94 publication(s) trouvée(s)
Article scientifique
Community-level antibiotic access and use (ABACUS) in low- and middle-income countries: Finding targets for social interventions to improve appropriate antimicrobial use – an observational multi-centre study
In many low- and middle-income countries (LMICs), a poor link between antibiotic policies and practices exists. Numerous contextual factors may …
Article scientifique
A geo-coded inventory of anophelines in the Afrotropical Region south of the Sahara: 1898-2016
Background : Understanding the distribution of anopheline vectors of malaria is an important prelude to the design of national malaria …
Article scientifique
Amodiaquine resistance in Plasmodium berghei is associated with PbCRT His95Pro mutation, loss of chloroquine, artemisinin and primaquine sensitivity, and high transcript levels of key transporters
Background: The human malaria parasite Plasmodium falciparum has evolved complex drug evasion mechanisms to all available antimalarials. To date, the …
Article scientifique
Liquid chromatography–tandem mass spectrometry for the simultaneous quantitation of ceftriaxone, metronidazole and hydroxymetronidazole in plasma from seriously ill, severely malnourished children
We have developed and validated a novel, sensitive, selective and reproducible reversed-phase high-performance liquid chromatography method coupled with electrospray ionization …
Article scientifique
Antimalarial drugs and the prevalence of mental and neurological manifestations: A systematic review and meta-analysis
Background: Antimalarial drugs affect the central nervous system, but it is difficult to differentiate the effect of these drugs from …
Article scientifique
Geographic-genetic analysis of Plasmodium falciparum parasite populations from surveys of primary school children in Western Kenya
Background. Malaria control, and finally malaria elimination, requires the identification and targeting of residual foci or hotspots of transmission. However, …
Article scientifique
PARV4 prevalence, phylogeny, immunology and coinfection with HIV, HBV and HCV in a multicentre African cohort
Background: The seroprevalence of human parvovirus-4 (PARV4) varies considerably by region. In sub-Saharan Africa, seroprevalence is high in the general …
Article scientifique
Variation in the effectiveness of insecticide treated nets against malaria and outdoor biting by vectors in Kilifi, Kenya
Background: Insecticide treated nets (ITNs) protect humans against bites from the Anopheles mosquito vectors that transmit malaria, thereby reducing malaria …
Article scientifique
Quantification and determinants of the amount of respiratory syncytial virus (RSV) shed using real time PCR data from a longitudinal household study
Background : A better understanding of respiratory syncytial virus (RSV) epidemiology requires realistic estimates of RSV shedding patterns, quantities shed, …
Article scientifique
Mapping the distribution of Anopheles funestus across Benin highlights a sharp contrast of susceptibility to insecticides and infection rate to Plasmodium between southern and northern populations
Background. Malaria remains an important public health issue in Benin, with Anopheles gambiae s.l. and Anopheles funestus s.s being the …
Article scientifique
Antimalarial drugs and the prevalence of mental and neurological manifestations: A systematic review and meta-analysis
Background: Antimalarial drugs affect the central nervous system, but it is difficult to differentiate the effect of these drugs from …
Article scientifique
Micro-epidemiological structuring of Plasmodium falciparum parasite populations in regions with varying transmission intensities in Africa.
Background: The first models of malaria transmission assumed a completely mixed and homogeneous population of parasites. Recent models include spatial …
Article scientifique
First report of the East African kdr mutation in an Anopheles gambiae mosquito in Côte d’Ivoire
Background . The intensive use of insecticides in public health and agriculture has led to the development of insecticide resistances …
Article scientifique
Crude childhood vaccination coverage in West Africa: Trends and predictors of completeness
Background : Africa has the lowest childhood vaccination coverage worldwide. If the full benefits of childhood vaccination programmes are to …
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