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4348 publication(s) trouvée(s)
Article scientifique
Screening of nucleotide variations in genomic sequences encoding charged protein regions in the human genome
BACKGROUND: Studying genetic variation distribution in proteins containing charged regions, called charge clusters (CCs), is of great interest to unravel …
Article scientifique
Boosting isoprene production via heterologous expression of the Kudzu isoprene synthase gene (kIspS) into Bacillus spp. cell factory
Isoprene represents a key building block for the production of valuable materials such as latex, synthetic rubber or pharmaceutical precursors …
Article scientifique
Evaluation of the impact of Illumina error correction tools on de novo genome assembly
BACKGROUND: Recently, many standalone applications have been proposed to correct sequencing errors in Illumina data. The key idea is that …
Article scientifique
Leucine zipper transcription factor-like 1 expression in gastric cancer and its relationship to relative adhesion molecule
Purpose: To evaluate the expression of leucine zipper transcription factor-like1 (LZTFL1) molecule in the gastric cancer tissues, and its relationship …
Article scientifique
Effect of polygonimitin C on bone formation and resorption in human osteoblast-like MG63 cells
Purpose: To investigate the effect of polygonimitin C (PC) on bone formation and resorption in human osteoblast-like MG63 cells.Methods: MG63 …
Article scientifique
Chemo-enzymatic synthesis of Neu5Gc-containing sialylated lactulose
Purpose: To synthesize novel sialylated lactuloses, namely, Neu5Gc-α2,3-lactulose and Neu5Gc-α2,6-lactulose.Methods: ManNGc was chemically synthesized from commercially available N-acetylmannosaime (ManNAc), which …
Article scientifique
A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress
BACKGROUND: Mantle cell lymphoma (MCL) is a B-cell hemopathy characterized by the t(11;14) translocation and the aberrant overexpression of cyclin …
Article scientifique
Comparative analysis of hyoscine in wild-type and in vitro grown Datura innoxia by high performance liquid chromatography
Purpose: To compare the hyoscine contents of Datura innoxia plant grown in the wild and that grown in vitro.Methods: For …
Article scientifique
Fourteen simple-sequence repeats newly developed for population genetic studies in Prosopis africana (Fabaceae–Mimosoideae)
BACKGROUND: There is very limited genetic knowledge in Prosopis africana, an important sub-Saharan multi-purpose tree species. Availability of highly polymorphic …
Article scientifique
Monoallelic characteristic-bearing heterozygous L1053X in BRCA2 gene among Sudanese women with breast cancer
BACKGROUND: Breast cancer (BC) is the most common type of cancer in women. Among many risk factors of BC, mutations …
Article scientifique
Potential of Health and Demographic Surveillance System in Asthma and Chronic Obstructive Pulmonary Disease Microbiome Research
Health and demographic surveillance system (HDSS) is a population-based health and vital event registration system that monitors demographic and health …
Article scientifique
Genetic analysis of milk production traits of Tunisian Holsteins using random regression test-day model with Legendre polynomials
OBJECTIVE: The objective of this study was to estimate genetic parameters of milk, fat, and protein yields within and across …
Article scientifique
Styrene maleic acid encapsulated raloxifene micelles for management of inflammatory bowel disease
BACKGROUND: Inflammatory bowel disease (IBD) comprises a group of disorders that manifest through chronic inflammation of the colon and small …
Article scientifique
Antimicrobial activity of ethyl acetate extract of Citrullus lanatus seeds
Purpose: To determine the antimicrobial activity and chemical constituents of ethyl acetate extract of Citrullus lanatus seeds.Methods: Antimicrobial activity of …
Article scientifique
Health seeking behaviour among suspected cases of cholera in Cameroonian health districts in Lake Chad basin
BACKGROUND: Cholera outbreaks are recurrent in Cameroon and despite the efforts put together during epidemics, they are always associated with …
Article scientifique
Immunization of cervidized transgenic mice with multimeric deer prion protein induces self-antibodies that antagonize chronic wasting disease infectivity in vitro
Abstract Chronic wasting disease (CWD) is the most contagious prion disease. It is expanding rapidly in North America, was found …
Article scientifique
Lactase persistence in Tunisia as a result of admixture with other Mediterranean populations
The ability to digest lactose after weaning, namely, lactase persistence (LP), is encoded by polymorphisms in the MCM6 gene and …
Article scientifique
Methyl pyruvate protects a normal lung fibroblast cell line from irinotecan-induced cell death: Potential use as adjunctive to chemotherapy
The Warburg Effect, characterized by increased rate of glycolysis even under normoxic conditions, is one of the hallmarks of cancer. …
Article scientifique
Evaluating the Causal Relation of ApoA-IV with Disease-Related Traits - A Bidirectional Two-sample Mendelian Randomization Study
Apolipoprotein A-IV (apoA-IV) has been observed to be associated with lipids, kidney function, adiposity- and diabetes-related parameters. To assess the …
Article scientifique
Photosensitive disorders in HIV
Photosensitive disorders are common, affecting up to 5% of HIV-positive patients. HIV itself induces photosensitivity but photoaggravated drug reactions, porphyria …