73 publication(s) trouvée(s)
Article scientifique
Variation in the observed effect of Xpert MTB/RIF testing for tuberculosis on mortality: A systematic review and analysis of trial design considerations
Background: Most studies evaluating the effect of Xpert MTB/RIF testing for tuberculosis (TB) concluded that it did not reduce overall …
Article scientifique
Asthma control and management among schoolchildren in urban Uganda: results from a cross-sectional study
Background : Children from low- and middle-income countries have poor asthma control, mainly because of poor management. The extent of …
Article scientifique
Management of intracranial tuberculous mass lesions: how long should we treat for?
Tuberculous intracranial mass lesions are common in settings with high tuberculosis (TB) incidence and HIV prevalence. The diagnosis of such …
Article scientifique
The Ministry of Health and Sanitation, Sierra Leone – Public Health England (MOHS-PHE) Ebola Biobank
During the Ebola outbreak in 2014-2015 in Sierra Leone, residual clinical specimens and accompanying data were collected from routine diagnostic …
Article scientifique
Bayesian evaluation of the performance of three diagnostic tests for Plasmodium falciparum infection in a low-transmission setting in Kilifi County, Kenya
Background: Central to the successful elimination of Plasmodium falciparum malaria, are tests with superior capability of diagnosing low-density parasitaemias. Empirical …
Article scientifique
Gut mucosal colonisation with extended-spectrum beta-lactamase producing Enterobacteriaceae in sub-Saharan Africa: a systematic review and meta-analysis
Background : Extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) threaten human health; and, in areas of sub-Saharan Africa (sSA) where carbapenems are …
Article scientifique
Ophthalmic features of HIV associated cryptococcal meningitis in Malawian Adults: an observational study
Background: Cryptococcal meningitis (CM) is the commonest neurological complication in patients with advanced HIV. Visual disturbance is a frequent presenting …
Article scientifique
Cost-effectiveness of reflex laboratory-based cryptococcal antigen screening for the prevention and treatment of cryptococcal meningitis in Botswana
Background: Cryptococcal antigen (CrAg) screening for antiretroviral therapy (ART)-naïve adults with advanced HIV/AIDS can reduce the incidence of cryptococcal meningitis …
Article scientifique
The Ministry of Health and Sanitation – Public Health England (MOHS-PHE) Ebola Biobank
During the Ebola outbreak in 2014-2015 in Sierra Leone, residual clinical specimens and accompanying data were collected from routine diagnostic …
Article scientifique
Traditional eye medicine use in microbial keratitis in Uganda: a mixed methods study
Background : Traditional eye medicine (TEM) is frequently used to treat microbial keratitis (MK) in many parts of Africa. Few …
Article scientifique
Competing risk survival analysis of time to in-hospital death or discharge in a large urban neonatal unit in Kenya
Background: Clinical outcomes data are a crucial component of efforts to improve health systems globally. Strengthening of these health systems …
Article scientifique
Prevalence of impaired renal function among rural and urban populations: findings of a cross-sectional study in Malawi
Background : Sub-Saharan Africa faces region-specific risk factors for chronic kidney disease (CKD), such as nephrotoxic herbal medicines, antiretroviral therapy …
Article scientifique
A Malawi guideline for research study participant remuneration
Background: Research participant remuneration has been variable and inconsistent world-wide for many years owing to uncertainty regarding best practice and …
Article scientifique
Geographical distribution of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) and genetic diversity of invading population of Ae. albopictus in the Republic of the Congo
Background: The arbovirus vector, Aedes albopictus, originating from Asia, has recently invaded African countries, including the Republic of the Congo, …
Article scientifique
A Malawi guideline for research study participant remuneration
Background: Research participant remuneration has been variable and inconsistent world-wide for many years owing to uncertainty regarding best practice and …
Article scientifique
Seasonal upsurge of pneumococcal meningitis in the Central African Republic
A high incidence of bacterial meningitis was observed in the Central African Republic (CAR) from December 2015 to May 2017 …
Article scientifique
Health risk behavior among perinatally HIV exposed uninfected adolescents: A systematic review
Background : Perinatally HIV exposed uninfected (PHEU) adolescents are an increasing sub-population, especially in high HIV epidemic settings. HIV exposure …
Article scientifique
Ophthalmic signs in Ugandan adults with HIV-associated cryptococcal meningitis: A nested analysis of the ASTRO-CM cohort
Cryptococcal meningitis is a leading cause of morbidity and mortality among HIV-infected persons, accounting for 15% of AIDS-related deaths. Visual …
Article scientifique
Importance of human demographic history knowledge in genetic studies involving multi-ethnic cohorts
Paucity of data from African populations due to under-representation in human genetic studies has impeded detailed understanding of the heritable …
Article scientifique
Implementing a quality management system using good clinical laboratory practice guidelines at KEMRI-CMR to support medical research
Background: Good Clinical Laboratory Practice (GCLP) is a standard that helps ensure the quality and reliability of research data through …
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