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Publications
4271 publication(s) trouvée(s)
Article scientifique
Methyl pyruvate protects a normal lung fibroblast cell line from irinotecan-induced cell death: Potential use as adjunctive to chemotherapy
The Warburg Effect, characterized by increased rate of glycolysis even under normoxic conditions, is one of the hallmarks of cancer. …
Article scientifique
Evaluating the Causal Relation of ApoA-IV with Disease-Related Traits - A Bidirectional Two-sample Mendelian Randomization Study
Apolipoprotein A-IV (apoA-IV) has been observed to be associated with lipids, kidney function, adiposity- and diabetes-related parameters. To assess the …
Article scientifique
Photosensitive disorders in HIV
Photosensitive disorders are common, affecting up to 5% of HIV-positive patients. HIV itself induces photosensitivity but photoaggravated drug reactions, porphyria …
Article scientifique
Low plasma vitamin A concentration is associated with tuberculosis in Moroccan population: a preliminary case control study
BACKGROUND: Vitamin A plays numerous roles in immune system. Its deficiency alters both the innate and adaptive immunity. Previous results …
Article scientifique
MALDI-TOF MS identification of Anopheles gambiae Giles blood meal crushed on Whatman filter papers
BACKGROUND: Identification of the source of mosquito blood meals is an important component for disease control and surveillance. Recently, matrix-assisted …
Article scientifique
Expression optimization of a cell membrane-penetrating human papillomavirus type 16 therapeutic vaccine candidate in Nicotiana benthamiana
High-risk human papillomaviruses (hr-HPVs) cause cervical cancer, the fourth most common cancer in women worldwide. A HPV-16 candidate therapeutic vaccine, …
Article scientifique
Gene Expression in Class 2 Integrons Is SOS-Independent and Involves Two Pc Promoters
Integrons are powerful bacterial genetic elements that permit the expression and dissemination of antibiotic-resistance gene cassettes. They contain a promoter …
Article scientifique
Endoglin inhibition leads to intussusceptive angiogenesis via activation of factors related to COUP-TFII signaling pathway
Angiogenesis is a highly coordinated, extremely complex process orchestrated by multiple signaling molecules and blood flow conditions. While sprouting mode …
Article scientifique
Identifying highly informative genetic markers for quantification of ancestry proportions in crossbred sheep populations: implications for choosing optimum levels of admixture
Understanding the relationship between genetic admixture and performances is crucial for the success of crossbreeding programs. Use of small sets …
Article scientifique
Breast cancer in Angola, molecular subtypes: a first glance
PURPOSE: The aim of this study was to investigate the breast cancer (BC) molecular subtypes according to its surrogate immunohistochemistry …
Article scientifique
Bone mineral density and risk of type 2 diabetes and coronary heart disease: A Mendelian randomization study
Background: Observational studies have demonstrated that increased bone mineral density is associated with a higher risk of type 2 diabetes …
Article scientifique
The neglected burden of snakebites in Cameroon: a review of the epidemiology, management and public health challenges
OBJECTIVES: Snakebite is an underestimated medical and surgical emergency in developing countries responsible for a high disease burden. Optimal management …
Article scientifique
A case report: primary amoebic meningoencephalitis in a young Zambian adult
BACKGROUND: Primary amoebic meningoencephalitis (PAM) is a fulminant disease of the brain caused by Naegleria fowleri. Although the disease is …
Article scientifique
Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos
Hypertension prevalence varies between ethnic groups, possibly due to differences in genetic, environmental, and cultural determinants. Hispanic/Latino Americans are a …
Article scientifique
Small molecule-based lineage switch of human adipose-derived stem cells into neural stem cells and functional GABAergic neurons
Cellular reprogramming using small molecules (SMs) without genetic modification provides a promising strategy for generating target cells for cell-based therapy. …
Article scientifique
Programmed cell death in Acanthamoeba castellanii Neff induced by several molecules present in olive leaf extracts
Therapy against Acanthamoeba infections such as Granulomatous Amoebic Encephalitis (GAE) and Acanthamoeba Keratitis (AK), remains as an issue to be …
Article scientifique
An intra-population analysis of the indris’ song dissimilarity in the light of genetic distance
The increasing interest in the evolution of human language has led several fields of research to focus on primate vocal …
Article scientifique
The Activity of the Neutral Sphingomyelinase Is Important in T Cell Recruitment and Directional Migration
Breakdown of sphingomyelin as catalysed by the activity of sphingomyelinases profoundly affects biophysical properties of cellular membranes which is particularly …
Article scientifique
High Spatial and Temporal Variations of Microbial Community along the Southern Catfish Gastrointestinal Tract: Insights into Dynamic Food Digestion
The fish intestinal microbiota is affected by dietary shifts or diet-related seasonal fluctuations making it highly variable and dynamic. It …
Article scientifique
Altitudinal gradients, biogeographic history and microhabitat adaptation affect fine-scale spatial genetic structure in African and Neotropical populations of an ancient tropical tree species
The analysis of fine-scale spatial genetic structure (FSGS) within populations can provide insights into eco-evolutionary processes. Restricted dispersal and locally …