148 publication(s) trouvée(s)
Article scientifique
Western tropical Pacific multidecadal variability forced by the Atlantic multidecadal oscillation
Observational analysis suggests that the western tropical Pacific (WTP) sea surface temperature (SST) shows predominant variability over multidecadal time scales, …
Article scientifique
Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions
Tissue architecture contributes to pancreatic ductal adenocarcinoma (PDAC) phenotypes. Cancer cells within PDAC form gland-like structures embedded in a collagen-rich …
Article scientifique
HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation
The human T-lymphotropic virus type 1 (HTLV-1) is efficiently transmitted through cellular contacts. While the molecular mechanisms of viral cell-to-cell …
Article scientifique
Nearest-neighbour resonating valence bonds in YbMgGaO4
Abstract Since its proposal by Anderson, resonating valence bonds (RVB) formed by a superposition of fluctuating singlet pairs have been …
Article scientifique
Pacific plate motion change caused the Hawaiian-Emperor Bend
A conspicuous 60° bend of the Hawaiian-Emperor Chain in the north-western Pacific Ocean has variously been interpreted as the result …
Article scientifique
IL-21-mediated reversal of NK cell exhaustion facilitates anti-tumour immunity in MHC class I-deficient tumours
During cancer immunoediting, loss of major histocompatibility complex class I (MHC-I) in neoplasm contributes to the evasion of tumours from …
Article scientifique
Genetic loci associated with heart rate variability and their effects on cardiac disease risk
Abstract Reduced cardiac vagal control reflected in low heart rate variability (HRV) is associated with greater risks for cardiac morbidity …
Article scientifique
Electronic metal-support interaction enhanced oxygen reduction activity and stability of boron carbide supported platinum
Catalysing the reduction of oxygen in acidic media is a standing challenge. Although activity of platinum, the most active metal, …
Article scientifique
Insufficient antibody validation challenges oestrogen receptor beta research
The discovery of oestrogen receptor β (ERβ/ESR2) was a landmark discovery. Its reported expression and homology with breast cancer pharmacological …
Article scientifique
Prevalence of sexual dimorphism in mammalian phenotypic traits
The role of sex in biomedical studies has often been overlooked, despite evidence of sexually dimorphic effects in some biological …
Article scientifique
Signalome-wide assessment of host cell response to hepatitis C virus
Host cell signalling during infection with intracellular pathogens remains poorly understood. Here we report on the use of antibody microarray …
Article scientifique
Underwater Leidenfrost nanochemistry for creation of size-tailored zinc peroxide cancer nanotherapeutics
The dynamic underwater chemistry seen in nature is inspiring for the next generation of eco-friendly nanochemistry. In this context, green …
Article scientifique
Transcriptomic and macroevolutionary evidence for phenotypic uncoupling between frog life history phases
Anuran amphibians undergo major morphological transitions during development, but the contribution of their markedly different life-history phases to macroevolution has …
Article scientifique
Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation
Targeting the specific metabolic phenotypes of colorectal cancer stem cells (CRCSCs) is an innovative therapeutic strategy for colorectal cancer (CRC) …
Article scientifique
Whole genome analysis of a schistosomiasis-transmitting freshwater snail
Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to …
Article scientifique
End-Triassic mass extinction started by intrusive CAMP activity
The end-Triassic extinction is one of the Phanerozoic's largest mass extinctions. This extinction is typically attributed to climate change associated …
Article scientifique
Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation
Environmental cues profoundly modulate cell proliferation and cell elongation to inform and direct plant growth and development. External phosphate (Pi) …
Article scientifique
A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density
In macromolecular crystallography, the rigorous detection of changed states (for example, ligand binding) is difficult unless signal is strong. Ambiguous …
Article scientifique
Wave-particle energy exchange directly observed in a kinetic Alfvén-branch wave
Alfvén waves are fundamental plasma wave modes that permeate the universe. At small kinetic scales, they provide a critical mechanism …
Article scientifique
Low-crystalline iron oxide hydroxide nanoparticle anode for high-performance supercapacitors
Abstract Carbon materials are generally preferred as anodes in supercapacitors; however, their low capacitance limits the attained energy density of …