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Publications
4601 publication(s) trouvée(s)
Article scientifique
Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer
BACKGROUND: A major hurdle incurrent to the human clinical application of conditionally replicative adenovirus (CRAd)-based virotherapy agents is their limited …
Article scientifique
Population structure and genetic trends for indigenous African beef cattle breeds in South Africa
The aim of this study was to investigate population structure and genetic trends based on pedigree and performance records of …
Article scientifique
In vitro toxicity determination of antifungal constituents from Combretum zeyheri
BACKGROUND: Candida albicans is one of the organisms living on the human body symbiotically, but, in hosts with low immunity …
Article scientifique
Chelatococcus thermostellatus sp. nov., a new thermophile for bioplastic synthesis: comparative phylogenetic and physiological study
The poly(3-hydroxybutyrate), PHB, accumulating thermophilic strain MW9(T), isolated from an aerobic organic waste treatment plant, was characterized by detailed physiological …
Article scientifique
Protective roles of free avian respiratory macrophages in captive birds
In the mammalian lung, respiratory macrophages provide front line defense against invading pathogens and particulate matter. In birds, respiratory macrophages …
Article scientifique
Plague in Arab Maghreb, 1940–2015: A Review
We reviewed the epidemiology of 49 plague outbreaks that resulted in about 7,612 cases in 30 localities in the Arabic …
Article scientifique
Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair
Histone demethylases have recently gained interest as potential targets in cancer treatment and several histone demethylases have been implicated in …
Article scientifique
DNA barcoding of Clarias gariepinus, Coptodon zillii and Sarotherodon melanotheron from Southwestern Nigeria
DNA barcoding has been adopted as a gold standard rapid, precise and unifying identification system for animal species and provides …
Article scientifique
Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosis
There is an urgent need to identify new treatments for tuberculosis (TB), a major infectious disease caused by Mycobacterium tuberculosis …
Article scientifique
Neonatal infections with multidrug-resistant ESBL-producing E. cloacae and K. pneumoniae in Neonatal Units of two different Hospitals in Antananarivo, Madagascar
BACKGROUND: We investigated the molecular mechanism of ß-lactam resistance in extended-spectrum ß-lactamase (ESBL)-producing Enterobacterial strains isolated in neonatal units of …
Article scientifique
Identification of two new keratinolytic proteases from a Bacillus pumilus strain using protein analysis and gene sequencing
The Bacillus strain (CCUG 66887) has a high capacity to excrete keratinase with the ability to degrade both alpha- and …
Article scientifique
Differential RNA-seq, Multi-Network Analysis and Metabolic Regulation Analysis of Kluyveromyces marxianus Reveals a Compartmentalised Response to Xylose
We investigated the transcriptomic response of a new strain of the yeast Kluyveromyces marxianus, in glucose and xylose media using …
Article scientifique
IMA Genome-F 6
The genomes of Armillaria fuscipes, Ceratocystiopsis minuta, Ceratocystis adiposa, Endoconidiophora laricicola, E. polonica, and Penicillium freii DAOMC 242723 are presented …
Article scientifique
A phylogenetic revision of Penicillium sect. Exilicaulis, including nine new species from fynbos in South Africa
A survey of the fynbos biome in South Africa resulted in the isolation of 61 Penicillium species from Protea repens …
Article scientifique
Intron Derived Size Polymorphism in the Mitochondrial Genomes of Closely Related Chrysoporthe Species
In this study, the complete mitochondrial (mt) genomes of Chrysoporthe austroafricana (190,834 bp), C. cubensis (89,084 bp) and C. deuterocubensis …
Article scientifique
Designing, construction and characterization of genetically encoded FRET-based nanosensor for real time monitoring of lysine flux in living cells
BACKGROUND: Engineering microorganisms in order to improve the metabolite flux needs a detailed knowledge of the concentrations and flux rates …
Article scientifique
A case of fatal Type I congenital disorders of glycosylation (CDG I) associated with low dehydrodolichol diphosphate synthase (DHDDS) activity
BACKGROUND: Type I congenital disorders of glycosylation (CDG-I) are mostly complex multisystemic diseases associated with hypoglycosylated serum glycoproteins. A subgroup …
Article scientifique
Efficient production of acetoin in Saccharomyces cerevisiae by disruption of 2,3-butanediol dehydrogenase and expression of NADH oxidase
Acetoin is widely used in food and cosmetic industry as taste and fragrance enhancer. For acetoin production in this study, …
Article scientifique
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus
BACKGROUND: Multiple recent genome-wide association studies (GWAS) have identified a single nucleotide polymorphism (SNP), rs10771399, at 12p11 that is associated …
Article scientifique
Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis
ATP-binding cassette transporter A1 (ABCA1) plays a critical role in maintaining cellular cholesterol homeostasis. The purpose of this study is …