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4155 publication(s) trouvée(s)
Article scientifique
An intra-population analysis of the indris’ song dissimilarity in the light of genetic distance
The increasing interest in the evolution of human language has led several fields of research to focus on primate vocal …
Article scientifique
The Activity of the Neutral Sphingomyelinase Is Important in T Cell Recruitment and Directional Migration
Breakdown of sphingomyelin as catalysed by the activity of sphingomyelinases profoundly affects biophysical properties of cellular membranes which is particularly …
Article scientifique
High Spatial and Temporal Variations of Microbial Community along the Southern Catfish Gastrointestinal Tract: Insights into Dynamic Food Digestion
The fish intestinal microbiota is affected by dietary shifts or diet-related seasonal fluctuations making it highly variable and dynamic. It …
Article scientifique
Altitudinal gradients, biogeographic history and microhabitat adaptation affect fine-scale spatial genetic structure in African and Neotropical populations of an ancient tropical tree species
The analysis of fine-scale spatial genetic structure (FSGS) within populations can provide insights into eco-evolutionary processes. Restricted dispersal and locally …
Article scientifique
Visual adaptation in Lake Victoria cichlid fishes: depth-related variation of color and scotopic opsins in species from sand/mud bottoms
BACKGROUND: For Lake Victoria cichlid species inhabiting rocky substrates with differing light regimes, it has been proposed that adaptation of …
Article scientifique
Classes 1 and 2 integrons in faecal Escherichia coli strains isolated from mother-child pairs in Nigeria
BACKGROUND: Antimicrobial resistance among enteric bacteria in Africa is increasingly mediated by integrons on horizontally acquired genetic elements. There have …
Article scientifique
The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells
Nature has provided us with a wide spectrum of disease healing phytochemicals like Artonin E, obtained from the root bark …
Article scientifique
Characterization and RNAi-mediated knockdown of Chitin Synthase A in the potato tuber moth, Phthorimaea operculella
Chitin is a major component of insect exoskeleton, tracheal system and gut where it is synthesized by chitin synthase (CHS) …
Article scientifique
Integrated Analysis of Copy Number Variations and Gene Expression Profiling in Hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the top three cancer killers worldwide. To identify CNV-driven differentially expressed genes (DEGs) in …
Article scientifique
From Farms to Markets: Gram-Negative Bacteria Resistant to Third-Generation Cephalosporins in Fruits and Vegetables in a Region of North Africa
The role of food in human exposure to antimicrobial-resistant bacteria is a growing food safety issue. The contribution of fruits …
Article scientifique
ssAAVs containing cassettes encoding SaCas9 and guides targeting hepatitis B virus inactivate replication of the virus in cultured cells
Management of infection with hepatitis B virus (HBV) remains a global health problem. Persistence of stable covalently closed circular DNA …
Article scientifique
Molecular determination of antimicrobial resistance in Escherichia coli isolated from raw meat in Addis Ababa and Bishoftu, Ethiopia
BACKGROUND: Consumption of meat contaminated by E. coli causes a serious illness and even death to affected individuals. Recently the …
Article scientifique
CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression
Impairment of intrinsic plasticity is involved in a range of neurological disorders such as epilepsy. However, how intrinsic excitability is …
Article scientifique
Therapeutic Potential of Selectively Targeting the α2C-Adrenoceptor in Cognition, Depression, and Schizophrenia—New Developments and Future Perspective
α2A- and α2C-adrenoceptors (AR) are the primary α2-AR subtypes involved in central nervous system (CNS) function. These receptors are implicated …
Article scientifique
Antibiotics resistance in El Tor Vibrio cholerae 01 isolated during cholera outbreaks in Mozambique from 2012 to 2015
RATIONALE: Mozambique has recorded cyclically epidemic outbreaks of cholera. Antibiotic therapy is recommended in specific situations for management and control …
Article scientifique
Plasmid-mediated mcr-1 colistin resistance in Escherichia coli and Klebsiella spp. clinical isolates from the Western Cape region of South Africa
Colistin is a last resort antibiotic for the treatment of carbapenem-resistant Gram negative infections. Until recently, mechanisms of colistin resistance …
Article scientifique
Reconstructing Asian faunal introductions to eastern Africa from multi-proxy biomolecular and archaeological datasets
Human-mediated biological exchange has had global social and ecological impacts. In sub-Saharan Africa, several domestic and commensal animals were introduced …
Article scientifique
Unraveling the gut microbiome of the long-lived naked mole-rat
The naked mole-rat (Heterocephalus glaber) is a subterranean mouse-sized African mammal that shows astonishingly few age-related degenerative changes and seems …
Article scientifique
Droplet digital polymerase chain reaction (ddPCR) assays integrated with an internal control for quantification of bovine, porcine, chicken and turkey species in food and feed
Food adulteration and feed contamination are significant issues in the food/feed industry, especially for meat products. Reliable techniques are needed …
Article scientifique
Peroxisome Proliferator-Activated Receptor Gamma in Obesity and Colorectal Cancer: the Role of Epigenetics
Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor that is deregulated in obesity. PPARγ exerts diverse antineoplastic effects. Attempting …