have been found to be very useful for students and young researchers. This is especially true …
Article scientifique
Genetic investigation of XPA gene: high frequency of the c.682C>T mutation in Moroccan XP patients with moderate clinical profile
OBJECTIVE: Xeroderma pigmentosum (XP) is a genetically and clinically heterogeneous disease, associated with an inherited defect in one of eight …
Article scientifique
Low cost, low tech SNP genotyping tools for resource-limited areas: Plague in Madagascar as a model
BACKGROUND: Genetic analysis of pathogenic organisms is a useful tool for linking human cases together and/or to potential environmental sources. …
Article scientifique
Bacteriological study of calf colisepticemia in Alage Dairy Farm, Southern Ethiopia
OBJECTIVE: This study was designed to estimate the prevalence of E. coli which is the main cause of colisepticemia and …
Article scientifique
Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats
BACKGROUND: This study aims at characterizing the in vitro metabolism of cryptolepine using human and rat hepatocytes, identifying metabolites in …
Article scientifique
Divergent susceptibilities to AAV-SaCas9-gRNA vector-mediated genome-editing in a single-cell-derived cell population
OBJECTIVE: Recombinant adeno-associated virus (AAV)-based vectors are characterized by their robust and safe transgene delivery. The CRISPR/Cas9 and guide RNA …
Article scientifique
Economic evaluation of 2014 cholera outbreak in Ghana: a household cost analysis
INTRODUCTION: Ghana experienced its worst cholera outbreak in three decades in 2014. Evidence of cholera economic costs on affected households …
Article scientifique
Genetic variation in N- and C-terminal regions of bovine DNAJA1 heat shock protein gene in African, Asian and American cattle
DNAJA1 or heat shock protein 40 (Hsp40) is associated with heat adaptation in various organisms. We amplified and sequenced a …
Article scientifique
Interaction between environment, nutrient-derived metabolites and immunity: A possible role in malaria susceptibility/resistance in Fulani and Dogon of Mali
The role of some nutrient-derived metabolites on the innate and adaptive immune responses is now established. Global research approach investigating …
Article scientifique
Circulating microRNA’s as a diagnostic tool for hepatocellular carcinoma in a hyper endemic HIV setting, KwaZulu-Natal, South Africa: a case control study protocol focusing on viral etiology
BACKGROUND: A wide range of studies has investigated the diagnostic proficiency of extracellular microRNAs (miRNAs) in hepatocellular cancer (HCC). HCC …
Article scientifique
Evolution of cytokinesis-related protein localization during the emergence of multicellularity in volvocine green algae
BACKGROUND: The volvocine lineage, containing unicellular Chlamydomonas reinhardtii and differentiated multicellular Volvox carteri, is a powerful model for comparative studies …
Article scientifique
Bivariate longitudinal data analysis: a case of hypertensive patients at Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia
OBJECTIVE: Longitudinal data are often collected to study the evolution of biomedical markers. The study of the joint evolution of …
Article scientifique
Effects of interactions between common genetic variants and smoking on colorectal cancer
Although genome-wide association studies (GWAS) have identified variants in approximately 40 susceptibility loci for colorectal cancer (CRC), there are few …
Article scientifique
Using standard keywords in publications to facilitate updates of new fungal taxonomic names
Abstract The combination of manual curation and the reliance on updates from submitters to the public sequence databases is currently …