Sciences de la santé

Article scientifique

Selective transmission of some HIV-1 subtype C variants might depend on Envelope stimulating dendritic cells to secrete IL-10

Envelope (Env) phenotype(s) that provide transmitted founders (TF) with a selective advantage during HIV-1 transmission would be the ideal target …

2020 Open Access

Article scientifique

Staffing in public health facilities after the Ebola outbreak in rural Sierra Leone: How much has changed?

Background: The 2014-2015 Ebola outbreak in Sierra Leone led the Ministry of Health and Sanitation to set minimum standards of …

2020 Open Access

Article scientifique

The prevalence and risk factors associated with Leptospira in donkeys in Ngaka Modiri Molema District, North West Province, South Africa

BACKGROUND AND AIM: Leptospirosis is one of the major emerging global economic and health problems affecting donkeys, thereby reducing their …

2020 Open Access

Article scientifique

Prevalence of Newcastle disease virus in feces of free-range turkeys in Enugu, Nigeria

BACKGROUND AND AIM: Newcastle disease (ND) virus of free-range turkeys may be linked to outbreaks of ND in backyard chickens …

2020 Open Access

Article scientifique

A simple and efficient purification method of native immunoreactive antigen for diagnosis of camel hydatidosis

Background: Cystic echinococcosis (CE), a zoonotic disease that affects animal and human health, is of increasing economic importance due to …

2020 Open Access

Article scientifique

Age, period and cohort analysis of age-specific maternal mortality trend in Ethiopia: A secondary analysis

BACKGROUND: Maternal mortality (MM) was persistently high for several decades in Ethiopia though it has declined in recent years. The …

2020 Open Access

Article scientifique

Antitumor activity of methoxylated flavonoids separated from Achillea fragrantissima extract in Ehrlich’s ascites carcinoma model in mice

Introduction: Achillea fragrantissima extract has been used in folk medicine as an anticancer. The present study describes the antitumor activities …

2020 Open Access

Article scientifique

Interpreting Mamelodi Community-Oriented Primary Care data on tuberculosis loss to follow-up through the lens of intersectionality

BACKGROUND: Tuberculosis (TB) is a persistent major public health challenge in South Africa. This article examines the social determinants and …

2020 Open Access

Article scientifique

Prevalence of hearing loss and tinnitus in a group of adults with Human Immunodeficiency Virus

BACKGROUND: The Human Immunodeficiency Virus (HIV) has become a global pandemic. With the improvement of antiretroviral (ARV) treatment regimens, life-expectancy …

2020 Open Access

Article scientifique

Dietary diversity among school age children in Merawi town, Amhara region, Ethiopia, 2018: a community based cross-sectional study

BACKGROUND: Malnutrition with its constituents of protein energy malnutrition and micro-nutrient deficiencies continues to be a major health burden in …

2020 Open Access

Article scientifique

Doctors experiences on the quality of care for pesticide poisoning patients in hospitals in Kampala, Uganda: a qualitative exploration using donabedian’s model

BACKGROUND: Pesticides are responsible for a significant percentage of deaths globally with majority occurring in sub-Saharan Africa. Deaths due to …

2020 Open Access

Article scientifique

Full genomic characterization of a porcine rotavirus strain detected in an asymptomatic piglet in Accra, Ghana

BACKGROUND: The introduction of rotavirus A vaccination across the developing world has not proved to be as efficacious as first …

2020 Open Access

Article scientifique

The effects of oral administration of Cola nitida on the pharmacokinetic profile of metoclopramide in rabbits

BACKGROUND: Cola nitida is commonly chewed in many West African cultures to ease hunger pangs and sometimes for their stimulant …

2020 Open Access

Article scientifique

Cost effectiveness of a novel device for improving resuscitation of apneic newborns

BACKGROUND: Intrapartum-related hypoxic events are a major cause of morbidity and mortality in low resource countries. Neonates who receive proper …

2020 Open Access

Article scientifique

Task shifting for point-of-care early infant diagnosis: a comparison of the quality of testing between nurses and laboratory personnel in Zimbabwe

Abstract Background To decentralize point-of-care early infant diagnosis (POC EID), task shifting to cadres such as nurses is important. However, …

2020 Open Access

Article scientifique

Late clinical failure associated with cytochrome b codon 268 mutation during treatment of falciparum malaria with atovaquone–proguanil in traveller returning from Congo

BACKGROUND: The drug combination atovaquone-proguanil, is recommended for treatment of uncomplicated falciparum malaria in France. Despite high efficacy, atovaquone-proguanil treatment …

2020 Open Access

Article scientifique

A study to better understand under-utilization of laboratory tests for antenatal care in Senegal

OBJECTIVE: To better understand factors contributing to underutilization of laboratory services for health care delivery in sub-Saharan Africa, we conducted …

2020 Open Access

Article scientifique

Factors associated with typical enteropathogenicEscherichia coliinfection among children <5 years old with moderate-to-severe diarrhoea in rural western Kenya, 2008–2012

Typical enteropathogenic Escherichia coli (tEPEC) infection is a major cause of diarrhoea and contributor to mortality in children <5 years …

2020 Open Access

Article scientifique

Feeding and developmental outcomes of infants in a South African community

BACKGROUND: Prevalent environmental risk factors place infants in lower-middle-income countries (LMICs) at an increased risk for feeding and developmental difficulties. …

2020 Open Access

Article scientifique

Correlating maternal iodine status with neonatal thyroid function in two hospital populations in Ghana: a multicenter cross-sectional pilot study

BACKGROUND: Congenital hypothyroidism is a common, yet easily treatable cause of poor growth and intellectual disability. Newborn screening programs play …

2020 Open Access