758 publication(s) trouvée(s)
Article scientifique
Effect of LongRange™ eprinomectin on Anopheles arabiensis by feeding on calves treated with the drug
BACKGROUND: Misuse of long-lasting insecticidal nets together with resistance of vectors to most of the insecticides for indoor residual spraying …
Article scientifique
Differential expression of var subgroups and PfSir2a genes in afebrile Plasmodium falciparum malaria: a matched case–control study
BACKGROUND: Poor knowledge on the afebrile Plasmodium falciparum biology limits elimination approaches to target asymptomatic malaria. Therefore, the association of …
Article scientifique
Targeted Next Generation Sequencing for malaria research in Africa: current status and outlook
Targeted Next Generation Sequencing (TNGS) is an efficient and economical Next Generation Sequencing (NGS) platform and the preferred choice when …
Article scientifique
Intermittent preventive treatment of malaria delivered to primary schoolchildren provided effective individual protection in Jinja, Uganda: secondary outcomes of a cluster-randomized trial (START-IPT)
BACKGROUND: Intermittent preventive treatment (IPT) of malaria is recommended as policy for certain high-risk populations, but not currently for schoolchildren. …
Article scientifique
Getting ready for integrated vector management for improved disease prevention in Zimbabwe: a focus on key policy issues to consider
BACKGROUND: This paper outlines Zimbabwe's potential readiness in harnessing integrated vector management (IVM) strategy for enhanced control of vector-borne diseases. …
Article scientifique
Rare mutations in Pfmdr1 gene of Plasmodium falciparum detected in clinical isolates from patients treated with anti-malarial drug in Nigeria
BACKGROUND: Plasmodium falciparum, the deadliest causative agent of malaria, has high prevalence in Nigeria. Drug resistance causing failure of previously …
Article scientifique
Plasmodium vivax cerebral malaria in an adult patient in Sudan
BACKGROUND: Plasmodium vivax infection is rising in sub-Saharan Africa, where Plasmodium falciparum is responsible for more than 90% of malaria …
Article scientifique
Net age, but not integrity, may be associated with decreased protection against Plasmodium falciparum infection in southern Malawi
BACKGROUND: Distribution campaigns for insecticide-treated nets (ITN) have increased the use of ITNs in Malawi, but malaria prevalence remains high …
Article scientifique
Deployment and utilization of next-generation sequencing of Plasmodium falciparum to guide anti-malarial drug policy decisions in sub-Saharan Africa: opportunities and challenges
Parasite resistance against anti-malarial drugs is a major threat to the ongoing malaria control and elimination strategies. This is especially …
Article scientifique
Impact of Plasmodium falciparum malaria and intermittent preventive treatment of malaria in pregnancy on the risk of malaria in infants: a systematic review
BACKGROUND: Studies of the association between malaria in pregnancy (MiP) and malaria during infancy have provided mixed results. A systematic …
Article scientifique
Malaria around large dams in Africa: effect of environmental and transmission endemicity factors
BACKGROUND: The impact of large dams on malaria has received widespread attention. However, understanding how dam topography and transmission endemicity …
Article scientifique
Poverty and food security: drivers of insecticide-treated mosquito net misuse in Malawi
BACKGROUND: Over the past decade, food insecurity, connected to erratic rains and reduced agricultural outputs, has plagued Malawi. Many households …
Article scientifique
Eave ribbons treated with transfluthrin can protect both users and non-users against malaria vectors
BACKGROUND: Eave ribbons treated with spatial repellents effectively prevent human exposure to outdoor-biting and indoor-biting malaria mosquitoes, and could constitute …
Article scientifique
Extent of inappropriate prescription of artemisinin and anti-malarial injections to febrile outpatients, a cross-sectional analytic survey in the Greater Accra region, Ghana
BACKGROUND: Febrile children seen in malaria hypo-endemic settings, such as the Greater Accra region (GAR) of Ghana are more likely …
Article scientifique
Reduction of malaria vector mosquitoes in a large-scale intervention trial in rural Burkina Faso using Bti based larval source management
BACKGROUND: Malaria remains one of the most important causes of morbidity and death in sub-Saharan Africa. Along with early diagnosis …
Article scientifique
Applying next-generation sequencing to track falciparum malaria in sub-Saharan Africa
Next-generation sequencing (NGS) technologies are increasingly being used to address a diverse range of biological and epidemiological questions. The current …
Article scientifique
The impact on malaria of biannual treatment with azithromycin in children age less than 5 years: a prospective study
BACKGROUND: The MORDOR study, a cluster randomized clinical trial, showed that single-dose azithromycin (20 mg/kg) administered biannually for 2 years …
Article scientifique
Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag
BACKGROUND: Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) antigens play a critical role in host immune evasion. Serologic responses to these …
Article scientifique
Are k13 and plasmepsin II genes, involved in Plasmodium falciparum resistance to artemisinin derivatives and piperaquine in Southeast Asia, reliable to monitor resistance surveillance in Africa?
Mutations in the propeller domain of Plasmodium falciparum kelch 13 (Pfk13) gene are associated with artemisinin resistance in Southeast Asia. …
Article scientifique
Implementing population-based mass drug administration for malaria: experience from a high transmission setting in North Eastern Uganda
BACKGROUND: Mass drug administration (MDA) is a suggested mean to accelerate efforts towards elimination and attainment of malaria-free status. There …