309 publication(s) trouvée(s)
Article scientifique
Asiatic acid attenuates malignancy of human metastatic ovarian cancer cells via inhibition of epithelial-tomesenchymal transition
Purpose: To investigate the anticancer effects of asiatic acid on human metastatic ovarian cancer cells.Methods: Human metastatic ovarian cancer cell …
Article scientifique
Pharmacodynamic and cytotoxicity effects of Syzygium cordatum {S Ncik, 48 (UZ)} fruit-pulp extract in gastrointestinal tract infections
Purpose: To evaluate the pharmacodynamic effect and cytotoxicity of S. cordatum pulp extract in the treatment of gastrointestinal tract infections.Methods: …
Article scientifique
Benefits afforded by combined temozolomide, radiation and stem cell strategy for glioma therapy
Purpose: To compare the efficacy of temozolomide, radiation and stem cell therapy in glioma management.Methods: A total of 112 patients …
Article scientifique
Inhibitory effect of rhubarb on intestinal α-glucosidase activity in type 1 diabetic rats
Purpose: To investigate the inhibitory effect of rhubarb on α-glucosidase activity in the small intestine of rats with type 1 …
Article scientifique
Effect of particle size and diluent type on critical parameters for disintegration of tablets containing croscarmellose sodium as a disintegrant
Purpose: The aim of the present work was to determine the effect of particle size and type of diluents on …
Article scientifique
Effect of different drying techniques on the volatile compounds, morphological characteristics and thermal stability of Stevia rebaudiana Bertoni leaf
Purpose: To examine the volatile compounds, thermal stability and morphological characteristics of stevia (Stevia rebaudiana Bertoni) leaves after sun, oven …
Article scientifique
Anti-hyperuricemic effect of Plantago depressa Willd extract in rats
Purpose: To investigate the effects of Plantago depressa Willd. extract (PDWE) on hyperuricemia in rats.Methods: The effect of PDWE was …
Article scientifique
Pain symptoms in patients with severe cerebral palsy: Prevalence among patients with higher degree of locomotor impairment
Purpose: To evaluate the presence of pain in patients diagnosed with severe cerebral palsy (CP) according to the degree of …
Article scientifique
Simultaneous determination of ten compounds in two main medicinal plant parts of Tibetan herb, Pterocephalus hookeri (CB Clarke) Höeck, by ultra-high performance liquid chromatography-photodiode array
Purpose: To develop an ultra-high performance liquid chromatography (UPLC) - photodiode array (PDA) method to compare the chemical composition of …
Article scientifique
Enhanced antitumor activity of cabazitaxel targeting CD44+ receptor in breast cancer cell line via surface functionalized lipid nanocarriers
Purpose: To investigate the properties of surface-functionalized, hyaluronic acid-coated, cabazitaxelloaded solid lipid nanoparticles (HA-CZ-SLNs) for the treatment of breast cancer.Methods: …
Article scientifique
Missed medical appointment among hypertensive and diabetic outpatients in a tertiary healthcare facility in Ibadan, Nigeria
Purpose: To explore the reasons for missed medical appointment, patients’ awareness on its consequences; and to find strategies to reduce …
Article scientifique
Okra (Abelmoschus esculentus Linn) inhibits lipopolysaccharide-induced inflammatory mediators in BV2 microglial cells
Purpose: To investigate the inhibitory effects of okra (Abelmoschus esculentus Linn.) extract on the production of reactive oxygen species (ROS) …
Article scientifique
Guizhi-jia-houpu-xingzi decoction attenuates ovalbumin-induced allergic asthma via regulation of Toll-like receptor signal pathway
Purpose: To study the effect of Guizhi-jia-houpu-xingzi (GHX) on ovalbumin-induced allergic asthma in rats.Methods: An animal model of allergic asthma …
Article scientifique
Preparation of resistant sweet potato starch by steam explosion technology using response surface methodology
Purpose: To obtain the optimal conditions and analyze the structure, gelatinization, and digestion characteristics of resistant sweet potato starch prepared …
Article scientifique
Neuroprotective effects of thymoquinone against cerebellar histopathological changes in propylthiouracilinduced hypothyroidism in adult rats
Purpose: To evaluate the effects of thymoquinone (TQ) on histological and immunohistochemical changes in the cerebellar cortex induced by propylthiouracil …
Article scientifique
Effect of Alisma plantago-aquatica Linn extract on chronic prostatitis in rats
Purpose: To study the effect of Alisma plantago-aquatica Linn. extract (APLE) on chronic prostatitis in rats.Methods: Experimental chronic non-bacterial prostatitis …
Article scientifique
Eosinophilia triggers changes in IL-5, eotaxin and IL-17, and acts as a prognostic biomarker for atopic dermatitis
Purpose: To investigate the implication of eosinophilia in atopic dermatitis (AD).Methods: A total of 139 AD patients from The First …
Article scientifique
Green tea polyphenol induces significant cell death in human lung cancer cells
Purpose: To investigate the dose–response relationship of green tea polyphenol in an animal model of lung cancer.Methods: The effects of …
Article scientifique
Hypercalcaemia in patients with breast cancer: Patterns and treatment outcomes among in-patients in a Malaysian tertiary healthcare facility
Purpose: To assess the patterns of use of bisphosphonate therapies for hypercalcaemia in breast cancer patients, and their outcomes.Methods: A …
Article scientifique
Neuroprotective effects of α-lipoic acid against hypoxic– ischemic brain injury in neonatal rats
Purpose: To explore the neuroprotective efficacy of α-lipoic acid (ALA) against hypoxic-ischemic encephalopathy (HIE) in neonatal rats.Methods: Forty-eight rats (P7-pups) …