6057 publication(s) trouvée(s)
Article scientifique
The multi-country PROMOTE HIV antiretroviral treatment observational cohort in Sub-Saharan Africa: Objectives, design, and baseline findings
BACKGROUND: The PROMOTE study aims to measure long-term antiretroviral treatment (ART) safety and adherence; compare HIV disease progression; assess subsequent …
Article scientifique
The adjuvant AlhydroGel elicits higher antibody titres than AddaVax when combined with HIV-1 subtype C gp140 from CAP256
With the HIV-1 epidemic in southern Africa still rising, a prophylactic vaccine against the region's most prolific subtype (subtype C) …
Article scientifique
Molecular characterisation of the NDM-1-encoding plasmid p2189-NDM in an Escherichia coli ST410 clinical isolate from Ghana
Global dissemination of New Delhi metallo-β-lactamase (NDM)-producing bacteria has become a major health threat. However, there are few reports regarding …
Article scientifique
HIV-1 subtype diversity, transmission networks and transmitted drug resistance amongst acute and early infected MSM populations from Coastal Kenya
BACKGROUND: HIV-1 molecular epidemiology amongst men who have sex with men (MSM) in sub-Saharan Africa remains not well characterized. We …
Article scientifique
Mycobacterium africanum (Lineage 6) shows slower sputum smear conversion on tuberculosis treatment than Mycobacterium tuberculosis (Lineage 4) in Bamako, Mali
OBJECTIVE: Ancestral M. tuberculosis complex lineages such as M. africanum are underrepresented among retreatment patients and those with drug resistance. …
Article scientifique
Pseudomonas coronafaciens sp. nov., a new phytobacterial species diverse from Pseudomonas syringae
We propose Pseudomonas coronafaciens sp. nov. as a new species in genus Pseudomonas, which is diverse from P. syringae. We …
Article scientifique
Colorectal cancer survival rates in Ghana: A retrospective hospital-based study
BACKGROUND: Colorectal cancer (CRC) is one of the commonest cancers associated with diverse prognosis times in different parts of the …
Article scientifique
Predictors of malaria Rapid Diagnostic Tests’ utilisation among healthcare workers in Zamfara State
INTRODUCTION: Early diagnosis and prompt and effective treatment is one of the pillars of malaria control. Malaria case management guidelines …
Article scientifique
'I should not feed such a weak woman'. Intimate partner violence among women living with podoconiosis: A qualitative study in northern Ethiopia
BACKGROUND: Intimate Partner Violence (IPV) is a serious, preventable public health problem that affects millions of people worldwide. Research indicates …
Article scientifique
Mapping the epidemiological distribution and incidence of major zoonotic diseases in South Tigray, North Wollo and Ab’ala (Afar), Ethiopia
Zoonotic diseases continue to affect the health and livelihood of resource limited communities. In Ethiopia, despite the presence of a …
Article scientifique
Hospitalization and post-discharge care in South Africa: A critical event in the continuum of care
OBJECTIVES: The purpose of this prospective cohort study is to characterize the event of acute hospitalization for people living with …
Article scientifique
Discontinuing cotrimoxazole preventive therapy in HIV-infected adults who are stable on antiretroviral treatment in Uganda (COSTOP): A randomised placebo controlled trial
BACKGROUND: Cotrimoxazole (CTX) preventive therapy (CPT) reduces opportunistic infections and malaria in HIV-infected patients. In Africa, policies on sustained CPT …
Article scientifique
Trends in misoprostol use and abortion complications: A cross-sectional study from nine referral hospitals in Nigeria
OBJECTIVE: The study aimed to assess the use of misoprostol and complications associated with abortions in referral hospitals in Nigeria, …
Article scientifique
Clusters of high abundance of plants detected from local indicators of spatial association (LISA) in a semi-deciduous tropical forest
Plants are rarely randomly distributed across communities, and patchiness is a common spatial pattern in most tropical forests. Clusters of …
Article scientifique
Leucine rich repeat kinase 2 (LRRK2) GLY2019SER mutation is absent in a second cohort of Nigerian Africans with Parkinson disease
To date the LRRK2 p.G2019S mutation remains the most common genetic cause of Parkinson disease (PD) worldwide. It accounts for …
Article scientifique
Toll-like receptor chaperone HSP90B1 and the immune response to Mycobacteria
RATIONALE: HSP90B1, also known as gp96, is a chaperone for multiple Toll-like receptors (TLRs) and is necessary for TLR-mediated inflammatory …
Article scientifique
Loop-mediated isothermal amplification (LAMP) and Polymerase Chain Reaction (PCR) as quality assurance tools for Rapid Diagnostic Test (RDT) malaria diagnosis in Northern Namibia
Malaria cases sometimes go undetected using RDTs due to their inaccurate use, poor storage conditions and failure to detect low …
Article scientifique
Uterine rupture among mothers admitted for obstetrics care and associated factors in referral hospitals of Amhara regional state, institution-based cross-sectional study, Northern Ethiopia, 2013-2017
BACKGROUND: Maternal morbidity and mortality have been one of the most challenging health problems that concern the globe over the …
Article scientifique
Blood neutrophil counts in HIV-infected patients with cryptococcal meningitis: Association with mortality
BACKGROUND: The mortality from cryptococcal meningitis remains high, despite the availability of antiretroviral therapy (ART) and amphotericin-based fungal regimens. The …
Article scientifique
Characteristics and early clinical outcomes of key populations attending comprehensive community-based HIV care: Experiences from Nasarawa State, Nigeria
BACKGROUND: Despite a call for differentiated care, there are limited data from sub-Saharan Africa on comprehensive community-based HIV care for …