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Publications
4492 publication(s) trouvée(s)
Article scientifique
Ethical, social, and cultural issues related to clinical genetic testing and counseling in low- and middle-income countries: protocol for a systematic review
BACKGROUND: There has been little focus in the literature on how to build genetic testing and counseling services in low- …
Article scientifique
Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome
Background: Many pathogens secrete effector molecules to subvert host immune responses, to acquire nutrients, and/or to prepare host cells for …
Article scientifique
A Novel View on the Role of Intracellular Tails in Surface Delivery of the Potassium-Chloride Cotransporter KCC2
A plethora of neurological disorders are associated with alterations in the expression and localization of potassium-chloride cotransporter type 2 (KCC2), …
Article scientifique
Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotides
Abstract Medical means to save the life of human patients affected by drug abuse, envenomation or critical poisoning are currently …
Article scientifique
Multidrug resistant bacteria are sensitive to Euphorbia prostrata and six others Cameroonian medicinal plants extracts
BACKGROUND: Multidrug resistant (MDR) bacteria are responsible for therapeutic failure and there is an urgent need for novels compounds efficient …
Article scientifique
Does genetic structure reflect differences in non-breeding movements? A case study in small, highly mobile seabirds
BACKGROUND: In seabirds, the extent of population genetic and phylogeographic structure varies extensively among species. Genetic structure is lacking in …
Article scientifique
Assessment of Hepatocellular Carcinoma Metastasis Glycobiomarkers Using Advanced Quantitative N-glycoproteome Analysis
Hepatocelluar carcinoma (HCC) is one of the most common malignant tumors with high incidence of metastasis. Glycosylation is involved in …
Article scientifique
Identification of long non-coding RNA in the horse transcriptome
BACKGROUND: Efforts to resolve the transcribed sequences in the equine genome have focused on protein-coding RNA. The transcription of the …
Article scientifique
Evidence for prehistoric origins of the G2019S mutation in the North African Berber population
The most common cause of the monogenic form of Parkinson's disease known so far is the G2019S mutation of the …
Article scientifique
Review of Antibiotic Resistance in the Indian Ocean Commission: A Human and Animal Health Issue
Antimicrobial Resistance (AMR) is a major threat to human, animal health and environment worldwide. For human, transmission occurred through a …
Article scientifique
Detection and quantitation of copy number variation in the voltage-gated sodium channel gene of the mosquito Culex quinquefasciatus
Insecticide resistance is typically associated with alterations to the insecticidal target-site or with gene expression variation at loci involved in …
Article scientifique
Snoopy’s hybrid simulator: a tool to construct and simulate hybrid biological models
BACKGROUND: Hybrid simulation of (computational) biochemical reaction networks, which combines stochastic and deterministic dynamics, is an important direction to tackle …
Article scientifique
Tumor-targeted delivery of siRNA using fatty acyl-CGKRK peptide conjugates
Tumor-targeted carriers provide efficient delivery of chemotherapeutic agents to tumor tissue. CGKRK is one of the well-known tumor targeting peptides …
Article scientifique
New hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres
The synthesis and molecular characterization of new isatin-based hydrazonoindolin-2-ones 4a-o and 7a-e are reported. The in vitro anti-proliferative potential of …
Article scientifique
Cutaneous Microbial Community Variation across Populations of Eastern Hellbenders (Cryptobranchus alleganiensis alleganiensis)
Multicellular hosts maintain complex associations with microbial communities. While microbial communities often serve important functional roles for their hosts, our …
Article scientifique
All-printed highly sensitive 2D MoS2 based multi-reagent immunosensor for smartphone based point-of-care diagnosis
Abstract Immunosensors are used to detect the presence of certain bio-reagents mostly targeted at the diagnosis of a condition or …
Article scientifique
Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity
Prions, characterized by self-propagating protease-resistant prion protein (PrP) conformations, are agents causing prion disease. Recent studies generated several such self-propagating …
Article scientifique
Highly diverse and antimicrobial susceptible Escherichia coli display a naïve bacterial population in fruit bats from the Republic of Congo
Bats are suspected to be a reservoir of several bacterial and viral pathogens relevant to animal and human health, but …
Article scientifique
Discovery of monoclonal antibodies cross-reactive to novel subserotypes of K. pneumoniae O3
Klebsiella pneumoniae is responsible for nosocomial infections causing significant morbidity and mortality. Treatment of newly emerging multi-drug resistant strains is …
Article scientifique
Genotypic diversity among multidrug resistant Pseudomonas aeruginosa and Acinetobacter species at Mulago Hospital in Kampala, Uganda
BACKGROUND: Multidrug resistant Pseudomonas aeruginosa and Acinetobacter species are common causes of nosocomial infections worldwide. Recently we reported the occurrence …