750 publication(s) trouvée(s)
Article scientifique
Systematic review of the status of pfhrp2 and pfhrp3 gene deletion, approaches and methods used for its estimation and reporting in Plasmodium falciparum populations in Africa: review of published studies 2010–2019
BACKGROUND: Malaria rapid diagnostic tests based on histidine-rich protein-2 have played a vital role in improving malaria case management and …
Article scientifique
The economic burden of malaria on households and the health system in a high transmission district of Mozambique
BACKGROUND: Malaria remains a leading cause of morbidity and mortality in Mozambique. Increased investments in malaria control have reduced the …
Article scientifique
There should be a World Health Assembly resolution for malaria eradication
Several efforts are being made now for malaria elimination with a goal for eradication. New tools and strategies are being …
Article scientifique
Bio-efficacy and wash resistance of MAGNet long-lasting insecticidal net against wild populations of Anopheles funestus in experimental huts in Muheza, Tanzania
BACKGROUND: The decline in malaria cases and vectors is major milestone in fighting against malaria. The efficacy of MAGNet long-lasting …
Article scientifique
Triple artemisinin-containing combination anti-malarial treatments should be implemented now to delay the emergence of resistance: the case against
Managing multidrug resistant malaria can be problematic if currently available artemisinin-containing anti-malarial combination treatments are not used appropriately. Here, I …
Article scientifique
Mosquitoes as a feasible sentinel group for anti-malarial resistance surveillance by Next Generation Sequencing of Plasmodium falciparum
BACKGROUND: Plasmodium falciparum drug resistance surveillance is key to successful disease control and eradication. Contemporary methods that only allow determination …
Article scientifique
DNA recovery from archived RDTs for genetic characterization of Plasmodium falciparum in a routine setting in Lambaréné, Gabon
BACKGROUND: Rapid diagnostic tests (RDTs) have been described as a source of genetic material to analyse malaria parasites in proof-of-concept …
Article scientifique
Genetic polymorphism of the N-terminal region in circumsporozoite surface protein of Plasmodium falciparum field isolates from Sudan
BACKGROUND: Malaria caused by Plasmodium falciparum parasite is still known to be one of the most significant public health problems …
Article scientifique
Prevalence and distribution of G6PD deficiency: implication for the use of primaquine in malaria treatment in Ethiopia
BACKGROUND: G6PD enzyme deficiency is a common enzymatic X-linked disorder. Deficiency of the G6PD enzyme can cause free radical-mediated oxidative …
Article scientifique
Ultrasensitive loop mediated isothermal amplification (US-LAMP) to detect malaria for elimination
BACKGROUND: Malaria elimination requires diagnostic methods able to detect parasite levels well below what is currently possible with microscopy and …
Article scientifique
Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquine
BACKGROUND: A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This …
Article scientifique
Detection of malaria parasites in dried human blood spots using mid-infrared spectroscopy and logistic regression analysis
BACKGROUND: Epidemiological surveys of malaria currently rely on microscopy, polymerase chain reaction assays (PCR) or rapid diagnostic test kits for …
Article scientifique
Effect of LongRange™ eprinomectin on Anopheles arabiensis by feeding on calves treated with the drug
BACKGROUND: Misuse of long-lasting insecticidal nets together with resistance of vectors to most of the insecticides for indoor residual spraying …
Article scientifique
Differential expression of var subgroups and PfSir2a genes in afebrile Plasmodium falciparum malaria: a matched case–control study
BACKGROUND: Poor knowledge on the afebrile Plasmodium falciparum biology limits elimination approaches to target asymptomatic malaria. Therefore, the association of …
Article scientifique
Targeted Next Generation Sequencing for malaria research in Africa: current status and outlook
Targeted Next Generation Sequencing (TNGS) is an efficient and economical Next Generation Sequencing (NGS) platform and the preferred choice when …
Article scientifique
Intermittent preventive treatment of malaria delivered to primary schoolchildren provided effective individual protection in Jinja, Uganda: secondary outcomes of a cluster-randomized trial (START-IPT)
BACKGROUND: Intermittent preventive treatment (IPT) of malaria is recommended as policy for certain high-risk populations, but not currently for schoolchildren. …
Article scientifique
Getting ready for integrated vector management for improved disease prevention in Zimbabwe: a focus on key policy issues to consider
BACKGROUND: This paper outlines Zimbabwe's potential readiness in harnessing integrated vector management (IVM) strategy for enhanced control of vector-borne diseases. …
Article scientifique
Rare mutations in Pfmdr1 gene of Plasmodium falciparum detected in clinical isolates from patients treated with anti-malarial drug in Nigeria
BACKGROUND: Plasmodium falciparum, the deadliest causative agent of malaria, has high prevalence in Nigeria. Drug resistance causing failure of previously …
Article scientifique
Plasmodium vivax cerebral malaria in an adult patient in Sudan
BACKGROUND: Plasmodium vivax infection is rising in sub-Saharan Africa, where Plasmodium falciparum is responsible for more than 90% of malaria …
Article scientifique
Net age, but not integrity, may be associated with decreased protection against Plasmodium falciparum infection in southern Malawi
BACKGROUND: Distribution campaigns for insecticide-treated nets (ITN) have increased the use of ITNs in Malawi, but malaria prevalence remains high …