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Publications
3505 publication(s) trouvée(s)
Article scientifique
Probing the Structural Dynamics of the Plasmodium falciparum Tunneling-Fold Enzyme 6-Pyruvoyl Tetrahydropterin Synthase to Reveal Allosteric Drug Targeting Sites
The folate de novo synthesis pathway is a well-established drug target in the treatment of many infectious diseases. Antimalarial antifolate …
Article scientifique
β-lactamases (bla TEM, bla SHV, bla CTXM-1, bla VEB, bla OXA-1) and class C β-lactamases gene frequency in Pseudomonas aeruginosa isolated from various clinical specimens in Khartoum State, Sudan: a cross sectional study
Background: Pseudomonas aeruginosa is a pathogenic bacterium, causing nosocomial infections with intrinsic and acquired resistance mechanisms to a large group …
Article scientifique
Attenuation of Rat Colon Carcinogenesis by Styela plicata Aqueous Extract. Modulation of NF-κB Pathway and Cytoplasmic Sod1 Gene Expression
OBJECTIVE: In search for a unique natural combination of highly active biological components for treatment against colon cancer, we used …
Article scientifique
Thermodynamic and detailed kinetic study of the formation of orthophthalaldehyde-agmatine complex by fluorescence intensities
Abstract The aim of this work is to determine the thermodynamic parameters and the kinetics of complex formation between orthophthalaldehyde …
Article scientifique
A Department of Defense Laboratory Consortium Approach to Next Generation Sequencing and Bioinformatics Training for Infectious Disease Surveillance in Kenya
Epidemics of emerging and re-emerging infectious diseases are a danger to civilian and military populations worldwide. Health security and mitigation …
Article scientifique
Effect of lupeol from Vernonia glaberrima (Asteraceae) on pain and inflammation
Background: Steroids have been reported to possess analgesic and anti-inflammatory activities, and Vernonia glaberrima also possesses analgesic and anti-inflammatory properties. …
Article scientifique
Genotyping and Virulence Analysis of Drug Resistant Clinical Klebsiella pneumoniae Isolates in Egypt
Klebsiella pneumoniae is a highly drug-resistant human pathogen responsible for a variety of serious infections. Integrons, mobile genetic elements capable …
Article scientifique
Probing hidden diversity to enhance conservation of the endangered narrow-range endemic Eastern Cape rocky, Sandelia bainsii (Castelnau 1861)
No abstract available.
Article scientifique
Comparative molecular genetic diversity between Trichoderma spp. from Egypt and Saudi Arabia
Abstract Background The phylogeny and phylogenetic relationships of Trichoderma species were investigated by many methods including maximum parsimony and distance …
Article scientifique
Genome-wide genetic diversity and population structure of Garcinia kola (Heckel) in Benin using DArT-Seq technology
Garcinia kola (Heckel) is a versatile tree indigenous to West and Central Africa. All parts of the tree have value …
Article scientifique
Impact of emamectin benzoate on nucleopolyhedrosis virus infectivity of Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae)
Abstract Background Attempts based on increasing the efficacy of Baculovirus and/or reducing the application concentration of synthetic insecticides through integrated …
Article scientifique
Ethnic and Adipose Depot Specific Associations Between DNA Methylation and Metabolic Risk
Background Metabolic risk varies according to body mass index (BMI), body fat distribution and ethnicity. In recent years, epigenetics, which …
Article scientifique
Identification of single nucleotide variants in the Moroccan population by whole-genome sequencing
BACKGROUND: Large-scale human sequencing projects have described around a hundred-million single nucleotide variants (SNVs). These studies have predominately involved individuals …
Article scientifique
Clinical Significance of Annexin A4 as a Biomarker in the Early Diagnosis of Hepatocellular Carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most prevalent cancer worldwide. Early detection of HCC is crucial to improve …
Article scientifique
CRISPR-mediated gene modification of hematopoietic stem cells with beta-thalassemia IVS-1-110 mutation
Abstract Background β-Thalassemias represent a group of genetic disorders caused by human hemoglobin beta (HBB) gene mutations. The radical curative …
Article scientifique
Supporting Fisheries Management With Genomic Tools: A Case Study of Kingklip (Genypterus capensis) Off Southern Africa
Kingklip, Genypterus capensis, is one of southern Africa’s most valuable demersal fisheries resources, with a wide geographic distribution spanning South …
Article scientifique
Low frequency of enterohemorrhagic, enteroinvasive and diffusely adherent Escherichia coli in children under 5 years in rural Mozambique: a case-control study
BACKGROUND: Diarrheagenic Escherichia coli (DEC) are among the leading pathogens associated with endemic diarrhea in low income countries. Yet, few …
Article scientifique
Mesenchymal Stem Cells and Their Extracellular Vesicles: A Potential Game Changer for the COVID-19 Crisis
Corona virus disease 2019 (COVID-19) is a global public health crisis. The high infectivity of the disease even from non-symptomatic …
Article scientifique
Can CRISPR/Cas Technology Be a Felicitous Stratagem Against the COVID-19 Fiasco? Prospects and Hitches
The current global debacle of COVID-19, spelled by SARS-CoV-2 needs no elaboration. With incessant and constantly clambering number of deaths …
Article scientifique
Call order within vocal sequences of meerkats contains temporary contextual and individual information
BACKGROUND: The ability to recombine smaller units to produce infinite structures of higher-order phrases is unique to human language, yet …