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Publications
4601 publication(s) trouvée(s)
Article scientifique
Genome-wide In Silico Analysis, Characterization and Identification of Microsatellites in Spodoptera littoralis Multiple nucleopolyhedrovirus (SpliMNPV)
In this study, we undertook a survey to analyze the distribution and frequency of microsatellites or Simple Sequence Repeats (SSRs) …
Article scientifique
Indole-3- carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic study
Sorafenib is the only chemotherapeutic agent currently approved for unresectable hepatocellular carcinoma (HCC). However, poor response rates have been widely …
Article scientifique
Lebetin 2, a Snake Venom-Derived Natriuretic Peptide, Attenuates Acute Myocardial Ischemic Injury through the Modulation of Mitochondrial Permeability Transition Pore at the Time of Reperfusion
Cardiac ischemia is one of the leading causes of death worldwide. It is now well established that natriuretic peptides can …
Article scientifique
Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti
The NF-κB pathway has critical roles in cancer, immunity and inflammatory responses. Understanding the mechanism(s) by which mutations in genes …
Article scientifique
Low genetic diversity and recent demographic expansion in the red starfish Echinaster sepositus (Retzius 1816)
Understanding the phylogeography and genetic structure of populations and the processes responsible of patterns therein is crucial for evaluating the …
Article scientifique
Fine-tuning of amino sugar homeostasis by EIIANtr in Salmonella Typhimurium
The nitrogen-metabolic phosphotransferase system, PTS(Ntr), consists of the enzymes I(Ntr), NPr and IIA(Ntr) that are encoded by ptsP, ptsO, and …
Article scientifique
Simple and rapid detection of Tilletia horrida causing rice kernel smut in rice seeds
A simple and rapid method for the detection of Tilletia horrida, the causal agent of rice kernel smut, in rice …
Article scientifique
Microbes at Surface-Air Interfaces: The Metabolic Harnessing of Relative Humidity, Surface Hygroscopicity, and Oligotrophy for Resilience
The human environment is predominantly not aqueous, and microbes are ubiquitous at the surface-air interfaces with which we interact. Yet …
Article scientifique
Assessment of the response to cholera outbreaks in two districts in Ghana
BACKGROUND: Despite recurring outbreaks of cholera in Ghana, very little has been reported on assessments of outbreak response activities undertaken …
Article scientifique
Prevalence and multidrug resistance of Escherichia coli from community-acquired infections in Lagos, Nigeria
INTRODUCTION: The emergence of multidrug resistance (MDR; resistance to ≥ 2 more antimicrobials) in Escherichia coli is of concern due …
Article scientifique
Enteric pathogens and factors associated with acute bloody diarrhoea, Kenya
BACKGROUND: Shigellosis is the major cause of bloody diarrhoea worldwide and is endemic in most developing countries. In Kenya, bloody …
Article scientifique
The Lipopolysaccharide-Induced Metabolome Signature in Arabidopsis thaliana Reveals Dynamic Reprogramming of Phytoalexin and Phytoanticipin Pathways
Lipopolysaccharides (LPSs), as MAMP molecules, trigger the activation of signal transduction pathways involved in defence. Currently, plant metabolomics is providing …
Article scientifique
Semi-quantitative digital analysis of polymerase chain reactionelectrophoresis gel: Potential applications in low-income veterinary laboratories
AIM: The interpretation of conventional polymerase chain reaction (PCR) assay results is often limited to either positive or negative (non-detectable). …
Article scientifique
Longitudinal Comparison of Antibiotic Resistance in Diarrheagenic and Non-pathogenic Escherichia coli from Young Tanzanian Children
Enteroaggregative, enteropathogenic, and enterotoxigenic E. coli contribute significantly to the burden of diarrheal infections particularly in developing countries. Antibiotic resistance …
Article scientifique
Identification and statistical optimization of fermentation conditions for a newly isolated extracellular cholesterol oxidase-producing Streptomyces cavourensis strain NEAE-42
BACKGROUND: Due to broad range of clinical and industrial applications of cholesterol oxidase, isolation and screening of bacterial strains producing …
Article scientifique
Discovery of parvovirus-related sequences in an unexpected broad range of animals
Our knowledge of the genetic diversity and host ranges of viruses is fragmentary. This is particularly true for the Parvoviridae …
Article scientifique
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus
A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs …
Article scientifique
Bacillus cereus Biovar Anthracis Causing Anthrax in Sub-Saharan Africa—Chromosomal Monophyly and Broad Geographic Distribution
Through full genome analyses of four atypical Bacillus cereus isolates, designated B. cereus biovar anthracis, we describe a distinct clade …
Article scientifique
Current State of Resistance to Antibiotics of Last-Resort in South Africa: A Review from a Public Health Perspective
A review of the literature was undertaken to delineate the current level and mechanisms of resistance to carbapenems, colistin and …
Article scientifique
Deep sequencing reveals microbiota dysbiosis of tongue coat in patients with liver carcinoma
Liver carcinoma (LC) is a common malignancy worldwide, associated with high morbidity and mortality. Characterizing microbiome profiles of tongue coat …