90 publication(s) trouvée(s)
Article scientifique
Strengthening ethical community engagement in contemporary Malawi
Although community engagement is increasingly promoted in global health research to improve ethical research practice, there is sometimes a disconnect …
Article scientifique
Modifying Intestinal Integrity and MicroBiome in Severe Malnutrition with Legume-Based Feeds (MIMBLE 2.0): protocol for a phase II refined feed and intervention trial
Background: Changes in intestinal mucosal integrity and gut microbial balance occur in severe acute malnutrition (SAM), resulting in treatment failure …
Article scientifique
Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial
Background: Postpartum haemorrhage (PPH) is a leading cause of maternal death. The WOMAN trial showed that tranexamic acid (TXA) reduces …
Article scientifique
H3Africa: crucial importance of knowledge on human demographic history in strategies for data exploitation – an analysis of the Luhya in Webuye, Kenya population from the 1000 Genomes Project
Paucity of data from African populations has restricted understanding of the heritable human genome variation. Although under-represented in human genetic …
Article scientifique
Surveillance of respiratory viruses in the outpatient setting in rural coastal Kenya: baseline epidemiological observations
Background: Endemic and seasonally recurring respiratory viruses are a major cause of disease and death globally. The burden is particularly …
Article scientifique
Geographical distribution of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) and genetic diversity of invading population of Ae. albopictus in the Republic of the Congo
Background: The arbovirus vector, Aedes albopictus, originating from Asia, has recently invaded African countries, including the Republic of the Congo, …
Article scientifique
Ophthalmic signs in Ugandan adults with HIV-associated cryptococcal meningitis: A nested analysis of the ASTRO-CM cohort
Cryptococcal meningitis is a leading cause of morbidity and mortality among HIV-infected persons, accounting for 15% of AIDS-related deaths. Visual …
Article scientifique
Surveillance and Epidemiology of Drug Resistant Infections Consortium (SEDRIC): Supporting the transition from strategy to action
In recognition of the central importance of surveillance and epidemiology in the control of antimicrobial resistance and the need to …
Article scientifique
Smartphones for community health in rural Cambodia: A feasibility study
Background: Village Malaria Workers (VMWs) are lay people trained to provide a valuable role in frontline testing and treatment of …
Article scientifique
Non-financial incentives and professional health workers’ intentions to stay in public district hospitals in Rwanda: A cross-sectional study
Background: Evidence shows that human resources represent a pillar that supports the healthcare system. As a result, retaining the health …
Article scientifique
Neonatal nursing policy and practice in Kenya: Key stakeholders and their views on task-shifting as an intervention to improve care quality.
Background: Improving the quality of facility based neonatal care is central to tackling the burden of neonatal mortality in Low …
Article scientifique
ANIMA: Association network integration for multiscale analysis
Contextual functional interpretation of -omics data derived from clinical samples is a classical and difficult problem in computational systems biology. …
Article scientifique
Evaluating the performance of tools used to call minority variants from whole genome short-read data
Background: High-throughput whole genome sequencing facilitates investigation of minority sub-populations from virus positive samples. Minority variants are useful in understanding …
Article scientifique
Detection and quantification of Anopheles gambiae sensu lato mosquito larvae in experimental aquatic habitats using environmental DNA (eDNA).
Background: Growing insecticide resistance and changes in biting and resting behavior of malaria vectors threaten efficacy of insecticide treated nets …
Article scientifique
First report of the presence of L1014S Knockdown-resistance mutation in Anopheles gambiae s.s and Anopheles coluzzii from Togo, West Africa
Background: To optimize the success of insecticide-based malaria control intervention, knowledge of the distribution of Anopheles gambiae species and insecticide …
Article scientifique
Using theories of change to design monitoring and evaluation of community engagement in research: experiences from a research institute in Malawi
Background: Evaluation of community and public engagement in research is important to deepen understanding of how engagement works and to …
Article scientifique
A hidden burden of neonatal illness? A cross-sectional study of all admissions aged less than one month across twelve Kenyan County hospitals
Background: Small and sick newborns need high quality specialised care within health facilities to address persistently high neonatal mortality in …
Article scientifique
Water source most suitable for rearing a sensitive malaria vector, Anopheles funestus in the laboratory
Background: The insecticide susceptibility status ofAnopheles funestus,one of the main malaria vectors in the Afrotropical regions, remains under-studied due to …
Article scientifique
A hidden burden of neonatal illness? A cross-sectional study of all admissions aged less than one month across twelve Kenyan County hospitals
Background: Small and sick newborns need high quality specialised care within health facilities to address persistently high neonatal mortality in …
Article scientifique
Comparative genomics identifies male accessory gland proteins in five Glossina species
Accessory gland proteins (ACPs) are important reproductive proteins produced by the male accessory glands (MAGs) of most insect species. These …