6057 publication(s) trouvée(s)
Article scientifique
Neonatal, infant and under-five mortalities in Nigeria: An examination of trends and drivers (2003-2013)
Neonatal (NMR), infant (IMR) and under-five (U5M) mortality rates remain high in Nigeria. Evidence-based knowledge of trends and drivers of …
Article scientifique
Factors associated with stunting in healthy children aged 5 years and less living in Bangui (RCA)
Stunting remains a major public health concern worldwide. Although its global prevalence is slowly decreasing, the actual number of affected …
Article scientifique
Recentralization within decentralization: County hospital autonomy under devolution in Kenya
BACKGROUND: In 2013, Kenya transitioned into a devolved system of government with a central government and 47 semi-autonomous county governments. …
Article scientifique
Sanitation facilities, hygienic conditions, and prevalence of acute diarrhea among under-five children in slums of Addis Ababa, Ethiopia: Baseline survey of a longitudinal study
BACKGROUND: In developing countries, children under the age of five years who live in slums are highly vulnerable to diarrhea. …
Article scientifique
Child contact management in high tuberculosis burden countries: A mixed-methods systematic review
Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide. Considering the World Health Organization recommendation to implement child …
Article scientifique
2D Ti3C2Tx (MXene)-reinforced polyvinyl alcohol (PVA) nanofibers with enhanced mechanical and electrical properties
Novel 2D Ti3C2Tx (MXene)-reinforced polyvinyl alcohol (PVA) nanofibers have been successfully fabricated by an electrospinning technique. The high aspect ratio, …
Article scientifique
Transfusion-transmissible viral infections among blood donors at the North Gondar district blood bank, northwest Ethiopia: A three year retrospective study
BACKGROUND: Transfusion-transmissible viral infections, such as hepatitis C virus (HCV), hepatitis B virus (HBV), and human immunodeficiency virus (HIV), remain …
Article scientifique
Generation of an artificial human B cell line test system using Transpo-mAbTM technology to evaluate the therapeutic efficacy of novel antigen-specific fusion proteins
The antigen-specific targeting of autoreactive B cells via their unique B cell receptors (BCRs) is a novel and promising alternative …
Article scientifique
The effects of ingestion of hormonal host factors on the longevity and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae)
Exogenous vertebrate-derived factors circulating in the blood have the capacity to modulate the biology of haematophagous insects. These include insulin, …
Article scientifique
Pituitary adenylate cyclase-activating polypeptide (PACAP) in zebrafish models of nephrotic syndrome
Pituitary adenylate cyclase-activating polypeptide (PACAP) is an inhibitor of megakaryopoiesis and platelet function. Recently, PACAP deficiency was observed in children …
Article scientifique
APOL1 risk alleles among individuals with CKD in Northern Tanzania: A pilot study
INTRODUCTION: In sub-Saharan Africa, approximately 100 million people have CKD, yet genetic risk factors are not well-understood. Despite the potential …
Article scientifique
Gender differences in cerebral metabolism for color processing in mice: A PET/MRI Study
INTRODUCTION: Color processing is a central component of mammalian vision. Gender-related differences of color processing revealed by non-invasive functional transcranial …
Article scientifique
A retrospective case-cohort study comparing treatment outcomes in abacavir versus stavudine containing first line antiretroviral treatment regimens in children <3yrs old, at a paediatric programme based in Soweto, South Africa
INTRODUCTION: The current World Health Organization guideline for first line antiretroviral therapy (ART) in HIV-infected children recommends the use of …
Article scientifique
Young Sprague Dawley rats infected by Plasmodium berghei: A relevant experimental model to study cerebral malaria
Cerebral malaria (CM) is the most severe manifestation of human malaria yet is still poorly understood. Mouse models have been …
Article scientifique
Impact of thyroid function abnormalities on reproductive hormones during menstrual cycle in premenopausal HIV infected females at NAUTH, Nnewi, Nigeria
BACKGROUND: This was a prospective study designed to evaluate the impact of thyroid function abnormalities on reproductive hormones during menstrual …
Article scientifique
Performance characteristics of finger-stick dried blood spots (DBS) on the determination of human immunodeficiency virus (HIV) treatment failure in a pediatric population in Mozambique
Quantitative plasma viral load (VL) at 1000 copies /mL was recommended as the threshold to confirm antiretroviral therapy (ART) failure …
Article scientifique
The cost effectiveness of a quality improvement program to reduce maternal and fetal mortality in a regional referral hospital in Accra, Ghana
OBJECTIVE: To evaluate the cost-effectiveness of a quality improvement intervention aimed at reducing maternal and fetal mortality in Accra, Ghana. …
Article scientifique
Predisposition to insulin resistance and obesity due to staple consumption of rice: Amylose content versus germination status
Type 2 diabetes is a metabolic disorder with established, well-defined precursors. Obesity and insulin resistance are amongst most important factors …
Article scientifique
Assessing development assistance for child survival between 2000 and 2014: A multi-sectoral perspective
BACKGROUND: The majority of Countdown countries did not reach the fourth Millennium Development Goal (MDG 4) on reducing child mortality, …
Article scientifique
Early infant diagnosis of HIV-1 infection in Luanda, Angola, using a new DNA PCR assay and dried blood spots
BACKGROUND: Early diagnosis and treatment reduces HIV-1-related mortality, morbidity and size of viral reservoirs in infants infected perinatally. Commercial molecular …