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Publications
4154 publication(s) trouvée(s)
Article scientifique
Identification of a novel pathogenic variant in PALB2 and BARD1 genes by a multigene sequencing panel in triple negative breast cancer in Morocco
Pathogenic variants (PVs) in BRCA genes have been mainly associated with an increasing risk of triple negative breast cancer (TNBC). …
Article scientifique
Benign ethnic neutropenia in a South African population, and its association with HIV acquisition and adverse event reporting in an HIV vaccine clinical trial
Benign ethnic neutropenia (BEN) is defined as a neutrophil count of <1.5×109 cells/L in healthy individuals and is more common …
Article scientifique
Anti-c-myc cholesterol based lipoplexes as onco-nanotherapeutic agents in vitro
Background: Strategies aimed at inhibiting the expression of the c-myc oncogene could provide the basis for alternative cancer treatment. In …
Article scientifique
In silico analysis of promoter regions and regulatory elements (motifs and CpG islands) of the genes encoding for alcohol production in Saccharomyces cerevisiaea S288C and Schizosaccharomyces pombe 972h-
BACKGROUND: The crucial factor in the production of bio-fuels is the choice of potent microorganisms used in fermentation processes. Despite …
Article scientifique
Advanced molecular characterization of enteropathogenic Escherichia coli isolated from diarrheic camel neonates in Egypt
Background and Aim: Camels are important livestock in Egypt on cultural and economic bases, but studies of etiological agents of …
Article scientifique
Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria
Gene drive research is progressing towards future field evaluation of modified mosquitoes for malaria control in sub-Saharan Africa. While many …
Article scientifique
Germline copy number variations in BRCA1/2 negative families: Role in the molecular etiology of hereditary breast cancer in Tunisia
Hereditary breast cancer accounts for 5-10% of all breast cancer cases. So far, known genetic risk factors account for only …
Article scientifique
Skin cancers in people with albinism in Togo in 2019: results of two rounds of national mobile skin care clinics
BACKGROUND: In people with albinism (PWA), the deficiency of melanin increase the risk of skin cancers. The aim of this …
Article scientifique
Analysis of global human gut metagenomes shows that metabolic resilience potential for short-chain fatty acid production is strongly influenced by lifestyle
High taxonomic diversity in non-industrial human gut microbiomes is often interpreted as beneficial; however, it is unclear if taxonomic diversity …
Article scientifique
N6-methyladenosine regulates ATM expression and downstream signaling
N6-methyladenosine (m6A) is the most abundant modification in eukaryotic mRNAs, which plays an important role in regulating multiple biological processes. …
Article scientifique
Breed Ancestry, Divergence, Admixture, and Selection Patterns of the Simbra Crossbreed
In this study, we evaluated an admixed South African Simbra crossbred population, as well as the Brahman (Indicine) and Simmental …
Article scientifique
Repeated surveying over 6 years reveals that fine-scale habitat variables are key to tropical mountain ant assemblage composition and functional diversity
High-altitude-adapted ectotherms can escape competition from dominant species by tolerating low temperatures at cooler elevations, but climate change is eroding …
Article scientifique
Effect of some non-genetic factors on the productivity and profitability of Holstein Friesian dairy cows
Background and Aim: Milk yield (MY) is one of the main factors that affect the economic profitability of dairy farms. …
Article scientifique
First detection of a plasmid-encoded New-Delhi metallo-beta-lactamase-1 (NDM-1) producing Acinetobacter baumannii using whole genome sequencing, isolated in a clinical setting in Benin
Abstract Background Carbapenem-resistant Acinetobacter baumannii is considered a top priority pathogen by the World Health Organization for combatting increasing antibiotic …
Article scientifique
Human whole genome sequencing in South Africa
The advent and evolution of next generation sequencing has considerably impacted genomic research. Until recently, South African researchers were unable …
Article scientifique
Thidiazuron-induced direct organogenesis from immature inflorescence of three date palm cultivars
BACKGROUND: Inflorescence explants of date palm proved to be a promising tool for micropropagation of elite cultivars or rare males …
Article scientifique
A fungus-eat-fungus world: Digitopodium, with particular reference to mycoparasites of the coffee leaf rust, Hemileia vastatrix
Digitopodium hemileiae was described originally in 1930 as Cladosporium hemileiae; growing as a mycoparasite of the coffee leaf rust (CLR), …
Article scientifique
Sequence Alignment Using Machine Learning-Based Needleman–Wunsch Algorithm
Biological pairwise sequence alignment can be used as a method for arranging two biological sequence characters to identify regions of …
Article scientifique
“Mine did not breastfeed”, mothers’ experiences in breastfeeding children aged 0 to 24 months with oral clefts in Uganda
BACKGROUND: Appropriate breastfeeding is vital for infant and young child nutrition. Annually, oral clefts affect 0.73 per 1000 children in …
Article scientifique
Isolation and identification of Bacillus thuringiensis strains native of the Eastern Province of Saudi Arabia
Abstract Background Bacillus thuringiensis (Bt) produces a group of δ-endotoxin proteins designated as cry toxins. No doubt that Bt isolates …