69 publication(s) trouvée(s)
Article scientifique
Scaffold Diversity of Fungal Metabolites
Many drug discovery projects rely on commercial compounds to discover active leads. However, current commercial libraries, with mostly synthetic compounds, …
Article scientifique
Dexamethasone Pretreatment Alleviates Isoniazid/Lipopolysaccharide Hepatotoxicity: Inhibition of Inflammatory and Oxidative Stress
Isoniazid (INH) remains a cornerstone key constitute of the current tuberculosis management strategy, but its hepatotoxic potentiality remains a significant …
Article scientifique
Biomarkers Associated with Cognitive Impairment in Treated Cancer Patients: Potential Predisposition and Risk Factors
Purpose: Cognitive impairment in cancer patients induced, at least in part, by treatment are frequently observed and likely have negative …
Article scientifique
Lead Induced Hepato-renal Damage in Male Albino Rats and Effects of Activated Charcoal
Lead is a multi-organ toxicant implicated in various cancers, diseases of the hepatic, renal, and reproductive systems etc. In search …
Article scientifique
ROK and Arteriolar Myogenic Tone Generation: Molecular Evidence in Health and Disease
The myogenic response is an inherent property of resistance arteries that warrants a relatively constant blood flow in response to …
Article scientifique
HLA-B*57 Allele Is Associated with Concomitant Anti-tuberculosis and Antiretroviral Drugs Induced Liver Toxicity in Ethiopians
Drug-induced liver injury (DILI) is a known adverse effect of both anti-tuberculosis (anti-TB) and antiretroviral (ARV) drugs. Recent studies highlight …
Article scientifique
Hyperuricemia in Children and Adolescents with Autism Spectrum Disorder Treated with Risperidone: The Risk Factors for Metabolic Adverse Effects
Background: Atypical antipsychotics have been found to be associated with hyperuricemia. Risperidone, one of the atypical antipsychotics, might be related …
Article scientifique
Delayed Chemotherapy-Induced Nausea and Vomiting: Pathogenesis, Incidence, and Current Management
Even when chemotherapy-induced nausea and vomiting (CINV) can be effectively controlled in the acute phase, it may still occur in …
Article scientifique
The Role of Eukaryotic and Prokaryotic ABC Transporter Family in Failure of Chemotherapy
Over the years chemotherapy failure has been a vital research topic as researchers have been striving to discover reasons behind …