4149
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Biologie synthétique
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Publications
4149 publication(s) trouvée(s)
Article scientifique
URM1-Mediated Ubiquitin-Like Modification Is Required for Oxidative Stress Adaptation During Infection of the Rice Blast Fungus
Ubiquitin is a small modifier protein which is usually conjugated to substrate proteins for degradation. Recent years, a number of …
Article scientifique
Management and cost of snakebite injuries at a teaching and referral hospital in Western Kenya
Background: Data on the cost of snakebite injuries may inform key pillars of universal health coverage including proper planning, allocation, …
Article scientifique
Chromosomal instability of circulating tumor DNA reflect therapeutic responses in advanced gastric cancer
Gastric cancer is characterized by chromosomal instability. In this study, we investigated chromosomal instability quantified by copy number instability (CNI) …
Article scientifique
A ten-year review of ESBL and non-ESBL Escherichia coli bloodstream infections among children at a tertiary referral hospital in South Africa
INTRODUCTION: There are few studies describing Escherichia coli (E. coli) bloodstream infection (BSI) among children in Africa, yet E.coli is …
Article scientifique
Α de novo 3.8-Mb inversion affecting the EDA and XIST genes in a heterozygous female calf with generalized hypohidrotic ectodermal dysplasia
BACKGROUND: In mammals, hypohidrotic ectodermal dysplasia (HED) is a genetic disorder that is characterized by sparse hair, tooth abnormalities, and …
Article scientifique
S100A4 released from highly bone-metastatic breast cancer cells plays a critical role in osteolysis
Bone destruction induced by breast cancer metastasis causes severe complications, including death, in breast cancer patients. Communication between cancer cells …
Article scientifique
Renoprotective effects of a novel cMet agonistic antibody on kidney fibrosis
Hepatocyte growth factor (HGF) and its receptor, cMet, activate biological pathways necessary for repair and regeneration following kidney injury. Because …
Article scientifique
Phylogeography of the dugong (Dugong dugon) based on historical samples identifies vulnerable Indian Ocean populations
We investigated the phylogeography of the dugong (Dugong dugon) across its original range using museum material from 14 natural history …
Article scientifique
Role of protein conformation and weak interactions on γ-gliadin liquid-liquid phase separation
Wheat storage proteins, gliadins, were found to form in vitro condensates in 55% ethanol/water mixture by decreasing temperature. The possible …
Article scientifique
DNA barcoding of southern African crustaceans reveals a mix of invasive species and potential cryptic diversity
Globally, crustaceans represent one of the most taxonomically diverse and economically important invertebrate group. Notwithstanding, the diversity within this group …
Article scientifique
Circulating miR-34a and miR-125b as Promising non Invasive Biomarkers in Egyptian Locally Advanced Breast Cancer Patients
Background: Breast cancer (BC) is the second most common cancer worldwide. MicroRNAs are a group of non-coding, single stranded RNAs …
Article scientifique
Synergistic action of SPI-1 gene expression in Salmonella enterica serovar typhimurium through transcriptional crosstalk with the flagellar system
BACKGROUND: Salmonella enterica serovar Typhimurium is a common food-borne pathogen. S. enterica uses a type III secretion system encoded within …
Article scientifique
The First Isolation and Molecular Characterization of Shiga Toxin-Producing Virulent Multi-Drug Resistant Atypical Enteropathogenic Escherichia coli O177 Serogroup From South African Cattle
Atypical enteropathogenic E. coli (aEPEC) is a group of diarrhoeagenic Escherichia coli with high diversity of serotypes, which lack the …
Article scientifique
Graviola (Annona muricata) attenuates behavioural alterations and testicular oxidative stress induced by streptozotocin in diabetic rats
Oxidative stresses intensify the progression of diabetes-related behavioural changes and testicular injuries. Graviola (Annona muricata), a small tree of the …
Article scientifique
Genetic relatedness in carbapenem-resistant isolates from clinical specimens in Ghana using ERIC-PCR technique
AIM: Enterobacterial repetitive intergenic consensus (ERIC) sequence analysis is a powerful tool for epidemiological analysis of bacterial species. This study …
Article scientifique
Evaluation of antimicrobial activity of chondrillasterol isolated from Vernonia adoensis (Asteraceae)
BACKGROUND: Bacteria have developed resistance to most of the current antibiotics. There is evidence suggesting that plant-derived compounds have a …
Article scientifique
Biological Activity Evaluation of Some New Benzenesulphonamide Derivatives
Bacterial resistance to antibiotics over the past few decades has become one of the most challenging problems of infectious treatment. …
Article scientifique
LPS induces inflammatory chemokines via TLR-4 signalling and enhances the Warburg Effect in THP-1 cells
The Warburg Effect has emerged as a potential drug target because, in some cancer cell lines, it is sufficient to …
Article scientifique
Impacts of environmental complexity on respiratory and gut microbiome community structure and diversity in growing pigs
The limited understanding of the interaction between rearing environment of the growing pig and the pig's microbial community impedes efforts …
Article scientifique
Escherichia coli O157:H7: distribution, molecular characterization, antimicrobial resistance patterns and source of contamination of sheep and goat carcasses at an export abattoir, Mojdo, Ethiopia
BACKGROUND: Cattle have been identified as a major reservoir of E. coli O157:H7 for human infection; the ecology of the …