308 publication(s) trouvée(s)
Article scientifique
Development of extended-release formulation of domperidone using a blend of Raphia hookeri gum and hydroxypropyl methylcellulose as tablet matrix
Purpose: To develop an extended-release formulation of domperidone using a blend of Raphia hookeri gum and hydroxypropyl methylcellulose as tablet …
Article scientifique
Construction and evaluation of a novel triple cell epitopebased polypeptide vaccine against cow mastitis induced by Staphylococcus aureus, Escherichia coli and Streptococcus
Purpose: To construct a novel triple cell epitope-based polypeptide vaccine against cow mastitis induced by Staphylococcus aureus, Escherichia coli and …
Article scientifique
Ginsenoside Rg1 improves ischemic brain injury by balancing mitochondrial biogenesis and mitophagy
Purpose: To study the effects of ginsenoside Rg1 on mitochondrial dysfunction induced by ischemic stroke.Methods: Human neuroblastoma SK-N-SH cells, subjected …
Article scientifique
In-silico design of novel myocilin inhibitors for glaucoma therapy
Purpose: To explore newer computational approaches in the design of novel myocilin inhibitors for the treatment of glaucoma.Methods: An in-silico …
Article scientifique
Preparation and characterization of artemether inclusion complexes with hydroxypropyl-β-cyclodextrin
Purpose: To investigate experimentally the inclusion of artemether into the cavity of hydroxypropyl-β-cyclodextrin and examine its effect on the solubility …
Article scientifique
Effects of atorvastatin and rosuvastatin on blood lipids, platelet aggregation rate and inflammatory factors in patients with cerebral infarction
Purpose: To investigate the effects of atorvastatin and rosuvastatin on blood lipids, platelet aggregation rate (PAR) and inflammatory factors in …
Article scientifique
Effect of Spatholobus suberectus (Fabaceae) extract on second-degree burns in rats
Purpose: To evaluate the wound-healing effect of Spatholobus suberectus (Fabaceae) on seconddegree burns in a rat model.Methods: The animals were …
Article scientifique
Anti-arthritic effect of total anthraquinone from Polygonum cuspidatum on type II collagen-induced arthritis in rats
Purpose: To study the anti-arthritic effect of total anthraquinone from Polygonum cuspidatum (TAPC) on type II collagen-induced arthritis (CIA) in …
Article scientifique
Development of a high performance liquid chromatography method for simultaneous analysis of theophylline, guaifenesin and diphenhydramine in an elixir
Purpose: To develop and validate a new low-cost high performance liquid chromatography (HPLC) method for simultaneous analysis of theophylline (TH), …
Article scientifique
In vivo anti-inflammatory activity of Liquidambar formosana Hance infructescence extract
Purpose: To evaluate the anti-inflammatory activity of Liquidambar formosana Hance infructescence (Liquidambaris fructus, ELF) in vivo, and clarify its underlying …
Article scientifique
Ethnomedicinal uses and pharmacological activities of Croton megalobotrys Mϋll Arg: A systematic review
Purpose: To provide an overview of the ethnomedicinal uses and pharmacological activities of Croton megalobotrys as to understand its potential …
Article scientifique
Stability and drug dissolution evaluation of Qingkailing soft/hard capsules based on multi-component quantification and fingerprint pattern statistical analysis
Purpose: To carry out a post-marketing evaluation of the stability and drug dissolution of Qingkailing soft/hard capsules.Methods: High performance liquid …
Article scientifique
Effectiveness of various non-steroidal anti-inflammatory drugs in pain management of patients with vertebral fracture: A comparative clinical study
Purpose: To study the effectiveness of various nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with vertebral fractures.Methods: A total of 78 …
Article scientifique
Structure-based drug design approach to target toll-like receptor signaling pathways for disease treatment
Toll-like receptor (TLR) signaling pathways are the first line of defence against many microbial organisms. The question of how TLRs …
Article scientifique
Curative role of lactulose, L-carnitine, alpha-lipoic acid and combination of L-carnitine and alpha-lipoic acid in a rat model of acute hepatic encephalopathy: Biochemical observations
Purpose: To determine whether a combination L-carnitine and α-lipoic acid (ALA) can alleviate the toxic effects of thioacetamide (TAA) via …
Article scientifique
Pharmacokinetics of a telmisartan, amlodipine and hydrochlorothiazide fixed-dose combination: A replicate crossover study in healthy Korean male subjects
Purpose: To compare the tolerability and pharmacokinetic profiles of telmisartan, amlodipine, and hydrochlorothiazide (HCTZ) in a fixed-dose combination (FDC, test …
Article scientifique
Mitigation of TGF-β/Smad signaling pathway-associated liver fibrosis by paeoniflorin
Purpose: To evaluate paeoniflorin (PF) as a possible protective agent against liver fibrosis and its likely mechanisms of action.Methods: A …
Article scientifique
Moringa oleifera: An apoptosis inducer in cancer cells
Moringa oleifera, usually called “wonderful tree”, has been scientifically proven to inhibit proliferation of many cancer cell types by induction …
Article scientifique
Preparation and physicochemical evaluation of transdermal aerosols containing ketoprofen
Purpose: To prepare transdermal ketoprofen metered-dose aerosol formulations containing menthol and isopropyl myristate (IPM) as penetration enhancers and to evaluate …
Article scientifique
Association between cystatin C and the interaction of pulmonary tuberculosis with chronic diseases
Purpose: To determine the association between Cystatin C (Cys C) levels and the interaction of pulmonary tuberculosis (PTB) with chronic …