4149
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23337
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Biologie synthétique
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Publications
4149 publication(s) trouvée(s)
Article scientifique
PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells
BACKGROUND: Spermatogonial stem cells (SSCs) are the cornerstone of sperm production and thus perpetual male fertility. In clinics, transplantation of …
Article scientifique
Characterization of Holstein and Normande whole milk miRNomes highlights breed specificities
The concept of milk as a healthy food has opened the way for studies on milk components, from nutrients to …
Article scientifique
Phylogeography, genetic diversity, and population structure of Nile crocodile populations at the fringes of the southern African distribution
Nile crocodiles are apex predators widely distributed in sub-Saharan Africa that have been viewed and managed as a single species. …
Article scientifique
Glycated albumin as a diagnostic tool in diabetes: An alternative or an additional test?
INTRODUCTION: Studies have revealed that glycated albumin (GA) is a useful alternative to HbA1c under conditions wherein the latter does …
Article scientifique
Controlling invasive Argentine ants, Linepithema humile, in conservation areas using horizontal insecticide transfer
Invasive ants are major agricultural and urban pests and a significant concern in conservation areas. Despite long history of control …
Article scientifique
New Perspectives on Plant Adenylyl Cyclases
It is increasingly clear that plant genomes encode numerous complex multi-domain proteins that harbour functional adenylyl cyclase (AC) centres. These …
Article scientifique
Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion
Prion or PrPSc is the proteinaceous infectious agent causing prion diseases in various mammalian species. Despite decades of research, the …
Article scientifique
Chaperone biomarkers of lifespan and penetrance track the dosages of many other proteins
Many traits vary among isogenic individuals in homogeneous environments. In microbes, plants and animals, variation in the protein chaperone system …
Article scientifique
Optimizing sgRNA length to improve target specificity and efficiency for the GGTA1 gene using the CRISPR/Cas9 gene editing system
The CRISPR/Cas9 gene editing system has enhanced the development of genetically engineered animals for use in xenotransplantation. Potential limitations to …
Article scientifique
Genomic insights into Vibrio cholerae O1 responsible for cholera epidemics in Tanzania between 1993 and 2017
BACKGROUND: Tanzania is one of seven countries with the highest disease burden caused by cholera in Africa. We studied the …
Article scientifique
Cultivated Olive Diversification at Local and Regional Scales: Evidence From the Genetic Characterization of French Genetic Resources
Molecular characterization of crop genetic resources is a powerful approach to elucidate the origin of varieties and facilitate local cultivar …
Article scientifique
Improvement and use of CRISPR/Cas9 to engineer a sperm-marking strain for the invasive fruit pest Drosophila suzukii
BACKGROUND: The invasive fruit pest Drosophila suzukii was reported for the first time in Europe and the USA in 2008 …
Article scientifique
Molecular detection and antibiotic resistance pattern of extended-spectrum beta-lactamase producing Escherichia coli in a Tertiary Hospital in Enugu, Nigeria
Abstract Background The use of antibiotic agents in the treatment of infectious diseases has greatly contributed to the decrease in …
Article scientifique
Butyrate attenuated fat gain through gut microbiota modulation in db/db mice following dapagliflozin treatment
We investigated the effect of a combination treatment with dapagliflozin (Dapa), a sodium-glucose cotransporter-2 inhibitor and butyrate on weight change …
Article scientifique
The African Genomic Medicine Training Initiative (AGMT): Showcasing a Community and Framework Driven Genomic Medicine Training for Nurses in Africa
The potential of genomic medicine in improving the quality of healthcare both at population and individual-level is well-recognized globally. However, …
Article scientifique
FOXO3 Transcription Factor Regulates IL-10 Expression in Mycobacteria-Infected Macrophages, Tuning Their Polarization and the Subsequent Adaptive Immune Response
Alveolar Macrophages play a key role in the development of a robust adaptive immune response against the agent of Tuberculosis …
Article scientifique
Population Structure and Genetic Diversity of Nile Tilapia (Oreochromis niloticus) Strains Cultured in Tanzania
Understanding population structure and genetic diversity within and between local Nile tilapia lines cultured in Tanzania is important for sustainable …
Article scientifique
Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance
Genetic research of elite athletic performance has been hindered by the complex phenotype and the relatively small effect size of …
Article scientifique
Are We Ill Because We Age?
Growing elderly populations, sometimes referred to as gray (or silver) tsunami, are an increasingly serious health and socioeconomic concern for …
Article scientifique
Rapid resistance to pesticide control is predicted to evolve in an invasive fish
Xenobiotic resistance is commonly found in species with short generation times such as bacteria, annual plants, and insects. Nevertheless, the …