4149
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Biologie synthétique
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Publications
4149 publication(s) trouvée(s)
Article scientifique
Widespread antimicrobial resistance among bacterial infections in a Rwandan referral hospital
BACKGROUND: Resistance among bacterial infections is increasingly well-documented in high-income countries; however, relatively little is known about bacterial antimicrobial resistance …
Article scientifique
Behavioural compass: animal behaviour recognition using magnetometers
Animal-borne data loggers today often house several sensors recording simultaneously at high frequency. This offers opportunities to gain fine-scale insights …
Article scientifique
An omics-based strategy using coenzyme Q10 in patients with Parkinson’s disease: concept evaluation in a double-blind randomized placebo-controlled parallel group trial
BACKGROUND: This study focuses on genetically stratified subgroups of Parkinson's disease patients (PD) with an enrichment of risk variants in …
Article scientifique
High snakebite underreporting rate in the Centre Region of Cameroon: an observational study
BACKGROUND: In Cameroon, since the first epidemiological week held in 2015, snakebites have been registered among Potential Epidemic Diseases (PED). …
Article scientifique
ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells
BACKGROUND: HER3/ErbB3 receptor deletion or blockade leads to tumor cell apoptosis, whereas its overexpression confers anti-cancer drug resistance through upregulation …
Article scientifique
RNA sequencing analysis of Cymbidium goeringii identifies floral scent biosynthesis related genes
BACKGROUND: Cymbidium goeringii belongs to the Orchidaceae, which is one of the most abundant angiosperm families. Cymbidium goeringii consist with …
Article scientifique
Sphere-forming culture enriches liver cancer stem cells and reveals Stearoyl-CoA desaturase 1 as a potential therapeutic target
BACKGROUNDS: The role of sphere-forming culture in enriching subpopulations with stem-cell properties in hepatocellular carcinoma (HCC) is unclear. The present …
Article scientifique
Constraints to counting bioluminescence producing cells by a commonly used transgene promoter and its implications for experimental design
It is routine to genetically modify cells to express fluorescent or bioluminescent reporter proteins to enable tracking or quantification of …
Article scientifique
Methylation of Glutathione-S-Transferase P1 Promotor in Egyptian Females with Breast Cancer
Background: Breast cancer (BC) is the second most common cancer after the lung cancer worldwide and number one killing cancer …
Article scientifique
Ainhum, a rare mutilating dermatological disease in a female Cameroonian: a case report
BACKGROUND: Ainhum is an idiopathic dermatological disease characterized by a progressive constricting ring usually on the fifth toe, which may …
Article scientifique
Diagnosis of Fraser syndrome missed out until the age of six months old in a low-resource setting: a case report
BACKGROUND: Fraser syndrome is a rare genetic disorder that often presents with ocular, renal, genital and limb's congenital anomalies. The …
Article scientifique
Delayed second dose of oral cholera vaccine administered before high-risk period for cholera transmission: Cholera control strategy in Lusaka, 2016
BACKGROUND: In April 2016, an emergency vaccination campaign using one dose of Oral Cholera Vaccine (OCV) was organized in response …
Article scientifique
Diagnostic Performance of microRNA-122 and microRNA-224 in Hepatitis C Virus-Induced Hepatocellular Carcinoma (HCC)
Background and objectives: Hepatocellular carcinoma (HCC) is a potential health problem in Egypt because of the high prevalence of HCV …
Article scientifique
The role of gamma irradiation and storage at 28 ± 2 °C on the inactivation of Listeria monocytogenes, Escherichia coli and Salmonella enterica serotype Typhimurium in sun-dried Legon-18 pepper (Capsicum annuum) powder
Low moisture foods like spices are known to be contaminated with pathogens, sun-dried chili pepper powder not left out. A …
Article scientifique
Genotyping by Sequencing for Plant Breeding- A Review
Breeding of crops can be accomplished through two major approaches i.e., conventional and molecular.Variety development through the former approach requires …
Article scientifique
The accuracy of extended-spectrum beta-lactamase detection in Escherichia coli and Klebsiella pneumoniae in South African laboratories using the Vitek 2 Gram-negative susceptibility card AST-N255
Background: Phenotypic detection of extended-spectrum beta-lactamases (ESBLs) is based on the inhibition of ESBL enzymes by β-lactamase inhibitors and on …
Article scientifique
Combined Hyperthermia and Radiation Therapy for Treatment of Hepatocellular Carcinoma
Background: There is no doubt that hyperthermia is one of the powerful radiosensitizers. Finding a proper mechanism working in hyperthermia/radiation …
Article scientifique
Field assessment of insecticide dusting and bait station treatment impact against rodent flea and house flea species in the Madagascar plague context
Bubonic is the most prevalent plague form in Madagascar. Indoor ground application of insecticide dust is the conventional method used …
Article scientifique
The NEDD8-activating enzyme inhibitor MLN4924 sensitizes a TNFR1+ subgroup of multiple myeloma cells for TNF-induced cell death
Abstract The NEDD8-activating enzyme (NAE) inhibitor MLN4924 inhibits cullin-RING ubiquitin ligase complexes including the SKP1-cullin-F-box E3 ligase βTrCP. MLN4924 therefore …
Article scientifique
Antimicrobial resistance of Escherichia coli isolates from cattle in Eastern Algeria
Background and Aim: Lack of information about the antibiotic resistance in commensal Escherichia coli from Algerian livestock prompted us to …