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Publications
4142 publication(s) trouvée(s)
Article scientifique
Fine scale human genetic structure in three regions of Cameroon reveals episodic diversifying selection
Inferences from genetic association studies rely largely on the definition and description of the underlying populations that highlight their genetic …
Article scientifique
Evaluation of the hepato-renal functions and antimicrobial activity of fatty amido benzoic acid synthesised from Citrullus colocynthis seed oil
Abstract Rapid progression in resistance to antimicrobial agents by pathogenic organisms is a serious concern. This study aimed to synthesize …
Article scientifique
Isolation of secondary metabolites from the mediterranean sponge species; Hemimycale columella and its biological properties
Abstract Despite the richness and biodiversity of invertebrates and algae in the Mediterranean Sea, these organisms are still poorly studied. …
Article scientifique
EgyGene GelAnalyzer4: a powerful image analysis software for one-dimensional gel electrophoresis
BACKGROUND: Gel image analysis is a cornerstone in electrophoresis-based experiments. Nature of the experiment determines the target of the analysis. …
Article scientifique
Exposure levels of radiofrequency magnetic fields and static magnetic fields in 1.5 and 3.0 T MRI units
Abstract Magnetic resonance imaging (MRI) staff is exposed to a complex mixture of electromagnetic fields from MRI units. Exposure to …
Article scientifique
A map of copy number variations in the Tunisian population: a valuable tool for medical genomics in North Africa
Copy number variation (CNV) is considered as the most frequent type of structural variation in the human genome. Some CNVs …
Article scientifique
A NOVEL DIMENSIONALITY REDUCTION APPROACH TO IMPROVE MICROARRAY DATA CLASSIFICATION
Cancer tumor prediction and diagnosis at an early stage has become a necessity in cancer research, as it provides an …
Article scientifique
Interleukin-18 and interferon-γ single nucleotide polymorphisms in Egyptian patients with tuberculosis
BACKGROUND: Interleukin-18 (IL-18) and interferon-γ (IFN-γ) are cytokines of crucial role in inflammation and immune reactions. There is a growing …
Article scientifique
Identification of a novel pathogenic variant in PALB2 and BARD1 genes by a multigene sequencing panel in triple negative breast cancer in Morocco
Pathogenic variants (PVs) in BRCA genes have been mainly associated with an increasing risk of triple negative breast cancer (TNBC). …
Article scientifique
Benign ethnic neutropenia in a South African population, and its association with HIV acquisition and adverse event reporting in an HIV vaccine clinical trial
Benign ethnic neutropenia (BEN) is defined as a neutrophil count of <1.5×109 cells/L in healthy individuals and is more common …
Article scientifique
Anti-c-myc cholesterol based lipoplexes as onco-nanotherapeutic agents in vitro
Background: Strategies aimed at inhibiting the expression of the c-myc oncogene could provide the basis for alternative cancer treatment. In …
Article scientifique
In silico analysis of promoter regions and regulatory elements (motifs and CpG islands) of the genes encoding for alcohol production in Saccharomyces cerevisiaea S288C and Schizosaccharomyces pombe 972h-
BACKGROUND: The crucial factor in the production of bio-fuels is the choice of potent microorganisms used in fermentation processes. Despite …
Article scientifique
Advanced molecular characterization of enteropathogenic Escherichia coli isolated from diarrheic camel neonates in Egypt
Background and Aim: Camels are important livestock in Egypt on cultural and economic bases, but studies of etiological agents of …
Article scientifique
Proceedings of an expert workshop on community agreement for gene drive research in Africa - Co-organised by KEMRI, PAMCA and Target Malaria
Gene drive research is progressing towards future field evaluation of modified mosquitoes for malaria control in sub-Saharan Africa. While many …
Article scientifique
Germline copy number variations in BRCA1/2 negative families: Role in the molecular etiology of hereditary breast cancer in Tunisia
Hereditary breast cancer accounts for 5-10% of all breast cancer cases. So far, known genetic risk factors account for only …
Article scientifique
Skin cancers in people with albinism in Togo in 2019: results of two rounds of national mobile skin care clinics
BACKGROUND: In people with albinism (PWA), the deficiency of melanin increase the risk of skin cancers. The aim of this …
Article scientifique
Analysis of global human gut metagenomes shows that metabolic resilience potential for short-chain fatty acid production is strongly influenced by lifestyle
High taxonomic diversity in non-industrial human gut microbiomes is often interpreted as beneficial; however, it is unclear if taxonomic diversity …
Article scientifique
N6-methyladenosine regulates ATM expression and downstream signaling
N6-methyladenosine (m6A) is the most abundant modification in eukaryotic mRNAs, which plays an important role in regulating multiple biological processes. …
Article scientifique
Breed Ancestry, Divergence, Admixture, and Selection Patterns of the Simbra Crossbreed
In this study, we evaluated an admixed South African Simbra crossbred population, as well as the Brahman (Indicine) and Simmental …
Article scientifique
Repeated surveying over 6 years reveals that fine-scale habitat variables are key to tropical mountain ant assemblage composition and functional diversity
High-altitude-adapted ectotherms can escape competition from dominant species by tolerating low temperatures at cooler elevations, but climate change is eroding …