101 publication(s) trouvée(s)
Article scientifique
Disclosure of human immunodeficiency virus status to children in South Africa: A comprehensive analysis
BACKGROUND: The extent of disclosure of HIV status to children and adolescents and the context facilitating their disclosure process have …
Article scientifique
Rapid emergence of resistance to antiretroviral treatment after undisclosed prior exposure: A case report
INTRODUCTION: Patients who disengaged from care may present as therapy naïve for antiretroviral treatment (ART) initiation at a different site, …
Article scientifique
Switching at Low HIV-1 RNA into Fixed Dose Combinations: TDF/FTC/RPV is non-inferior to TDF/FTC/EFV in first-line suppressed patients living with HIV
Background: In low- and middle-income countries (LMICs), a substantial unmet need for affordable single-tablet regimen (STR) options remains. Rilpivirine (RPV, …
Article scientifique
Factors influencing the confidence and knowledge of nurses prescribing antiretroviral treatment in a rural and urban district in the Western Cape province
BACKGROUND: Since the introduction of nurse-initiated and managed antiretroviral treatment (NIMART) in South Africa in 2010, initiation of antiretroviral therapy …
Article scientifique
Outcomes of Stevens–Johnson syndrome and toxic epidermal necrolysis in HIV-infected patients when using systemic steroids and/or intravenous immunoglobulins in Pietermaritzburg, South Africa
BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe life-threatening mucocutaneous reactions. There is an ongoing controversy regarding …
Article scientifique
Baseline CD4 and mortality trends in the South African human immunodeficiency virus programme: Analysis of routine data
Background: Despite widespread availability of antiretroviral therapy (ART) in South Africa, there remains a considerable burden of human immunodeficiency virus …
Article scientifique
A descriptive analysis of the role of a WhatsApp clinical discussion group as a forum for continuing medical education in the management of complicated HIV and TB clinical cases in a group of doctors in the Eastern Cape, South Africa
BACKGROUND: As South Africa's (SA) HIV programme increases in size, HIV/TB cases occur that are often beyond the clinical scope …
Article scientifique
Peripartum HIV infection in very low birth weight infants fed ‘raw’ mother’s own milk
BACKGROUND: HIV-exposed very low birth weight (VLBW) infants (≤ 1500 g) are considered at high risk of peripartum mother-to-child HIV …
Article scientifique
Vaginal practices among women at risk for HIV acquisition in Soweto, South Africa
Background: Vaginal practices (VP) may adversely affect normal vaginal flora and mucosal integrity, and increase acquisition risk of HIV and …
Article scientifique
A cross-sectional study of the factors associated with male circumcision status among college youth in Ndola, Zambia, 2016
Background: New cases of HIV are increasing among young adults in Zambia; yet voluntary medical male circumcision (VMMC) coverage as …
Article scientifique
HIV testing at birth: Are we getting it right?
BACKGROUND: Birth polymerase chain reaction (PCR) testing improves early detection of HIV and allows for early treatment initiation. National guidelines …
Article scientifique
Cognitive and behavioural determinants of multiple sexual partnerships and condom use in South Africa: Results of a national survey
BACKGROUND: Human immunodeficiency virus (HIV) risky behaviours including multiple sexual partnership (MSP) and non-condom use (nCU) are known to be …
Article scientifique
Self-reported risky sexual practices among adolescents and young adults in Botswana
BACKGROUND: Adolescents and young adults account for more than one-third of incident Human Immunodeficiency Virus (HIV) infections globally. Understanding sexual …
Article scientifique
The role of rilpivirine in Southern Africa
Rilpivirine, a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), is included as an option in first-line antiretroviral therapy (ART) for antiretroviral-naïve …
Article scientifique
Tonsil histopathology in HIV-infected versus HIV-uninfected adults
BACKGROUND: The relationship between HIV and tonsil malignancy has not been fully investigated and established. Both of these diseases prominently …
Article scientifique
Sexual behaviours, awareness and perceptions towards voluntary medical male circumcision among students in Dr Kenneth Kaunda District, South Africa
Background: Voluntary Medical Male Circumcision (VMMC) is regarded as the most cost-effective intervention in reducing female-to-male transmission of HIV in …
Article scientifique
Comparison of non-invasive methods of assessing liver fibrosis in combination ART-experienced Zimbabweans
Background: The prevalence of morbidity and mortality associated with liver disease among HIV-infected individuals on combination antiretroviral therapy (ART) is …
Article scientifique
Correlation of hair and plasma efavirenz concentrations in HIV-positive South Africans
Background: Antiretroviral concentrations in hair provide a longer window of drug detection and are useful for measuring longer-term drug exposure. …
Article scientifique
Knowledge about male circumcision and perception of risk for HIV among youth in Harare, Zimbabwe
BACKGROUND: Male circumcision will require high uptake among previously non-circumcising countries to realise the impact of circumcising in preventing HIV. …
Article scientifique
HIV viraemia during pregnancy in women receiving preconception antiretroviral therapy in KwaDukuza, KwaZulu-Natal
BACKGROUND: Preconception antiretroviral therapy (PCART) followed by sustained viral suppression is effective in preventing mother-to-child transmission of HIV. The rates …