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Publications
4155 publication(s) trouvée(s)
Article scientifique
Are There Differences in Androgen Receptor Expression in Invasive Breast Cancer in African (Tanzanian) Population in Comparison With the Caucasian (Italian) Population?
PURPOSE: Androgen receptor (AR) has been shown to have prognostic implication on breast cancer (BC). Data on the biological features …
Article scientifique
Surfen and oxalyl surfen decrease tau hyperphosphorylation and mitigate neuron deficits in vivo in a zebrafish model of tauopathy
Abstract Background Tauopathies comprise a family of neurodegenerative disorders including Alzheimer’s disease for which there is an urgent and unmet …
Article scientifique
Evaluation of the selective toxic effect of the charge switchable diethyldithiocarbamate-loaded nanoparticles between hepatic normal and cancerous cells
Abstract Liver cancer is mainly originated by cancer stem cells (CSCs). Due to difference in pH between normal and tumor …
Article scientifique
Global and gene-specific DNA methylation in adult type 2 diabetic individuals: a protocol for a systematic review
BACKGROUND: DNA methylation (global and gene-specific) has been reported as an epigenetic mechanism that could be involved in the pathogenesis …
Article scientifique
Fatty Acids Rich Extract From Clerodendrum volubile Suppresses Cell Migration; Abates Oxidative Stress; and Regulates Cell Cycle Progression in Glioblastoma Multiforme (U87 MG) Cells
Glioblastoma multiform (GBM) is a malignant primary type of brain cancer with high proliferation and metastasis rates due to involvement …
Article scientifique
Multi-target mode of action of a Clerodane-type diterpenoid from Polyalthia longifolia targeting African trypanosomes
Abstract Natural products have made remarkable contributions to drug discovery and therapy. In this work we exploited various biochemical approaches …
Article scientifique
Evaluating the performance of tools used to call minority variants from whole genome short-read data
Background: High-throughput whole genome sequencing facilitates investigation of minority sub-populations from virus positive samples. Minority variants are useful in understanding …
Article scientifique
Inhibition of lipopolysaccharide (LPS)-induced neuroinflammatory response by polysaccharide fractions of Khaya grandifoliola (C.D.C.) stem bark, Cryptolepis sanguinolenta (Lindl.) Schltr and Cymbopogon citratus Stapf leaves in raw 264.7 macrophages and U87 glioblastoma cells
BACKGROUND: Khaya grandifoliola (C.D.C.) stem bark, Cymbopogon citratus (Stapf) and Cryptolepis sanguinolenta (Lindl.) Schltr leaves are used in Cameroonian traditional …
Article scientifique
Antimicrobial evaluation of red, phytoalexin-rich sorghum food biocolorant
Sorghum (Sorghum bicolor) extract is traditionally used as red biocolorant in West Africa to colour foods, among which wagashi, a …
Article scientifique
Aeromonas caviae mimicking Vibrio cholerae infectious enteropathy in a cholera-endemic region with possible public health consequences: two case reports
BACKGROUND: Aeromonas species have been documented to yield false positive results in microbiological tests for Vibrio cholerae. They share many …
Article scientifique
Potential human pathogenic bacteria in five hot springs in Eritrea revealed by next generation sequencing
Human pathogens can survive and grow in hot springs. For water quality assessment, Escherichia coli or Enterococci are the main …
Article scientifique
Cross-talk between primary osteocytes and bone marrow macrophages for osteoclastogenesis upon collagen treatment
Homeostasis of osteoclast formation from bone marrow macrophages (BMM) is regulated by paracrine signals of the neighbourhood bone cells particularly …
Article scientifique
Androctonus genus species in arid regions: Ecological niche models, geographical distributions, and envenomation risk
AIM: The objective of this study was to establish environmental factors related to scorpion species occurrence and their current potential …
Article scientifique
Traditional uses, phytochemistry and biological activities of Cotula cinerea Del: A review
Cotula cinerea Del. belongs to the family Asteraceae. It is widely used in the traditional medicinal system for the treatment …
Article scientifique
BRD7 expression and c-Myc activation forms a double-negative feedback loop that controls the cell proliferation and tumor growth of nasopharyngeal carcinoma by targeting oncogenic miR-141
BACKGROUND: miR-141 is up-regulated and plays crucial roles in nasopharyngeal carcinoma (NPC). However, the molecular mechanism underlying the dysregulation of …
Article scientifique
Eigen decomposition expedites longitudinal genome-wide association studies for milk production traits in Chinese Holstein
BACKGROUND: Pseudo-phenotypes, such as 305-day yields, estimated breeding values or deregressed proofs, are usually used as response variables for genome-wide …
Article scientifique
Transcriptomic and Ectoine Analysis of Halotolerant Nocardiopsis gilva YIM 90087T Under Salt Stress
The genus Nocardiopsis is a unique actinobacterial group that widely distributed in hypersaline environments. In this study, we investigated the …
Article scientifique
The management of diabetic ketoacidosis at a rural regional hospital in KwaZulu-Natal
BACKGROUND: Diabetic ketoacidosis (DKA) is a biochemical triad of hyperglycaemia, ketoacidosis and ketonaemia and one of the potentially life-threatening acute …
Article scientifique
Diversity and Antibiotic Susceptibility of Acinetobacter Strains From Milk Powder Produced in Germany
Forty seven Acinetobacter spp. isolates from milk powder obtained from a powdered milk producer in Germany were investigated for their …
Article scientifique
Selection and Clonal Propagation of High Artemisinin Genotypes of Artemisia annua
Artemisinin, produced in the glandular trichomes of Artemisia annua L. is a vital antimalarial drug effective against Plasmodium falciparum resistant …