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2549 publication(s) trouvée(s)
Article scientifique
Comparative Evaluation of CHROMagar COL-APSE, MicroScan Walkaway, ComASP Colistin, and Colistin MAC Test in Detecting Colistin-resistant Gram-Negative Bacteria
Colistin has become a critical antibiotic for fatal Gram-negative infections owing to the proliferation of multidrug-resistant carbapenemase-producing bacteria. Thus, cheaper, …
Article scientifique
Whole genome sequencing of extended-spectrum β-lactamase genes in Enterobacteriaceae isolates from Nigeria
Extended Spectrum β-lactamase (ESBL)-producing Enterobacteriaceae are of major concern as they are implicated in multidrug resistant nosocomial infections. They are …
Article scientifique
Vermamoeba vermiformis CDC-19 draft genome sequence reveals considerable gene trafficking including with candidate phyla radiation and giant viruses
Vermamoeba vermiformis is a predominant free-living amoeba in human environments and amongst the most common amoebae that can cause severe …
Article scientifique
Plant-based production of highly potent anti-HIV antibodies with engineered posttranslational modifications
Broadly neutralising antibodies (bNAbs) against human immunodeficiency virus type 1 (HIV-1), such as CAP256-VRC26 are being developed for HIV prevention …
Article scientifique
Occurrence, Phenotypic and Molecular Characterization of Extended-Spectrum- and AmpC- β-Lactamase Producing Enterobacteriaceae Isolated From Selected Commercial Spinach Supply Chains in South Africa
The increasing occurrence of multidrug-resistant extended-spectrum β-lactamase- (ESBL) and/or AmpC β-lactamase-producing Enterobacteriaceae in health care systems, the environment and fresh …
Article scientifique
What are the drivers of recurrent cholera transmission in Nigeria? Evidence from a scoping review
BACKGROUND: The 2018 cholera outbreak in Nigeria affected over half of the states in the country, and was characterised by …
Article scientifique
Putting RFMix and ADMIXTURE to the test in a complex admixed population
BACKGROUND: Global and local ancestry inference in admixed human populations can be performed using computational tools implementing distinct algorithms. The …
Article scientifique
Repurposing anti-diabetic drug “Sitagliptin” as a novel virulence attenuating agent in Serratia marcescens
BACKGROUND: Serratia marcescens is an emerging pathogen that causes a variety of health care associated infections. S. marcescens is equipped …
Article scientifique
PathME: pathway based multi-modal sparse autoencoders for clustering of patient-level multi-omics data
BACKGROUND: Recent years have witnessed an increasing interest in multi-omics data, because these data allow for better understanding complex diseases …
Article scientifique
Genetic Dissection of Nitrogen Use Efficiency in Tropical Maize Through Genome-Wide Association and Genomic Prediction
In sub-Saharan Africa, one of the major challenges to smallholder farmers is soils with low fertility and inability to apply …
Article scientifique
Toxicomicrobiomics: The Human Microbiome vs. Pharmaceutical, Dietary, and Environmental Xenobiotics
The harmful impact of xenobiotics on the environment and human health is being more widely recognized; yet, inter- and intraindividual …
Article scientifique
Peer Review Report For: vhcub: Virus-host codon usage co-adaptation analysis [version 1; peer review: 2 approved]
Viruses show noticeable evolution to adapt and reproduce within their hosts. Theoretically, patterns and factors that affect the codon usage …
Article scientifique
High Sensitivity C-reactive Protein Concentrations, Lipid Status And Duration Of Type-1 Diabetes
Abstract Background: Low-grade inflammation, duration of diabetes, hyperglycemia, and dyslipidemia in the presence of other traditional risk factors have been …
Article scientifique
Analysis of the role of TpUB05 antigen from Theileria parva in immune responses to malaria in humans compared to its homologue in Plasmodium falciparum; UB05 antigen
Article scientifique
Putting RFMix and ADMIXTURE to the test in a complex admixed population
Article scientifique
Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activation.
Article scientifique
Characterization of Gut Microbiota Associated with Clinical Parameters in Intrahepatic Cholestasis of Pregnant Patients
Abstract Background: Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder that specifically occurs in pregnancy. Elevated levels of liver …
Article scientifique
Molecular Characteristics and Antimicrobial Susceptibility Profile of Pseudomonas aeruginosa isolated from patients attending Healthcare Facilities in Mthatha, South Africa
Abstract Background: Pseudomonas aeruginosa is a common pathogen causing healthcare-associated infections most especially in critically ill and immunocompromised patients. This …
Article scientifique
Determinants of dehydration status and associated risk factors of cholera outbreak in Oromia, Ethiopia
Abstract Introductions: Cholera is a diarrheal disease caused by infection of the intestine with the gram-negative bacteria Vibrio cholera. According …
Article scientifique
Longitudinal assessment of antibiotic resistance gene profiles in gut microbiomes of infants at risk of eczema
Abstract Background While there is increasing knowledge about the gut microbiome, the factors influencing and the significance of the gut …