309 publication(s) trouvée(s)
Article scientifique
Synthesis of N-substituted acetamide derivatives of azinane-bearing 1,3,4-oxadiazole nucleus and screening for antibacterial activity
Purpose: To synthesize some acetamide derivatives bearing azinane and 1,3,4-oxadiazole heterocyclic cores and to evaluate their antibacterial potentials.Methods: Ethyl piperidin-4-carboxylate …
Article scientifique
Phytochemical screening, cytotoxicity and acute toxicity of Annona vepretorum Mart (Annonaceae) leaf extracts
Purpose: To investigate the phytochemistry, cytotoxicity and acute toxicity of leaf extracts from Annona vepretorum.Methods: The crude extracts were obtained …
Article scientifique
Physicochemical properties and lubricant potentials of Blighia sapida Sapindaceaeae seed oil in solid dosage formulations
Purpose: To investigate and compare the physicochemical properties and lubricant potentials of Blighia sapida seed oil (BSSO) with those of …
Article scientifique
Pharmacological activities and pharmacokinetic study of hyperoside: A short review
Hyperoside (quercetin-3-O-D-galactoside) is a flavonol glycoside which has been isolated from different plants. It has different pharmacological actions such as …
Article scientifique
Detection of drug-induced dyslipidaemia in HIV-positive patients treated with protease inhibitors in a South African district – A retrospective study
Purpose: To determine whether protease inhibitors (PIs) cause hypercholesterolaemia and hypertriglyceridaemia, and to assess the influence of sex and age …
Article scientifique
Effect of topical application of two Polygala tenuifolia species decoction on guinea pig skin
Purpose: To investigate the effect of the topical decoction of Polygala tenuifolia Willd. and Polygala sibirica L. on a guinea …
Article scientifique
Effect of acetone extract of Rumex japonicas Houtt on hydrogen peroxide-induced apoptosis in rat myocardial cells
Purpose: To investigate the protective effect of the acetone extract of Rumex japonicas Houtt. (AER) on rat myocardial cells.Methods: R. …
Article scientifique
Effect of physical and flexibility exercise on certain hormones and fasting blood sugar of some young Nigerian adults
Purpose: To investigate the effect of six (6) weeks physical and flexibility exercise on fasting blood sugar and some hormones …
Article scientifique
Chemical composition of Dipsacus asper Wallich ex Candolle (Dipsacaceae) essential oil and its activity against mosquito larvae of Aedes aegypti and Culex pipiens pallens
Purpose: To evaluate the larvicidal activity of the essential oil of Dipsacus asper Wallich ex Candolle (Dipsacaceae) roots against the …
Article scientifique
Effect of Carica papaya (Linn) aqueous leaf extract on pharmacokinetic profile of ciprofloxacin in rabbits
Purpose: To investigate the fate of ciprofloxacin, after concomitant administration with the aqueous leaf extract of Carica papaya, which herbal …
Article scientifique
Tangeretin sensitises human lung cancer cells to TRAILinduced apoptosis via ROS-JNK/ERK-CHOP pathwaymediated up-regulation of death receptor 5
Purpose: To investigate the efficacy of tangeretin, a bioactive flavonoid, as an enhancer of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced …
Article scientifique
Diagnostic utility of leptin and insulin-like growth factor binding protein-2 in hepatocellular carcinoma of diabetic and non-diabetic Egyptian patients
Purpose: To elucidate the possible diagnostic utility of adipokines and insulin growth factor binding proteins in hepatocellular carcinoma (HCC) diabetic …
Article scientifique
Assessment of oral safety profile of aqueous extract blend of three medicinal spices in Wistar rats
Purpose: To evaluate the possible toxicity of a blend of three spices, namely, garlic (Allium sativum), ginger (Zingiber officinale) and …
Article scientifique
Anti-tumor activity of polysaccharides extracted from Senecio scandens Buch, -Ham root on hepatocellular carcinoma
Purpose: To optimize the extraction conditions of polysaccharides from the root of Senecio scandens Buch,-Ham. (PRS) and evaluate its anti-tumor …
Article scientifique
Volatile compounds and biological activities of aerial parts of Pituranthos scoparius (Coss and Dur) Schinz (Apiaceae) from Hoggar, southern Algeria
Purpose: To determine the chemical composition as well as in vitro antimicrobial and antioxidant activities of the Pituranthos scoparius essential …
Article scientifique
Physical characterization and kinetic modelling of matrix tablets of ketorolac tromethamol formulated with polymers and waxes
Purpose: To design controlled release ketorolac tromethamol (KT) matrix tablets for increased drug bioavailability.Methods: Waxes (Compritol® ATO 888, Precirol® ATO …
Article scientifique
Therapeutic effect of He-Wei-Tong-Xie decoction on acute pancreatitis complicated with gastrointestinal dysfunction
Purpose: To study the therapeutic effect of He-Wei-Tong-Xie (HWXT) decoction on acute pancreatitis (AP) complicated with gastrointestinal dysfunction.Methods: AP patients …
Article scientifique
Evaluation of neuroprotective properties of two synthetic prenylated xanthone analogues against paraquat and 6- hydroxydopamine toxicity in human neuroblastoma SHSY5Y cells
Purpose: To investigate whether two synthetic prenylated xanthone analogues - 1,3,6,8-tetrahydroxy- 9H-xanthen-9-one (SX1) and 1,3,6-trihydroxy-2-(3-methylbut-2-enyl)-9H-xanthen-9-one (SX2) - are potential candidates …
Article scientifique
Herbal antihyperlipidemic formulation of cocoa tea: Preparation and in vivo comparison with atorvastatin
Purpose: To prepare and characterize a formulation containing an ethanol extract of Camellia ptilophylla leaves (cocoa tea), with a focus …
Article scientifique
In vitro inhibitory effect of methanol leaf extract of Stachytarpheta jamaicensis (Verbenaceae) on nonpregnant rat uterus
Purpose: To investigate the effect of the methanol extract of the plant, Stachytarpheta jamaicensis (Verbenaceae) (SJ) on uterine smooth muscles …