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Publications
4155 publication(s) trouvée(s)
Article scientifique
A novel oral camptothecin analog, gimatecan, exhibits superior antitumor efficacy than irinotecan toward esophageal squamous cell carcinoma in vitro and in vivo
Abstract Esophageal squamous cell carcinoma (ESCC) is a frequently diagnosed and deadly malignancy with few standard therapeutic options. Camptothecins are …
Article scientifique
Antimicrobial and antioxidant activities of triterpenoid and phenolic derivatives from two Cameroonian Melastomataceae plants: Dissotis senegambiensis and Amphiblemma monticola
BACKGROUND: Antimicrobial resistance is a serious threat against humankind and the search for new therapeutics is needed. This study aims …
Article scientifique
Evaluation of anaesthetic protocols for laboratory adult zebrafish (Danio rerio)
In the last decades, the use of zebrafish (Danio rerio) in biomedical research has increased. Anaesthesia is daily used in …
Article scientifique
The Presence or Absence of Intestinal Microbiota Affects Lipid Deposition and Related Genes Expression in Zebrafish (Danio rerio)
Understanding how intestinal microbiota alters energy homeostasis and lipid metabolism is a critical process in energy balance and health. However, …
Article scientifique
Mitochondrial DNA is unsuitable to test for isolation by distance
Tests for isolation by distance (IBD) are the most commonly used method of assessing spatial genetic structure. Many studies have …
Article scientifique
Variation in faecal microbiota in a group of horses managed at pasture over a 12-month period
Colic (abdominal pain) is a common cause of mortality in horses. Change in management of horses is associated with increased …
Article scientifique
Matrix stiffness-upregulated LOXL2 promotes fibronectin production, MMP9 and CXCL12 expression and BMDCs recruitment to assist pre-metastatic niche formation
BACKGROUND: Higher matrix stiffness affects biological behavior of tumor cells, regulates tumor-associated gene/miRNA expression and stemness characteristic, and contributes to …
Article scientifique
Treemmer: a tool to reduce large phylogenetic datasets with minimal loss of diversity
BACKGROUND: Large sequence datasets are difficult to visualize and handle. Additionally, they often do not represent a random subset of …
Article scientifique
The contribution of culturomics to the repertoire of isolated human bacterial and archaeal species
After a decade of research and metagenomic analyses, our knowledge of the human microbiota appears to have reached a plateau …
Article scientifique
PROTOCOLS FOR PREPARATION OF BLOOD SMEARS, REPORTING OF MALARIA PARASITES, PROCESSING OF BLOOD SAMPLES USING MALARIA RDT (HRP-2), BLOOD GROUPING AND DESIGN OF QUESTIONNAIRE v1
LABORATORY PROTOCOLS FOR PREPARATION OF BLOOD SMEARS, REPORTING OF MALARIA PARASITES, PROCESSING OF BLOOD SAMPLES USING MALARIA RDT (HRP-2), BLOOD …
Article scientifique
KLK10 exon 3 unmethylated PCR product concentration: a new potential early diagnostic marker in ovarian cancer? - A pilot study
BACKGROUND: KLK10 exon 3 hypermethylation correlated to tumor-specific lack of KLK10 expression in cancer cell lines and primary tumors. In …
Article scientifique
Internal transcribed spacer for identification of yeast species isolated from cancer patients at the Isotope and Radiation Center, Khartoum, Sudan: A cross-sectional, case-control study
Background: Cancer patients have a high risk of fungal infections, especially by Candida species. Non- C. albicans Candida infections and …
Article scientifique
Evolution of computational models in BioModels Database and the Physiome Model Repository
BACKGROUND: A useful model is one that is being (re)used. The development of a successful model does not finish with …
Article scientifique
Enhancement of 5-HT2A receptor function and blockade of Kv1.5 by MK801 and ketamine: implications for PCP derivative-induced disease models
MK801 and ketamine, which are phencyclidine (PCP) derivative N-methyl-d-aspartate receptor (NMDAr) blockers, reportedly enhance the function of 5-hydroxytryptamine (HT)-2A receptors …
Article scientifique
Fusing metabolomics data sets with heterogeneous measurement errors
Combining different metabolomics platforms can contribute significantly to the discovery of complementary processes expressed under different conditions. However, analysing the …
Article scientifique
Characterization of Native Honey Bee Subspecies in Republic of Benin Using Morphometric and Genetic Tools
Abstract Morphometric characteristics combined with genetic markers are powerful tools used for determining honey bee subspecies. Bees samples collected from …
Article scientifique
Isobolographic analysis of co-administration of two plant-derived antiplasmodial drug candidates, cryptolepine and xylopic acid, in Plasmodium berghei
Increasing resistance to current anti-malarial therapies requires a renewed effort in searching for alternative therapies to combat this challenge, and …
Article scientifique
Interleukin-18 and its gene single nucleotide polymorphisms (SNPs) influence chronic hepatitis C progression
INTRODUCTION: Interleukin-18 (IL-18) is a pro-inflammatory cytokine that is induced by hepatitis C virus (HCV) infection. Inter-individual variations of IL-18 …
Article scientifique
Organizing and running bioinformatics hackathons within Africa: The H3ABioNet cloud computing experience
The need for portable and reproducible genomics analysis pipelines is growing globally as well as in Africa, especially with the …
Article scientifique
Unusual morphological adaptations and processes associated with viviparity in an epizoic dermapteran
Matrotrophic viviparity is a reproductive pattern in which offspring develop inside a female's body which provides gas exchange and nutrients …