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4367 publication(s) trouvée(s)
Article scientifique
MALDI-TOF MS identification of Anopheles gambiae Giles blood meal crushed on Whatman filter papers
BACKGROUND: Identification of the source of mosquito blood meals is an important component for disease control and surveillance. Recently, matrix-assisted …
Article scientifique
Expression optimization of a cell membrane-penetrating human papillomavirus type 16 therapeutic vaccine candidate in Nicotiana benthamiana
High-risk human papillomaviruses (hr-HPVs) cause cervical cancer, the fourth most common cancer in women worldwide. A HPV-16 candidate therapeutic vaccine, …
Article scientifique
Gene Expression in Class 2 Integrons Is SOS-Independent and Involves Two Pc Promoters
Integrons are powerful bacterial genetic elements that permit the expression and dissemination of antibiotic-resistance gene cassettes. They contain a promoter …
Article scientifique
Endoglin inhibition leads to intussusceptive angiogenesis via activation of factors related to COUP-TFII signaling pathway
Angiogenesis is a highly coordinated, extremely complex process orchestrated by multiple signaling molecules and blood flow conditions. While sprouting mode …
Article scientifique
Identifying highly informative genetic markers for quantification of ancestry proportions in crossbred sheep populations: implications for choosing optimum levels of admixture
Understanding the relationship between genetic admixture and performances is crucial for the success of crossbreeding programs. Use of small sets …
Article scientifique
Breast cancer in Angola, molecular subtypes: a first glance
PURPOSE: The aim of this study was to investigate the breast cancer (BC) molecular subtypes according to its surrogate immunohistochemistry …
Article scientifique
Bone mineral density and risk of type 2 diabetes and coronary heart disease: A Mendelian randomization study
Background: Observational studies have demonstrated that increased bone mineral density is associated with a higher risk of type 2 diabetes …
Article scientifique
The neglected burden of snakebites in Cameroon: a review of the epidemiology, management and public health challenges
OBJECTIVES: Snakebite is an underestimated medical and surgical emergency in developing countries responsible for a high disease burden. Optimal management …
Article scientifique
A case report: primary amoebic meningoencephalitis in a young Zambian adult
BACKGROUND: Primary amoebic meningoencephalitis (PAM) is a fulminant disease of the brain caused by Naegleria fowleri. Although the disease is …
Article scientifique
Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos
Hypertension prevalence varies between ethnic groups, possibly due to differences in genetic, environmental, and cultural determinants. Hispanic/Latino Americans are a …
Article scientifique
Small molecule-based lineage switch of human adipose-derived stem cells into neural stem cells and functional GABAergic neurons
Cellular reprogramming using small molecules (SMs) without genetic modification provides a promising strategy for generating target cells for cell-based therapy. …
Article scientifique
Programmed cell death in Acanthamoeba castellanii Neff induced by several molecules present in olive leaf extracts
Therapy against Acanthamoeba infections such as Granulomatous Amoebic Encephalitis (GAE) and Acanthamoeba Keratitis (AK), remains as an issue to be …
Article scientifique
An intra-population analysis of the indris’ song dissimilarity in the light of genetic distance
The increasing interest in the evolution of human language has led several fields of research to focus on primate vocal …
Article scientifique
The Activity of the Neutral Sphingomyelinase Is Important in T Cell Recruitment and Directional Migration
Breakdown of sphingomyelin as catalysed by the activity of sphingomyelinases profoundly affects biophysical properties of cellular membranes which is particularly …
Article scientifique
High Spatial and Temporal Variations of Microbial Community along the Southern Catfish Gastrointestinal Tract: Insights into Dynamic Food Digestion
The fish intestinal microbiota is affected by dietary shifts or diet-related seasonal fluctuations making it highly variable and dynamic. It …
Article scientifique
Altitudinal gradients, biogeographic history and microhabitat adaptation affect fine-scale spatial genetic structure in African and Neotropical populations of an ancient tropical tree species
The analysis of fine-scale spatial genetic structure (FSGS) within populations can provide insights into eco-evolutionary processes. Restricted dispersal and locally …
Article scientifique
Visual adaptation in Lake Victoria cichlid fishes: depth-related variation of color and scotopic opsins in species from sand/mud bottoms
BACKGROUND: For Lake Victoria cichlid species inhabiting rocky substrates with differing light regimes, it has been proposed that adaptation of …
Article scientifique
Classes 1 and 2 integrons in faecal Escherichia coli strains isolated from mother-child pairs in Nigeria
BACKGROUND: Antimicrobial resistance among enteric bacteria in Africa is increasingly mediated by integrons on horizontally acquired genetic elements. There have …
Article scientifique
The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells
Nature has provided us with a wide spectrum of disease healing phytochemicals like Artonin E, obtained from the root bark …
Article scientifique
Characterization and RNAi-mediated knockdown of Chitin Synthase A in the potato tuber moth, Phthorimaea operculella
Chitin is a major component of insect exoskeleton, tracheal system and gut where it is synthesized by chitin synthase (CHS) …