4149
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Publications
4149 publication(s) trouvée(s)
Article scientifique
GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation
The renin-angiotensin system regulates blood pressure and fluid balance in the body primarily via angiotensin receptor 1 (AT1R). Renal AT1R …
Article scientifique
Re-highlighting the action of PPARγ in treating metabolic diseases
Peroxisome proliferator-activated receptor γ (PPARγ) is a member of the nuclear receptor family and plays an important role in adipocyte …
Article scientifique
Genetic characterization of extraintestinal Escherichia coli isolates from chicken, cow and swine
Phenotypic determination of antimicrobial resistance in bacteria is very important for diagnosis and treatment, but sometimes this procedure needs further …
Article scientifique
Haemolysis and haem oxygenase-1 induction during persistent “asymptomatic” malaria infection in Burkinabé children
BACKGROUND: The haemolysis associated with clinical episodes of malaria results in the liberation of haem, which activates the enzyme haem …
Article scientifique
Targeting HOX-PBX interactions causes death in oral potentially malignant and squamous carcinoma cells but not normal oral keratinocytes
BACKGROUND: High HOX gene expression has been described in many cancers, including oral squamous cell carcinoma and the functional roles …
Article scientifique
Complete genome sequence of Enterococcus durans KLDS6.0933, a potential probiotic strain with high cholesterol removal ability
Enterococci are commensal bacteria in the mammalian gastrointestinal tract which play an important role in the production of various fermented …
Article scientifique
Rapid in vitro detection of CTX-M groups 1, 2, 8, 9 resistance genes by LAMP assays
BACKGROUND: The prevalence of bacteria producing CTX-M Extended-Spectrum β-lactamases (ESBLs) has increased around the world and some of them became …
Article scientifique
QTL Mapping Combined With Comparative Analyses Identified Candidate Genes for Reduced Shattering in Setaria italica
Setaria (L.) P. Beauv is a genus of grasses that belongs to the Poaceae (grass) family, subfamily Panicoideae. Two members …
Article scientifique
Genetic variants in SEC16B are associated with body composition in black South Africans
OBJECTIVE: The latest genome-wide association studies of obesity-related traits have identified several genetic loci contributing to body composition (BC). These …
Article scientifique
Public health risks of Escherichia coli and Staphylococcus aureus in raw bovine milk sold in informal markets in Egypt
INTRODUCTION: Milk is an important food in Egypt and most of it is sold as raw milk in informal markets. …
Article scientifique
Coinfections identified from metagenomic analysis of cervical lymph nodes from tularemia patients
BACKGROUND: Underlying coinfections may complicate infectious disease states but commonly go unnoticed because an a priori clinical suspicion is usually …
Article scientifique
Influence of some environmental conditions on stability and activity of Bacillus thuringiensis formulations against the cotton leaf worm, Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae)
The entomopathogenic bacterium Bacillus thuringiensis ( Bt ) has been used in crop protection for the last 70 years; however, …
Article scientifique
High level of drug resistance by gram-negative bacteria from selected sewage polluted urban rivers in Addis Ababa, Ethiopia
OBJECTIVE: The aim of this study was to determine the level of drug resistance by gram-negative bacteria isolated from selected …
Article scientifique
Novel Trajectories of Bromocriptine Antidiabetic Action: Leptin-IL-6/ JAK2/p-STAT3/SOCS3, p-IR/p-AKT/GLUT4, PPAR-γ/Adiponectin, Nrf2/PARP-1, and GLP-1
Bromocriptine (BC), a sympatholytic dopaminergic D2 receptor agonist, has been comprehensively used in clinic to treat Parkinson's disease (PD) and …
Article scientifique
Strengthening regulatory capacity for gene drives in Africa: leveraging NEPAD’s experience in establishing regulatory systems for medicines and GM crops in Africa
, which advocated for a coevolutionary approach where technology development goes hand in hand with regulation. Furthermore, most AU member …
Article scientifique
STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer
BACKGROUND: Serine/threonine protein kinase 25 (STK25) is critical in regulating whole-body glucose and insulin homeostasis and the accumulation of ectopic …
Article scientifique
Prevalence and antibiotic susceptibility patterns of Shigella and Salmonella among children aged below five years with Diarrhoea attending Nigist Eleni Mohammed memorial hospital, South Ethiopia
BACKGROUND: Diarrhoeal disease is the second leading cause of death among children aged below 5 years. Even though, both preventable …
Article scientifique
Enhanced physicochemical stability and efficacy of angiotensin I-converting enzyme (ACE) - inhibitory biopeptides by chitosan nanoparticles optimized using Box-Behnken design
Bromelain-generated biopeptides from stone fish protein exhibit strong inhibitory effect against ACE and can potentially serve as designer food (DF) …
Article scientifique
Multidrug resistance among Escherichia coli and Klebsiella pneumoniae carried in the gut of out-patients from pastoralist communities of Kasese district, Uganda
BACKGROUND: Antimicrobial resistance is a worldwide public health emergency that requires urgent attention. Most of the effort to prevent this …
Article scientifique
Biological control of Podosphaera xanthii the causal agent of squash powdery mildew disease by upregulation of defense-related enzymes
Squash ( Cucurbita pepo L.), one of the most important vegetable crops for human nutrition all over the world, is …